Development Level

Tbio 82 | 11,651
Tdark 4 | 6,593
Tchem 3 | 1,388
Tclin 2 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal bone structure 3 | 187
decreased body length 2 | 101
decreased body weight 2 | 161
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal facial morphology 1 | 17
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal retina morphology 1 | 71
cleft palate 1 | 8
cyanosis 1 | 7
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
impaired glucose tolerance 1 | 75
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 59 | 11,493
ovarian cancer 41 | 8,520
psoriasis 39 | 6,694
glioblastoma 36 | 5,792
osteosarcoma 36 | 7,950
Breast cancer 35 | 3,578
atypical teratoid / rhabdoid tumor 34 | 5,112
ependymoma 33 | 4,679
medulloblastoma, large-cell 32 | 6,241
malignant mesothelioma 26 | 3,232
lung cancer 25 | 4,740
Kidney cancer 24 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
invasive ductal carcinoma 24 | 2,951
adult high grade glioma 22 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
Autosomal recessive predisposition 21 | 1,442
Cancer 21 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
Astrocytoma, Pilocytic 20 | 3,081
lung adenocarcinoma 20 | 2,716
group 3 medulloblastoma 18 | 4,104
oligodendroglioma 18 | 2,850
Myopathy 17 | 185
colon cancer 17 | 1,478
primitive neuroectodermal tumor 17 | 3,035
adrenocortical carcinoma 16 | 1,428
ductal carcinoma in situ 16 | 1,745
non-small cell lung cancer 16 | 2,890
Creatine phosphokinase serum increased 15 | 110
Elevated creatine kinase 15 | 110
Muscular dystrophy 15 | 75
acute quadriplegic myopathy 15 | 1,158
breast carcinoma 15 | 1,638
group 4 medulloblastoma 15 | 1,855
lung carcinoma 15 | 2,843
pituitary cancer 15 | 1,972
diabetes mellitus 14 | 1,728
Intellectual disability 13 | 1,016
astrocytic glioma 13 | 2,597
pancreatic cancer 13 | 2,398
cystic fibrosis 12 | 1,696
juvenile dermatomyositis 12 | 1,187
subependymal giant cell astrocytoma 12 | 2,287
Obesity 11 | 678
interstitial cystitis 11 | 2,312
Acquired scoliosis 10 | 281
Contracture 10 | 96
Contracture of joint 10 | 93
Curvature of spine 10 | 282
Flexion contracture 10 | 93
Flexion contractures of joints 10 | 93
Liver cancer 10 | 604
Muscle biopsy shows dystrophic changes 10 | 39
limb-girdle muscular dystrophy 10 | 37
medulloblastoma 10 | 720
pediatric high grade glioma 10 | 1,064
Cardiomyopathy 9 | 116
Duchenne muscular dystrophy 9 | 601
Dull intelligence 9 | 645
Heart disease 9 | 306
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Motor delay 9 | 147
No development of motor milestones 9 | 147
Poor school performance 9 | 645
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
Atopic dermatitis 8 | 952
Epilepsy 8 | 792
Hypoplastic mandible condyle 8 | 275
Liver Cirrhosis, Experimental 8 | 769
Lordosis 8 | 54
Mandibular hypoplasia 8 | 275
Micrognathism 8 | 275
Orbital separation excessive 8 | 244
Schizophrenia 8 | 1,160
dermatomyositis 8 | 966
nasopharyngeal carcinoma 8 | 1,058
primary pancreatic ductal adenocarcinoma 8 | 1,109
tuberculosis 8 | 2,010
ulcerative colitis 8 | 1,819
Cleft Palate 7 | 271
Muscle hypotonia 7 | 571
Neuropathy 7 | 261
Pick disease 7 | 1,894
Prostatic Neoplasms 7 | 495
Scapular weakness 7 | 23
Seizures 7 | 596
Uranostaphyloschisis 7 | 167
Winged scapula 7 | 23
active ulcerative colitis 7 | 764
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Bipolar Disorder 6 | 666
Cardiomyopathy, Dilated 6 | 83
Small head 6 | 374
Vascular disease 6 | 319
active Crohn's disease 6 | 922
astrocytoma 6 | 1,146
fibroadenoma 6 | 559

Tissue

Male tissues 90 | 17,142
Skin and soft tissues 90 | 17,230
Digestive Tract 89 | 17,369
Endocrine System 89 | 18,159
Female tissues 89 | 17,400
Urinary Tract 87 | 16,678
Liver and Pancreas 86 | 16,750
Nervous System 86 | 16,725
Respiratory system 86 | 16,393
Blood and immune system 85 | 16,909
Cardiovascular System 83 | 15,192

Target Family

Non-IDG 56 | 12,091
Transcription Factor 25 | 1,400
Enzyme 3 | 4,145
Epigenetic 3 | 242
Kinase 2 | 634
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

muscle organ development 91 | 91
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Striated muscle preferentially expressed protein kinase SPEG Tbio Kinase -2.50316 309.8 65
EP300-interacting inhibitor of differentiation 2 EID2 Tbio Non-IDG -1.36642 21.1 65
Integrin beta-1-binding protein 2 ITGB1BP2 Tbio Non-IDG -1.09897 15.9 165
Four and a half LIM domains protein 3 FHL3 Tbio Non-IDG -0.71819 5.67 103
Myocyte-specific enhancer factor 2D MEF2D Tbio Transcription Factor -1.96264 88.6 323
Proline-rich protein 14 PRR14 Tbio Non-IDG -0.76170 6.46 60
Tripartite motif-containing protein 72 TRIM72 Tbio Non-IDG -1.98480 94.6 146
Mitogen-activated protein kinase 12 MAPK12 Tchem Kinase -1.95173 88.4 378
Blood vessel epicardial substance BVES Tbio Non-IDG -1.50394 37.0 168