Development Level

Tbio 36 | 11,445
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

embryonic lethality prior to t... 2 | 278
increased circulating chloride... 2 | 41
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal heart morphology 1 | 162
abnormal response to new envir... 1 | 10
abnormal skin morphology 1 | 50
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
hyperactivity 1 | 148
increased blood uric acid leve... 1 | 5
increased circulating alkaline... 1 | 122
increased circulating iron lev... 1 | 30
increased granulocyte number 1 | 1
increased heart weight 1 | 62
increased startle reflex 1 | 112
long tibia 1 | 25

Disease

Carcinoma 24 | 11,493
psoriasis 22 | 6,694
Hypertrophic Cardiomyopathy 18 | 117
acute quadriplegic myopathy 18 | 1,158
Cardiomyopathy, Dilated 16 | 83
Dilated cardiomyopathy 16 | 56
Myopathy 16 | 185
Cardiomyopathy 15 | 116
Autosomal recessive predisposition 14 | 1,442
Distal arthrogryposis 14 | 42
Familial isolated dilated cardiomyopathy 13 | 41
LEFT VENTRICULAR NONCOMPACTION 10 13 | 40
LEFT VENTRICULAR NONCOMPACTION 8 13 | 40
Breast cancer 12 | 3,578
glioblastoma 12 | 5,792
lung cancer 12 | 4,740
atypical teratoid / rhabdoid tumor 11 | 5,112
ovarian cancer 11 | 8,520
Acquired scoliosis 10 | 281
Curvature of spine 10 | 282
Kidney cancer 10 | 2,613
medulloblastoma, large-cell 10 | 6,241
osteosarcoma 10 | 7,950
Byzanthine arch palate 9 | 194
Congestive heart failure 9 | 113
Duchenne muscular dystrophy 9 | 601
group 3 medulloblastoma 9 | 4,104
Arthrogryposis 8 | 54
Melanoma 8 | 711
Skin cancer 8 | 469
diabetes mellitus 8 | 1,728
lung adenocarcinoma 8 | 2,716
malignant mesothelioma 8 | 3,232
primitive neuroectodermal tumor 8 | 3,035
Astrocytoma, Pilocytic 7 | 3,081
Bell Palsy 7 | 58
Blepharoptosis 7 | 231
Cardiomyopathy, Hypertrophic, Familial 7 | 9
Facial Paresis 7 | 59
Facial muscle weakness of muscles innervated by CN VII 7 | 58
Generalized muscle weakness 7 | 57
Heart failure 7 | 162
Left ventricular noncompaction 7 | 26
Narrow face 7 | 54
Nemaline myopathy 7 | 17
Proximal muscle weakness 7 | 47
Proximal neurogenic muscle weakness 7 | 47
Thin face 7 | 54
ependymoma 7 | 4,679
pancreatic cancer 7 | 2,398
Amyotrophic lateral sclerosis 6 | 451
Becker muscular dystrophy 6 | 191
Bulbar palsy 6 | 19
Bulbar weakness 6 | 19
Clubfoot 6 | 39
Congenital clubfoot 6 | 109
Deglutition Disorders 6 | 132
Distal arthrogryposis syndrome 6 | 8
EMG: myopathic abnormalities 6 | 22
Feeding difficulties 6 | 127
Liver cancer 6 | 604
Neck muscle weakness 6 | 17
Respiratory insufficiency due to muscle weakness 6 | 37
adult high grade glioma 6 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
colon cancer 6 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
invasive ductal carcinoma 6 | 2,951
limb girdle muscular dystrophy 2A 6 | 213
Adducted thumb 5 | 22
Cardiac Arrhythmia 5 | 103
Cardiac conduction abnormalities 5 | 78
Conduction disorder of the heart 5 | 79
Creatine phosphokinase serum increased 5 | 110
EKG abnormalities 5 | 78
Electrocardiogram abnormal 5 | 81
Electrocardiogram change 5 | 78
Elevated creatine kinase 5 | 110
Failure to gain weight 5 | 365
Flexion contracture of proximal interphalangeal joint 5 | 75
Heart disease 5 | 306
Highly variable severity 5 | 157
Joint stiffness 5 | 84
Motor delay 5 | 147
Neonatal Hypotonia 5 | 64
No development of motor milestones 5 | 147
Overlapping fingers 5 | 10
Pediatric failure to thrive 5 | 365
Prenatal onset 5 | 139
Reduced fetal movement 5 | 51
Respiratory Insufficiency 5 | 132
Respiratory function loss 5 | 121
Toeing-in 5 | 24
Ulnar deviation of the fingers 5 | 21
Variable expressivity 5 | 157
Waddling gait 5 | 34
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
juvenile dermatomyositis 5 | 1,187
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890

Tissue

Endocrine System 38 | 18,159
Skin and soft tissues 38 | 17,230
Digestive Tract 37 | 17,369
Male tissues 37 | 17,142
Cardiovascular System 36 | 15,192
Urinary Tract 36 | 16,678
Blood and immune system 35 | 16,909
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Nervous System 33 | 16,725
Respiratory system 30 | 16,393

Target Family

Non-IDG 37 | 12,091
Kinase 1 | 634

GO Process

muscle filament sliding 38 | 38
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Tropomyosin alpha-4 chain TPM4 Tbio Non-IDG -1.57899 37.4 120
Myosin light chain 1/3, skeletal muscle isoform MYL1 Tbio Non-IDG -2.11698 129.3 109
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Titin TTN Tbio Kinase -3.24415 1743.0 123
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Myosin-8 MYH8 Tbio Non-IDG -1.71003 48.7 39
Myosin-3 MYH3 Tbio Non-IDG -1.74714 48.2 51
Myosin light chain 6B MYL6B Tdark Non-IDG -0.48723 2.69 127