Development Level

Tbio 7 | 11,445
Tchem 2 | 1,598
Tclin 2 | 613
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal heart morphology 1 | 162
abnormal spine curvature 1 | 9
decreased circulating serum al... 1 | 82
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
enlarged heart 1 | 210
hyperactivity 1 | 148
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased monocyte cell number 1 | 63

Disease

Carcinoma 9 | 11,493
ovarian cancer 8 | 8,520
psoriasis 8 | 6,694
colon cancer 5 | 1,478
ependymoma 5 | 4,679
medulloblastoma, large-cell 5 | 6,241
Astrocytoma, Pilocytic 4 | 3,081
Autosomal recessive predisposition 4 | 1,442
Muscle Weakness 4 | 170
atypical teratoid / rhabdoid tumor 4 | 5,112
cystic fibrosis 4 | 1,696
glioblastoma 4 | 5,792
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
Cancer 3 | 2,499
Cardiomyopathies 3 | 110
Cardiomyopathy 3 | 116
Creatine phosphokinase serum increased 3 | 110
Elevated creatine kinase 3 | 110
Muscle hypotonia 3 | 571
Myopathy 3 | 185
Neuropathy 3 | 261
adult high grade glioma 3 | 3,801
ductal carcinoma in situ 3 | 1,745
hereditary spastic paraplegia 3 | 318
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
pancreatic cancer 3 | 2,398
Acquired scoliosis 2 | 281
Adult onset 2 | 82
Atrophy of cerebellum 2 | 103
Babinski Reflex 2 | 100
Blepharoptosis 2 | 231
Breast cancer 2 | 3,578
Calf muscle pseudohypertrophy 2 | 5
Cerebellar Dysmetria 2 | 56
Cerebellar degeneration 2 | 103
Curvature of spine 2 | 282
Decreased tendon reflex 2 | 122
Difficulty walking up stairs 2 | 12
Dilated cardiomyopathy 2 | 56
Disease Models, Animal 2 | 155
Endometrial cancer 2 | 311
Infratentorial atrophy 2 | 103
Kidney cancer 2 | 2,613
Muscle biopsy shows dystrophic changes 2 | 39
Muscular dystrophy 2 | 75
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Neurodegenerative disease 2 | 414
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Peripheral Neuropathy 2 | 134
Pick disease 2 | 1,894
Progressive disorder 2 | 142
Respiratory Insufficiency 2 | 132
Respiratory function loss 2 | 121
Skeletal muscle atrophy 2 | 139
Slow progression 2 | 89
Waddling gait 2 | 34
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
muscle degeneration 2 | 139
oligodendroglioma 2 | 2,850
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Ataxia, Appendicular 1 | 25
Bronchiectasis 1 | 64
Dysdiadochokinesis 1 | 25
Dysmetric saccades 1 | 9
Early myoclonic encephalopathy 1 | 15
Gas gangrene 1 | 17
Increased intramyocellular lipid droplets 1 | 13
Leiomyosarcoma 1 | 24
Lower limb hyperreflexia 1 | 10
Muscle atrophy, proximal 1 | 11
Narrow face 1 | 54
Nystagmus, End-Position 1 | 12
Ophthalmoparesis 1 | 11
PARKINSON DISEASE, LATE-ONSET 1 | 20
Paraparesis, Spastic 1 | 16
Pilomatrixoma 1 | 12
SPASTIC ATAXIA 5, AUTOSOMAL RECESSIVE 1 | 1
SPINOCEREBELLAR ATAXIA 28 1 | 1
Sebaceous Gland Neoplasms 1 | 1
Slowed saccades 1 | 12
Spastic Ataxia 1 | 18
Thin face 1 | 54
Tonic - clonic seizures 1 | 44
spinocerebellar ataxia type 28 1 | 3

Tissue

Female tissues 12 | 17,400
Nervous System 12 | 16,725
Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 2 | 4,145
Ion Channel 2 | 344
Transcription Factor 1 | 1,400

GO Process

muscle fiber development 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pentatricopeptide repeat-containing protein 2, mitochondrial PTCD2 Tdark Non-IDG -0.06695 1.01 131
AFG3-like protein 2 AFG3L2 Tbio Enzyme -1.58716 39.9 164
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 WFIKKN2 Tbio Non-IDG -0.70376 4.95 94
Ubiquitin carboxyl-terminal hydrolase isozyme L1 UCHL1 Tchem Enzyme -3.16318 1414.2 1378
Beta-sarcoglycan SGCB Tbio Non-IDG -2.98252 853.7 151
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 WFIKKN1 Tbio Non-IDG -0.69215 6.16 30
Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 Tclin Ion Channel -1.59683 37.4 101
Lymphoid enhancer-binding factor 1 LEF1 Tchem Transcription Factor -2.60971 375.2 591
Acetylcholine receptor subunit beta CHRNB1 Tclin Ion Channel -1.26222 17.9 180
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform MYL2 Tbio Non-IDG -2.23022 155.8 222