Development Level

Tbio 76 | 11,445
Tclin 15 | 613
Tchem 8 | 1,598
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 4 | 99

IMPC Phenotype

preweaning lethality, complete... 4 | 979
increased hematocrit 3 | 46
abnormal behavior 2 | 298
abnormal behavioral response t... 2 | 66
abnormal embryo size 2 | 220
abnormal sleep behavior 2 | 70
decreased bone mineral content 2 | 151
decreased lean body mass 2 | 135
decreased startle reflex 2 | 75
edema 2 | 59
hyperactivity 2 | 148
increased leukocyte cell numbe... 2 | 47
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
abnormal bone structure 1 | 187
abnormal facial morphology 1 | 17
abnormal motor learning 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal placenta vasculature 1 | 2
abnormal vocalization 1 | 21
absent startle reflex 1 | 24
convulsive seizures 1 | 13
cyanosis 1 | 7
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased urine creatinine lev... 1 | 3
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased anxiety-related resp... 1 | 2
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased hemoglobin content 1 | 45
increased or absent threshold ... 1 | 101
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
respiratory system phenotype 1 | 2

Disease

Carcinoma 65 | 11,493
psoriasis 57 | 6,694
osteosarcoma 41 | 7,950
ovarian cancer 41 | 8,520
glioblastoma 36 | 5,792
atypical teratoid / rhabdoid tumor 35 | 5,112
Breast cancer 34 | 3,578
medulloblastoma, large-cell 30 | 6,241
lung cancer 27 | 4,740
Kidney cancer 25 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
invasive ductal carcinoma 25 | 2,951
Autosomal recessive predisposition 24 | 1,442
colon cancer 24 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
Myopathy 23 | 185
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
malignant mesothelioma 23 | 3,232
pancreatic cancer 23 | 2,398
acute quadriplegic myopathy 22 | 1,158
ependymoma 22 | 4,679
group 3 medulloblastoma 22 | 4,104
lung adenocarcinoma 22 | 2,716
adult high grade glioma 20 | 3,801
lung carcinoma 19 | 2,843
primitive neuroectodermal tumor 19 | 3,035
breast carcinoma 18 | 1,638
Astrocytoma, Pilocytic 16 | 3,081
Duchenne muscular dystrophy 16 | 601
ductal carcinoma in situ 16 | 1,745
Blepharoptosis 15 | 231
non-small cell lung cancer 15 | 2,890
subependymal giant cell astrocytoma 15 | 2,287
Cardiomyopathy 14 | 116
Skin cancer 14 | 469
cystic fibrosis 14 | 1,696
group 4 medulloblastoma 14 | 1,855
pituitary cancer 14 | 1,972
Epilepsy 13 | 792
Melanoma 13 | 711
astrocytic glioma 13 | 2,597
diabetes mellitus 13 | 1,728
oligodendroglioma 13 | 2,850
Bell Palsy 12 | 58
Cardiomyopathy, Dilated 12 | 83
Creatine phosphokinase serum increased 12 | 110
Deglutition Disorders 12 | 132
Elevated creatine kinase 12 | 110
Facial Paresis 12 | 59
Facial muscle weakness of muscles innervated by CN VII 12 | 58
Muscular dystrophy 12 | 75
adrenocortical carcinoma 12 | 1,428
Heart disease 11 | 306
Hypertrophic Cardiomyopathy 11 | 117
Proximal muscle weakness 11 | 47
Proximal neurogenic muscle weakness 11 | 47
juvenile dermatomyositis 11 | 1,187
primary pancreatic ductal adenocarcinoma 11 | 1,109
tuberculosis 11 | 2,010
ulcerative colitis 11 | 1,819
Atopic dermatitis 10 | 952
Byzanthine arch palate 10 | 194
Dilated cardiomyopathy 10 | 56
Feeding difficulties 10 | 127
Highly variable severity 10 | 157
Liver Cirrhosis, Experimental 10 | 769
Liver cancer 10 | 604
Neck muscle weakness 10 | 17
Pick disease 10 | 1,894
Prenatal onset 10 | 139
Variable expressivity 10 | 157
aldosterone-producing adenoma 10 | 665
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
EMG: myopathic abnormalities 9 | 22
Failure to gain weight 9 | 365
Infantile onset 9 | 238
Long face 9 | 71
Motor delay 9 | 147
Muscle hypotonia 9 | 571
Neonatal Hypotonia 9 | 64
No development of motor milestones 9 | 147
Pediatric failure to thrive 9 | 365
Respiratory Insufficiency 9 | 132
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
Amyotrophic lateral sclerosis 8 | 451
Becker muscular dystrophy 8 | 191
Cancer 8 | 2,499
Distal limb muscle weakness due to peripheral neuropathy 8 | 62
Distal muscle weakness 8 | 62
Generalized muscle weakness 8 | 57
Highly variable clinical phenotype 8 | 150
Highly variable phenotype and severity 8 | 150
Highly variable phenotype, even within families 8 | 150
LEFT VENTRICULAR NONCOMPACTION 10 8 | 40
Phenotypic variability 8 | 150
Respiratory function loss 8 | 121
Respiratory insufficiency due to muscle weakness 8 | 37
Seizures 8 | 596
pancreatic carcinoma 8 | 562
spina bifida 8 | 1,074

Tissue

Endocrine System 100 | 18,159
Skin and soft tissues 98 | 17,230
Digestive Tract 97 | 17,369
Male tissues 97 | 17,142
Blood and immune system 93 | 16,909
Female tissues 92 | 17,400
Urinary Tract 92 | 16,678
Cardiovascular System 91 | 15,192
Liver and Pancreas 91 | 16,750
Nervous System 90 | 16,725
Respiratory system 85 | 16,393

Target Family

Non-IDG 68 | 12,091
Ion Channel 17 | 344
Enzyme 5 | 4,145
GPCR 5 | 408
Kinase 3 | 634
Transporter 2 | 473
Transcription Factor 1 | 1,400

GO Process

muscle contraction 101 | 101
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin-13 MYH13 Tbio Non-IDG -1.26079 16.6 12
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
Myosin light chain 1/3, skeletal muscle isoform MYL1 Tbio Non-IDG -2.11698 129.3 109
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Tclin Ion Channel -2.48671 270.6 121
Leiomodin-3 LMOD3 Tbio Non-IDG -1.00928 10.3 27
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Myosin regulatory light chain 2, atrial isoform MYL7 Tbio Non-IDG -0.85198 5.20 169
Alpha-1-syntrophin SNTA1 Tbio Non-IDG -1.49227 31.4 254
Polyadenylate-binding protein 2 PABPN1 Tbio Non-IDG -2.48757 316.4 120