Development Level

Tbio 6 | 11,445

IMPC Phenotype

abnormal cornea morphology 1 | 31
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
cataract 1 | 92
corneal opacity 1 | 32
decreased lean body mass 1 | 135
fused cornea and lens 1 | 5
impaired pupillary reflex 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased total body fat amoun... 1 | 134
iris synechia 1 | 3
narrow eye opening 1 | 12
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979

Disease

Myopathy 4 | 185
Carcinoma 3 | 11,493
Cleft Palate 3 | 271
Orbital separation excessive 3 | 244
Skeletal muscle neoplasm 3 | 8
Acquired scoliosis 2 | 281
Bilateral fifth finger clinodactyly 2 | 110
Broad forehead 2 | 59
Broad hallux 2 | 29
Cancer 2 | 2,499
Congenital diaphragmatic hernia 2 | 67
Curvature of little finger 2 | 110
Curvature of spine 2 | 282
Dental caries 2 | 164
Downward slant of palpebral fissure 2 | 158
Hypoplastic mandible condyle 2 | 275
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Progressive relapsing multiple sclerosis 2 | 19
Rhabdomyosarcoma 2 | 39
Rotting teeth 2 | 73
Telecanthus 2 | 62
Uranostaphyloschisis 2 | 167
acute quadriplegic myopathy 2 | 1,158
invasive ductal carcinoma 2 | 2,951
medulloblastoma, large-cell 2 | 6,241
22q11 Deletion Syndrome 1 | 10
22q11 partial monosomy syndrome 1 | 9
22q11.2 deletion syndrome 1 | 8
Abnormality of aortic arch 1 | 9
Abnormality of the endocrine system 1 | 9
Abnormality of the tonsils 1 | 10
Atrioventricular Septal Defect 1 | 22
CONOTRUNCAL ANOMALY FACE SYNDROME 1 | 9
Cervical polyp 1 | 4
Cholelithiasis 1 | 33
Chromosome 22Q11.2 Duplication Syndrome 1 | 1
Chromosome 6pter-p24 deletion syndrome 1 | 4
Cleft uvula 1 | 27
Congenital absence of parathyroid gland 1 | 2
Congenital ear anomaly NOS (disorder) 1 | 29
Congenital hypoplasia of radius 1 | 23
Corneal Neovascularization 1 | 13
Coronal hypospadias 1 | 4
Dacryocystitis 1 | 11
Delayed eruption of primary teeth 1 | 10
Double Outlet Right Ventricle 1 | 11
Dysphasia 1 | 23
Ectomesenchymoma 1 | 5
Endocrine System Diseases 1 | 11
Familial hemophagocytic lymphohistiocytosis 1 1 | 11
Hand deformities 1 | 32
Hearing Loss, Mixed Conductive-Sensorineural 1 | 12
Hemophagocytic lymphohistiocytosis 1 | 30
Hernia, Femoral 1 | 7
Hernias, Diaphragmatic, Congenital 1 | 17
Hypernasal voice 1 | 39
Hypoplastic lobules 1 | 11
Impaired T cell function 1 | 14
Interrupted aortic arch 1 | 4
Intestinal atresia 1 | 12
Lacrimal Duct Obstruction 1 | 16
Middle ear abnormalities 1 | 2
Mild Mental Retardation 1 | 70
Muscle Cramp 1 | 55
Muscular Dystrophy, Duchenne 1 | 7
Myalgia 1 | 54
Myopathies, Structural, Congenital 1 | 15
Myopathy, Centronuclear, Autosomal Dominant 1 | 5
Nasal voice 1 | 39
Obstruction of nasolacrimal duct 1 | 9
Occipital myelomeningocele 1 | 8
Overfolded helix 1 | 24
POLYDACTYLY, POSTAXIAL 1 | 13
Paranoia 1 | 20
Parathyroid hypoplasia 1 | 3
Partial duplication of thumb phalanx 1 | 6
Persistant truncus arteriosus 1 | 17
Pierre Robin Syndrome 1 | 11
Platybasia 1 | 13
Pseudosarcomatous fibromatosis 1 | 8
Radial polydactyly 1 | 8
Radial ray hypoplasia 1 | 23
Rhabdomyosarcoma, Embryonal 1 | 5
Right aortic arch with mirror image branching 1 | 5
Short ulnae 1 | 24
Shprintzen syndrome 1 | 9
Simple syndactyly of fingers - first web 1 | 9
Small thymus 1 | 13
Subcoronal hypospadias 1 | 4
Tetany 1 | 18
Thin hypoplastic alae nasi 1 | 51
Tietz syndrome 1 | 6
Tortuous retinal vessels 1 | 15
ULNAR HYPOPLASIA 1 | 24
Unilateral primary pulmonary dysgenesis 1 | 5
Velopharyngeal Insufficiency 1 | 8
Velopharyngeal dysfunction 1 | 8
Xerostomia 1 | 42
esophageal atresia/tracheoesophageal fistula 1 | 22

Tissue

Digestive Tract 6 | 17,369
Male tissues 6 | 17,142
Skin and soft tissues 6 | 17,230
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Blood and immune system 3 | 16,909
Nervous System 3 | 16,725
Urinary Tract 3 | 16,678
Cardiovascular System 2 | 15,192
Liver and Pancreas 2 | 16,750
Respiratory system 2 | 16,393

Target Family

Transcription Factor 5 | 1,400
Non-IDG 1 | 12,091

GO Process

muscle cell fate commitment 6 | 6
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
Myogenin MYOG Tbio Transcription Factor -2.97963 827.3 659
Myoblast determination protein 1 MYOD1 Tbio Transcription Factor -3.16910 1355.7 632
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.55166 363.0 320
Myogenic factor 5 MYF5 Tbio Transcription Factor -2.51865 298.8 320
Myogenic factor 6 MYF6 Tbio Transcription Factor -2.08811 111.3 176