Development Level

Tbio 56 | 11,445
Tchem 12 | 1,598
Tclin 9 | 613
Tdark 5 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal bone structure 3 | 187
embryonic lethality prior to t... 3 | 278
increased startle reflex 3 | 112
abnormal behavior 2 | 298
abnormal embryo development 2 | 7
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 38
decreased circulating amylase ... 2 | 28
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased mean corpuscular hem... 2 | 96
increased or absent threshold ... 2 | 101
increased spleen weight 2 | 10
short tibia 2 | 97
small testis 2 | 58
abnormal bone mineralization 1 | 38
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal locomotor behavior 1 | 24
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal testis morphology 1 | 43
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased spleen weight 1 | 10
edema 1 | 59
enlarged epididymis 1 | 31
enlarged kidney 1 | 14
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
mammalian phenotype 1 | 17
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499
small spleen 1 | 19
thrombocytosis 1 | 27

Disease

Carcinoma 66 | 11,493
ovarian cancer 50 | 8,520
osteosarcoma 40 | 7,950
psoriasis 40 | 6,694
medulloblastoma, large-cell 37 | 6,241
atypical teratoid / rhabdoid tumor 35 | 5,112
glioblastoma 34 | 5,792
Cancer 32 | 2,499
Breast cancer 28 | 3,578
ependymoma 28 | 4,679
lung cancer 27 | 4,740
Kidney cancer 25 | 2,613
group 3 medulloblastoma 25 | 4,104
adult high grade glioma 24 | 3,801
pancreatic cancer 22 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
malignant mesothelioma 21 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
lung adenocarcinoma 19 | 2,716
non-small cell lung cancer 19 | 2,890
Short stature 18 | 531
Intellectual disability 17 | 1,016
lung carcinoma 17 | 2,843
astrocytic glioma 16 | 2,597
group 4 medulloblastoma 16 | 1,855
invasive ductal carcinoma 16 | 2,951
oligodendroglioma 16 | 2,850
primitive neuroectodermal tumor 16 | 3,035
Schizophrenia 15 | 1,160
Astrocytoma, Pilocytic 14 | 3,081
Autosomal recessive predisposition 14 | 1,442
Epilepsy 14 | 792
Pick disease 14 | 1,894
pituitary cancer 14 | 1,972
subependymal giant cell astrocytoma 14 | 2,287
ulcerative colitis 14 | 1,819
Cognitive delay 13 | 608
Cryptorchidism 13 | 296
Dull intelligence 13 | 645
Global developmental delay 13 | 608
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental and motor retardation 13 | 608
Mental deficiency 13 | 645
Poor school performance 13 | 645
adrenocortical carcinoma 13 | 1,428
Muscle hypotonia 12 | 571
breast carcinoma 12 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
tuberculosis 12 | 2,010
Liver cancer 11 | 604
Seizures 11 | 596
primary pancreatic ductal adenocarcinoma 11 | 1,109
Hypoplastic mandible condyle 10 | 275
Mandibular hypoplasia 10 | 275
Micrognathism 10 | 275
Small head 10 | 374
Strabismus 10 | 270
diabetes mellitus 10 | 1,728
spina bifida 10 | 1,074
Broad flat nasal bridge 9 | 236
Feeding difficulties in infancy 9 | 175
Hypogonadism 9 | 173
Nasal bridge wide 9 | 236
acute quadriplegic myopathy 9 | 1,158
cutaneous lupus erythematosus 9 | 1,057
cystic fibrosis 9 | 1,696
interstitial cystitis 9 | 2,312
Autistic Disorder 8 | 364
Breast Neoplasms 8 | 445
Congenital hypoplasia of penis 8 | 176
Down syndrome 8 | 499
Mammary Neoplasms 8 | 425
Orbital separation excessive 8 | 244
Sensorineural Hearing Loss (disorder) 8 | 284
colon cancer 8 | 1,478
ductal carcinoma in situ 8 | 1,745
hepatocellular carcinoma 8 | 547
juvenile dermatomyositis 8 | 1,187
non primary Sjogren syndrome sicca 8 | 891
Acquired scoliosis 7 | 281
Atopic dermatitis 7 | 952
Bipolar Disorder 7 | 666
Blepharoptosis 7 | 231
Curvature of spine 7 | 282
Fetal Growth Retardation 7 | 189
Infant, Small for Gestational Age 7 | 176
Intrauterine retardation 7 | 176
Melanoma 7 | 711
Rheumatoid arthritis 7 | 1,191
Short neck 7 | 140
astrocytoma 7 | 1,146
gastric carcinoma 7 | 807
Alzheimer's disease 6 | 658
Failure to gain weight 6 | 365
Multiple myeloma 6 | 1,332
fibroadenoma 6 | 559
gastric cancer 6 | 459
pancreatic carcinoma 6 | 562

Tissue

Endocrine System 80 | 18,159
Female tissues 80 | 17,400
Skin and soft tissues 79 | 17,230
Blood and immune system 78 | 16,909
Digestive Tract 78 | 17,369
Liver and Pancreas 78 | 16,750
Nervous System 78 | 16,725
Urinary Tract 78 | 16,678
Male tissues 77 | 17,142
Respiratory system 77 | 16,393
Cardiovascular System 71 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 17 | 4,145
Transcription Factor 12 | 1,400
Kinase 6 | 634
Nuclear Receptor 4 | 48
Transporter 4 | 473
Epigenetic 2 | 242
GPCR 1 | 408
Ion Channel 1 | 344

GO Process

multicellular organism growth 82 | 82
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Krueppel-like factor 2 KLF2 Tbio Transcription Factor -2.30630 216.2 308
Selenoprotein M SELENOM Tdark Non-IDG -1.51502 30.3 0
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.11308 129.3 11
Feline leukemia virus subgroup C receptor-related protein 1 FLVCR1 Tbio Non-IDG -1.54460 33.8 139
SLIT and NTRK-like protein 1 SLITRK1 Tbio Non-IDG -2.74906 555.5 206
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Hairy and enhancer of split-related protein HELT HELT Tbio Transcription Factor -1.41399 26.4 85
Double-stranded RNA-specific editase 1 ADARB1 Tbio Enzyme -2.08959 118.0 103
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97
Spectrin beta chain, non-erythrocytic 2 SPTBN2 Tbio Non-IDG -1.73436 53.8 237