Development Level

Tbio 330 | 11,445
Tdark 83 | 6,588
Tchem 35 | 1,598
Tclin 12 | 613

Collection

Kinase: IDG Consortium (Comple... 5 | 37
RFA-RM-18-021 5 | 328
Kinase: IDG Consortium (Target... 4 | 125
GPCR: IDG Consortium (Complete... 2 | 25
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 26 | 979
preweaning lethality, incomple... 12 | 499
abnormal embryo size 11 | 220
abnormal behavior 9 | 298
abnormal heart morphology 9 | 162
embryonic lethality prior to t... 9 | 278
enlarged heart 9 | 210
increased bone mineral content 9 | 108
embryonic lethality prior to o... 7 | 239
decreased vertical activity 6 | 208
hyperactivity 6 | 148
increased circulating alkaline... 6 | 122
decreased prepulse inhibition 5 | 82
decreased total body fat amoun... 5 | 207
male infertility 5 | 123
thrombocytopenia 5 | 56
abnormal gait 4 | 69
abnormal kidney morphology 4 | 65
abnormal seminal vesicle morph... 4 | 114
decreased circulating glucose ... 4 | 126
decreased circulating triglyce... 4 | 79
decreased grip strength 4 | 116
decreased leukocyte cell numbe... 4 | 73
decreased mean corpuscular vol... 4 | 79
female infertility 4 | 60
hypoactivity 4 | 132
increased lean body mass 4 | 172
increased startle reflex 4 | 112
abnormal bone structure 3 | 187
abnormal neural tube closure 3 | 46
abnormal skin morphology 3 | 50
cataract 3 | 92
decreased hemoglobin content 3 | 68
decreased lean body mass 3 | 135
improved glucose tolerance 3 | 79
increased bone mineral density 3 | 72
increased erythrocyte cell num... 3 | 39
increased lymphocyte cell numb... 3 | 32
increased mean corpuscular hem... 3 | 96
increased total body fat amoun... 3 | 134
abnormal behavioral response t... 2 | 66
abnormal coat- hair morphology 2 | 19
abnormal eye morphology 2 | 68
abnormal forebrain development 2 | 20
abnormal hindbrain development 2 | 16
abnormal lens morphology 2 | 81
abnormal midbrain development 2 | 20
abnormal sleep behavior 2 | 70
abnormal spinal cord morpholog... 2 | 9
abnormal spleen morphology 2 | 55
abnormal tail morphology 2 | 25
decreased T cell number 2 | 15
decreased blood urea nitrogen ... 2 | 51
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating LDL chol... 2 | 38
decreased circulating alkaline... 2 | 46
decreased circulating chloride... 2 | 30
decreased circulating choleste... 2 | 93
decreased circulating iron lev... 2 | 32
decreased food intake 2 | 13
decreased heart left ventricle... 2 | 28
decreased heart weight 2 | 27
decreased hematocrit 2 | 46
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
decreased red blood cell distr... 2 | 41
decreased respiratory quotient 2 | 16
decreased startle reflex 2 | 75
edema 2 | 59
embryonic growth retardation 2 | 106
enlarged lymph nodes 2 | 37
increased circulating HDL chol... 2 | 80
increased circulating potassiu... 2 | 29
increased circulating total pr... 2 | 28
increased circulating triglyce... 2 | 42
increased fasted circulating g... 2 | 76
increased grip strength 2 | 41
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
limb grasping 2 | 41
pale yolk sac 2 | 25
polycystic kidney 2 | 15
prenatal lethality prior to he... 2 | 87
tremors 2 | 39
abnormal optic disc morphology 1 | 10
decreased IgG1 level 1 | 8
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
enlarged ovary 1 | 2
increased cardiac muscle contr... 1 | 8
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
microphthalmia 1 | 26
thin ventricular wall 1 | 24

Disease

Carcinoma 297 | 11,493
ovarian cancer 196 | 8,520
osteosarcoma 195 | 7,950
psoriasis 174 | 6,694
medulloblastoma, large-cell 152 | 6,241
glioblastoma 134 | 5,792
lung cancer 125 | 4,740
group 3 medulloblastoma 113 | 4,104
atypical teratoid / rhabdoid tumor 110 | 5,112
ependymoma 105 | 4,679
Cancer 104 | 2,499
malignant mesothelioma 95 | 3,232
Breast cancer 94 | 3,578
Kidney cancer 91 | 2,613
adult high grade glioma 88 | 3,801
Astrocytoma, Pilocytic 83 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 79 | 3,291
non-small cell lung cancer 79 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 74 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 73 | 2,989
invasive ductal carcinoma 73 | 2,951
pancreatic cancer 71 | 2,398
lung carcinoma 70 | 2,843
primitive neuroectodermal tumor 68 | 3,035
interstitial cystitis 67 | 2,312
lung adenocarcinoma 66 | 2,716
oligodendroglioma 59 | 2,850
cystic fibrosis 58 | 1,696
tuberculosis 58 | 2,010
pituitary cancer 57 | 1,972
ulcerative colitis 54 | 1,819
subependymal giant cell astrocytoma 50 | 2,287
astrocytic glioma 48 | 2,597
ductal carcinoma in situ 47 | 1,745
breast carcinoma 45 | 1,638
Rheumatoid arthritis 41 | 1,191
Infertility 39 | 188
colon cancer 39 | 1,478
cutaneous lupus erythematosus 39 | 1,057
group 4 medulloblastoma 39 | 1,855
Autosomal recessive predisposition 37 | 1,442
Pick disease 36 | 1,894
adrenocortical carcinoma 36 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 34 | 1,962
Male infertility 33 | 206
juvenile dermatomyositis 31 | 1,187
diabetes mellitus 29 | 1,728
Melanoma 28 | 711
gastric carcinoma 28 | 807
nasopharyngeal carcinoma 27 | 1,058
primary pancreatic ductal adenocarcinoma 26 | 1,109
active Crohn's disease 25 | 922
pediatric high grade glioma 25 | 1,064
Schizophrenia 24 | 1,160
spina bifida 24 | 1,074
Intellectual disability 23 | 1,016
Short stature 23 | 531
acute quadriplegic myopathy 23 | 1,158
astrocytoma 23 | 1,146
dermatomyositis 23 | 966
Multiple myeloma 22 | 1,332
Duchenne muscular dystrophy 21 | 601
Liver cancer 21 | 604
Atopic dermatitis 20 | 952
Cleft Palate 20 | 271
Endometriosis 20 | 540
Skin cancer 20 | 469
Cryptorchidism 19 | 296
esophageal adenocarcinoma 19 | 737
pancreatic carcinoma 19 | 562
Liver Cirrhosis, Experimental 18 | 769
acute myeloid leukemia 18 | 783
hepatocellular carcinoma 18 | 547
Acquired scoliosis 17 | 281
Breast Neoplasms 17 | 445
Cognitive delay 17 | 608
Curvature of spine 17 | 282
Global developmental delay 17 | 608
Mammary Neoplasms 17 | 425
Mental and motor retardation 17 | 608
active ulcerative colitis 17 | 764
chronic rhinosinusitis 17 | 512
primary Sjogren syndrome 17 | 735
urothelial carcinoma 17 | 318
Broad flat nasal bridge 16 | 236
Down syndrome 16 | 499
Hypoplastic mandible condyle 16 | 275
Mandibular hypoplasia 16 | 275
Micrognathism 16 | 275
Nasal bridge wide 16 | 236
Obesity 16 | 678
autosomal dominant Emery-Dreifuss muscular dystrophy 16 | 510
fibroadenoma 16 | 559
Alzheimer's disease 15 | 658
Kidney disease 15 | 430
Prostatic Neoplasms 15 | 495
Uranostaphyloschisis 15 | 167
head and neck cancer 15 | 271
medulloblastoma 15 | 720
Mental Retardation 14 | 645

Tissue

Endocrine System 448 | 18,159
Digestive Tract 421 | 17,369
Female tissues 416 | 17,400
Skin and soft tissues 413 | 17,230
Male tissues 410 | 17,142
Blood and immune system 408 | 16,909
Urinary Tract 395 | 16,678
Nervous System 392 | 16,725
Liver and Pancreas 388 | 16,750
Respiratory system 388 | 16,393
Cardiovascular System 344 | 15,192

Target Family

Non-IDG 271 | 12,091
Transcription Factor 98 | 1,400
Enzyme 40 | 4,145
Kinase 25 | 634
Epigenetic 8 | 242
GPCR 8 | 408
Ion Channel 5 | 344
Transporter 5 | 473

GO Process

multicellular organism develop... 460 | 460
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Speedy protein A SPDYA Tbio Non-IDG -1.58097 42.8 145
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
Lens epithelial cell protein LEP503 LENEP Tdark Non-IDG -0.79588 6.85 10
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 ASZ1 Tbio Non-IDG -2.81661 644.9 107
ATP-dependent DNA helicase Q4 RECQL4 Tbio Enzyme 0.00000 0
T-complex protein 11 homolog TCP11 Tbio Non-IDG -1.26152 18.0 80
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 SOHLH2 Tbio Transcription Factor -1.26578 21.4 126
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
Membrane progestin receptor alpha PAQR7 Tbio Non-IDG -1.89212 76.1 122
Uncharacterized protein ZSWIM9 ZSWIM9 Tdark Non-IDG 0.00000 12