Development Level

Tbio 310 | 10,625
Tdark 94 | 7,003
Tchem 41 | 1,890
Tclin 11 | 602

Collection

Eligible Kinase Proteins 4 | 134
Eligible Ion Channel Proteins 2 | 117

IMPC Term

preweaning lethality, complete... 14 | 633
preweaning lethality, incomple... 9 | 260
abnormal embryo size 7 | 112
decreased circulating glucose ... 5 | 121
abnormal behavior 4 | 226
decreased grip strength 4 | 123
embryonic lethality prior to t... 4 | 187
increased mean corpuscular vol... 4 | 91
abnormal forebrain development 3 | 18
abnormal gait 3 | 51
abnormal heart morphology 3 | 51
abnormal hindbrain development 3 | 24
abnormal midbrain development 3 | 22
abnormal neural tube closure 3 | 37
decreased body weight 3 | 174
enlarged heart 3 | 111
increased bone mineral content 3 | 92
increased circulating alkaline... 3 | 119
increased mean corpuscular hem... 3 | 93
increased total body fat amoun... 3 | 57
abnormal bone structure 2 | 131
abnormal coat/ hair morphology 2 | 18
abnormal eye morphology 2 | 38
abnormal posture 2 | 5
abnormal seminal vesicle morph... 2 | 47
abnormal spinal cord morpholog... 2 | 8
abnormal spleen morphology 2 | 36
absent heartbeat 2 | 6
anophthalmia 2 | 20
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 37
decreased circulating alkaline... 2 | 41
decreased circulating chloride... 2 | 32
decreased circulating choleste... 2 | 85
decreased circulating triglyce... 2 | 83
decreased hemoglobin content 2 | 53
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
enlarged lymph nodes 2 | 27
hydrops fetalis 2 | 22
hyperactivity 2 | 108
hypoactivity 2 | 89
increased bone mineral density 2 | 52
increased circulating calcium ... 2 | 32
increased circulating serum al... 2 | 25
increased circulating total pr... 2 | 20
increased exploration in new e... 2 | 56
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased lean body mass 2 | 107
increased rib number 2 | 41
pale yolk sac 2 | 12
prenatal lethality prior to he... 2 | 64
thrombocytopenia 2 | 46
tremors 2 | 34
abnormal behavioral response t... 1 | 52
abnormal epididymis morphology 1 | 31
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal lymph node morphology 1 | 3
abnormal skin morphology 1 | 23
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 21
decreased CD4-positive, alpha ... 1 | 19
decreased IgG1 level 1 | 4
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased heart rate 1 | 10
decreased hematocrit 1 | 25
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased threshold for audito... 1 | 32
female infertility 1 | 34
increased CD4-positive, CD25-p... 1 | 18
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased erythrocyte cell num... 1 | 26
increased startle reflex 1 | 38
lethargy 1 | 5
limb grasping 1 | 35
polycystic kidney 1 | 9
prolonged RR interval 1 | 2
short tail 1 | 4
short tibia 1 | 82
small testis 1 | 37

Disease

ovarian cancer 195 | 8,492
osteosarcoma 193 | 7,933
psoriasis 172 | 6,685
medulloblastoma, large-cell 149 | 6,234
glioblastoma 123 | 5,572
lung cancer 111 | 4,473
atypical teratoid / rhabdoid tumor 91 | 4,369
Cancer 89 | 2,346
malignant mesothelioma 87 | 3,163
Breast cancer 81 | 3,099
pilocytic astrocytoma 80 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 78 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 76 | 2,956
invasive ductal carcinoma 75 | 2,950
non-small cell lung cancer 75 | 2,798
Carcinoma 74 | 2,147
intraductal papillary-mucinous carcinoma (IPMC) 74 | 2,988
lung carcinoma 73 | 2,844
pancreatic cancer 70 | 2,300
primitive neuroectodermal tumor 67 | 3,031
interstitial cystitis 65 | 2,299
lung adenocarcinoma 64 | 2,714
pediatric high grade glioma 63 | 2,712
cystic fibrosis 58 | 1,670
oligodendroglioma 58 | 2,849
ulcerative colitis 58 | 2,087
ependymoma 55 | 2,514
pituitary cancer 54 | 1,972
group 3 medulloblastoma 53 | 2,254
group 4 medulloblastoma 52 | 1,875
tuberculosis 50 | 1,563
ductal carcinoma in situ 47 | 1,745
subependymal giant cell astrocytoma 47 | 2,287
breast carcinoma 45 | 1,614
astrocytic glioma 44 | 2,241
adult high grade glioma 43 | 2,148
Rheumatoid Arthritis 39 | 1,171
sonic hedgehog group medulloblastoma 39 | 1,482
Pick disease 37 | 1,893
cutaneous lupus erythematosus 37 | 1,056
Infertility 36 | 163
adrenocortical carcinoma 36 | 1,427
posterior fossa group B ependymoma 36 | 1,530
primary pancreatic ductal adenocarcinoma 35 | 1,271
colon cancer 33 | 1,475
gastric carcinoma 32 | 832
medulloblastoma 32 | 1,524
juvenile dermatomyositis 31 | 1,189
posterior fossa group A ependymoma 30 | 1,511
Male infertility 29 | 170
diabetes mellitus 29 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 28 | 1,795
astrocytoma 27 | 1,493
dermatomyositis 26 | 967
active Crohn's disease 25 | 918
nasopharyngeal carcinoma 25 | 1,056
Duchenne muscular dystrophy 23 | 602
acute quadriplegic myopathy 23 | 1,157
atypical teratoid/rhabdoid tumor 22 | 1,095
spina bifida 22 | 1,064
Multiple myeloma 21 | 1,328
esophageal adenocarcinoma 21 | 737
pancreatic carcinoma 21 | 567
Atopic dermatitis 20 | 944
Endometriosis 20 | 535
chronic rhinosinusitis 19 | 512
fibroadenoma 19 | 557
hepatocellular carcinoma 19 | 550
acute myeloid leukemia 18 | 785
Down syndrome 17 | 548
autosomal dominant Emery-Dreifuss muscular dystrophy 16 | 499
urothelial carcinoma 16 | 318
Obesity 15 | 616
Polycystic Ovary Syndrome 15 | 335
primary Sjogren syndrome 15 | 789
Alzheimer's disease 14 | 644
Mammary Neoplasms 14 | 410
Prostatic Neoplasms 14 | 471
Schizophrenia 14 | 503
Waldenstrons macroglobulinemia 14 | 765
head and neck cancer 14 | 270
non primary Sjogren syndrome sicca 14 | 840
Kidney disease 13 | 397
Peripheral Neuropathy 12 | 303
active ulcerative colitis 12 | 477
tuberculosis and treatment for 6 months 12 | 686
Acquired metabolic disease 11 | 267
Azoospermia 11 | 89
Craniofacial Abnormalities 11 | 147
Hypersensitivity reaction type II disease 11 | 235
aldosterone-producing adenoma 11 | 664
Asthma 10 | 349
Crohn's disease 10 | 304
chronic lymphosyte leukemia 10 | 232
gastric cancer 10 | 436
mucosa-associated lymphoid tissue lymphoma 10 | 480
Intellectual disability 9 | 573
Multiple Sclerosis 9 | 498
chronic lymphocytic leukemia 9 | 244
periodontitis 9 | 269

Tissue

Endocrine System 447 | 18,512
Female tissues 445 | 18,647
Digestive Tract 444 | 18,473
Nervous System 441 | 18,561
Male tissues 440 | 17,969
Urinary Tract 439 | 18,444
Skin and soft tissues 437 | 18,115
Liver and Pancreas 434 | 18,136
Cardiovascular System 431 | 17,958
Blood and immune system 427 | 17,995
Respiratory system 414 | 17,484

Target Family

Non-IDG 275 | 11,969
Transcription Factor 98 | 1,400
Enzyme 38 | 4,146
Kinase 19 | 634
Epigenetic 8 | 242
GPCR 8 | 408
Ion Channel 5 | 341
Transporter 5 | 473

GO Process

multicellular organism develop... 456 | 456
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NACHT, LRR and PYD domains-containing protein 14 NLRP14 Tbio Non-IDG -1.33032 17.6 30
Thioredoxin domain-containing protein 2 TXNDC2 Tbio Non-IDG -0.71996 6.88 13
Thioredoxin reductase 3 TXNRD3 Tchem Enzyme -1.69637 55.1 0
Homeobox protein Nkx-3.1 NKX3-1 Tbio Transcription Factor -2.10264 130.3 456
MORC family CW-type zinc finger protein 1 MORC1 Tbio Non-IDG -1.72150 49.2 59
Gametogenetin GGN Tbio Non-IDG -2.09870 121.9 53
Protein boule-like BOLL Tbio Non-IDG -1.83799 68.3 370
Protein dopey-2 DOPEY2 Tbio Non-IDG -0.67912 6.04 14
Paired mesoderm homeobox protein 2 PRRX2 Tbio Transcription Factor -0.73611 6.19 114
Tesmin TESMIN Tbio Non-IDG -1.20276 16.3 87