Development Level

Tbio 56 | 11,445
Tchem 15 | 1,598
Tclin 7 | 613
Tdark 2 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal seminal vesicle morph... 2 | 114
decreased body weight 2 | 161
decreased circulating creatini... 2 | 39
decreased circulating fructosa... 2 | 30
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased mean corpuscular hem... 2 | 96
abnormal coat-hair pigmentatio... 1 | 64
abnormal colon morphology 1 | 3
abnormal cornea morphology 1 | 31
abnormal heart morphology 1 | 162
abnormal ileum morphology 1 | 2
abnormal iris morphology 1 | 13
abnormal iris pigmentation 1 | 4
abnormal locomotor activation 1 | 16
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
absent urinary bladder 1 | 1
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased lactate dehydrogenas... 1 | 16
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
fusion of vertebral arches 1 | 7
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased circulating chloride... 1 | 41
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased granulocyte number 1 | 1
increased heart rate 1 | 23
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged RR interval 1 | 8
shortened RR interval 1 | 17
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 54 | 11,493
ovarian cancer 50 | 8,520
glioblastoma 40 | 5,792
psoriasis 38 | 6,694
osteosarcoma 37 | 7,950
Cancer 36 | 2,499
lung cancer 34 | 4,740
medulloblastoma, large-cell 30 | 6,241
atypical teratoid / rhabdoid tumor 29 | 5,112
pancreatic cancer 29 | 2,398
ependymoma 25 | 4,679
interstitial cystitis 23 | 2,312
Astrocytoma, Pilocytic 22 | 3,081
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
lung carcinoma 22 | 2,843
invasive ductal carcinoma 21 | 2,951
ulcerative colitis 21 | 1,819
Breast cancer 20 | 3,578
adult high grade glioma 20 | 3,801
malignant mesothelioma 20 | 3,232
tuberculosis 19 | 2,010
diabetes mellitus 17 | 1,728
lung adenocarcinoma 17 | 2,716
Rheumatoid arthritis 16 | 1,191
juvenile dermatomyositis 16 | 1,187
non-small cell lung cancer 16 | 2,890
oligodendroglioma 16 | 2,850
cystic fibrosis 15 | 1,696
group 3 medulloblastoma 15 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Multiple myeloma 14 | 1,332
colon cancer 14 | 1,478
primitive neuroectodermal tumor 14 | 3,035
subependymal giant cell astrocytoma 14 | 2,287
Duchenne muscular dystrophy 13 | 601
astrocytic glioma 13 | 2,597
group 4 medulloblastoma 13 | 1,855
Liver Cirrhosis, Experimental 12 | 769
Waldenstrons macroglobulinemia 12 | 765
acute quadriplegic myopathy 12 | 1,158
astrocytoma 12 | 1,146
breast carcinoma 12 | 1,638
dermatomyositis 12 | 966
pediatric high grade glioma 12 | 1,064
Arthritis 11 | 290
adrenocortical carcinoma 11 | 1,428
esophageal adenocarcinoma 11 | 737
pituitary cancer 11 | 1,972
primary pancreatic ductal adenocarcinoma 11 | 1,109
Alzheimer's disease 10 | 658
Asthma 10 | 385
Inflammation 10 | 120
Pick disease 10 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
ductal carcinoma in situ 10 | 1,745
primary Sjogren syndrome 10 | 735
Breast Neoplasms 9 | 445
Depressive disorder 9 | 409
Mammary Neoplasms 9 | 425
Multiple Sclerosis 9 | 540
Neoplasm Metastasis 9 | 168
Schizophrenia 9 | 1,160
acute myeloid leukemia 9 | 783
nasopharyngeal carcinoma 9 | 1,058
Atherosclerosis 8 | 291
Lung disease 8 | 142
Mental Depression 8 | 333
Obesity 8 | 678
Prostatic Neoplasms 8 | 495
Vascular disease 8 | 319
cutaneous lupus erythematosus 8 | 1,057
gastric cancer 8 | 459
medulloblastoma 8 | 720
mucosa-associated lymphoid tissue lymphoma 8 | 484
pancreatic carcinoma 8 | 562
spina bifida 8 | 1,074
Animal Mammary Neoplasms 7 | 136
Atopic dermatitis 7 | 952
Bipolar Disorder 7 | 666
Human immunodeficiency virus infectious disease 7 | 138
Inflammatory bowel disease 7 | 151
Kidney cancer 7 | 2,613
Kidney disease 7 | 430
Liver disease 7 | 237
Malaria 7 | 160
Mammary Neoplasms, Animal 7 | 136
Mammary Neoplasms, Experimental 7 | 154
Osteoporosis 7 | 363
hepatocellular carcinoma 7 | 547
Arthritis, Juvenile 6 | 126
Crohn's disease 6 | 321
Dermatitis 6 | 157
Hypersensitivity reaction type II disease 6 | 253
Hypertension 6 | 396
Juvenile arthritis 6 | 126
Myocardial Ischemia 6 | 169
fibroadenoma 6 | 559
periodontitis 6 | 293

Tissue

Endocrine System 80 | 18,159
Blood and immune system 78 | 16,909
Digestive Tract 78 | 17,369
Liver and Pancreas 78 | 16,750
Respiratory system 78 | 16,393
Skin and soft tissues 78 | 17,230
Female tissues 77 | 17,400
Male tissues 77 | 17,142
Nervous System 77 | 16,725
Urinary Tract 77 | 16,678
Cardiovascular System 73 | 15,192

Target Family

Non-IDG 52 | 12,091
Enzyme 13 | 4,145
GPCR 8 | 408
Kinase 5 | 634
Transcription Factor 1 | 1,400
oGPCR 1 | 421

GO Process

movement of cell or subcellula... 80 | 80
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Tropomyosin alpha-4 chain TPM4 Tbio Non-IDG -1.57899 37.4 120
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
E3 ubiquitin-protein ligase AMFR AMFR Tbio Enzyme -2.46909 292.8 203
N-formyl peptide receptor 3 FPR3 Tchem GPCR -1.41613 24.4 247
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Heat shock protein beta-1 HSPB1 Tchem Non-IDG -2.97780 974.9 1992
Metastasis suppressor protein 1 MTSS1 Tbio Non-IDG -2.73880 551.8 126
Rho GDP-dissociation inhibitor 1 ARHGDIA Tchem Non-IDG -2.56885 370.1 382
Rho GDP-dissociation inhibitor 2 ARHGDIB Tbio Non-IDG -1.93968 99.3 358