Development Level

Tbio 19 | 11,445
Tdark 4 | 6,588

IMPC Phenotype

abnormal behavior 2 | 298
increased lymphocyte cell numb... 2 | 32
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal nail morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating glucose ... 1 | 24
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
male infertility 1 | 123
thrombocytopenia 1 | 56

Disease

Carcinoma 16 | 11,493
ependymoma 16 | 4,679
Primary ciliary dyskinesia 10 | 76
Situs Inversus 9 | 65
chronic rhinosinusitis 8 | 512
medulloblastoma, large-cell 8 | 6,241
ovarian cancer 8 | 8,520
Ciliary Motility Disorders 7 | 38
Kartagener Syndrome 7 | 38
atypical teratoid / rhabdoid tumor 7 | 5,112
nasopharyngeal carcinoma 7 | 1,058
Breast cancer 6 | 3,578
Ciliary Dyskinesia, Primary, 1 6 | 27
lung adenocarcinoma 6 | 2,716
glioblastoma 5 | 5,792
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
osteosarcoma 5 | 7,950
Autosomal recessive predisposition 4 | 1,442
Bronchiectasis 4 | 64
Intellectual disability 4 | 1,016
Polydactyly 4 | 107
cystic fibrosis and chronic rhinosinusitis 4 | 214
group 3 medulloblastoma 4 | 4,104
Dextrocardia 3 | 12
Hydrocephalus 3 | 152
Infertility 3 | 188
Male infertility 3 | 206
Recurrent otitis media 3 | 42
Recurrent respiratory infections 3 | 141
Sinusitis 3 | 65
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
Bardet-Biedl syndrome 2 | 51
Bardet-Biedl syndrome 1 2 | 22
Becker muscular dystrophy 2 | 191
Bronchitis, Chronic 2 | 12
Duchenne muscular dystrophy 2 | 601
Dull intelligence 2 | 645
Fundus dystrophy 2 | 83
Gastrointestinal Stromal Tumors 2 | 48
Joubert syndrome 2 | 66
Kidney cancer 2 | 2,613
Low intelligence 2 | 645
Meckel syndrome 2 | 46
Meckel-Gruber syndrome 2 | 13
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Muscle hypotonia 2 | 571
Nasal Polyps 2 | 10
Nasal inflammation 2 | 7
Nephronophthisis 2 | 80
Obesity 2 | 678
Paranasal Sinus Diseases 2 | 34
Polycystic ovary syndrome 2 | 360
Poor school performance 2 | 645
Recurrent sinus disease 2 | 22
Recurrent sinusitis 2 | 22
Respiratory insufficiency due to defective ciliary clearance 2 | 6
Rhinitis 2 | 54
Senior-Loken syndrome 2 | 22
Situs ambiguus 2 | 25
adult high grade glioma 2 | 3,801
atypical teratoid/rhabdoid tumor 2 | 357
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
tuberculosis 2 | 2,010
Beta thalassemia 1 | 16
Cardiac conduction abnormalities 1 | 78
Cardiomegaly 1 | 116
Cardiomyopathies 1 | 110
Childhood onset 1 | 38
Ciliopathy 1 | 71
Cone dystrophy 1 | 71
Disease of anatomical entity 1 | 32
EKG abnormalities 1 | 78
Electrocardiogram change 1 | 78
Ellis-Van Creveld syndrome 1 | 19
Fatigue 1 | 182
Lymphoid leukemia 1 | 160
Muscle Weakness 1 | 170
Muscular Dystrophies 1 | 8
Necrosis 1 | 53
Neoplasm Metastasis 1 | 168
Pervasive developmental disorder 1 | 9
Prostate carcinoma in situ 1 | 11
Respiratory Failure 1 | 104
Urine color abnormal 1 | 6
X- linked recessive 1 | 110
non-small cell lung carcinoma 1 | 317

Tissue

Endocrine System 23 | 18,159
Digestive Tract 22 | 17,369
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Blood and immune system 21 | 16,909
Male tissues 21 | 17,142
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Nervous System 20 | 16,725
Urinary Tract 20 | 16,678
Cardiovascular System 18 | 15,192

Target Family

Non-IDG 19 | 12,091
Transcription Factor 3 | 1,400
Enzyme 1 | 4,145

GO Process

motile cilium assembly 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dynein assembly factor 3, axonemal DNAAF3 Tbio Non-IDG -0.88461 7.47 0
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
Basal body-orientation factor 1 BBOF1 Tdark Non-IDG 0.30 0.89 26
Multicilin MCIDAS Tbio Non-IDG -2.06596 109.5 75
Homeobox protein notochord NOTO Tdark Transcription Factor -2.36366 209.2 26
Zinc finger MYND domain-containing protein 10 ZMYND10 Tbio Non-IDG -0.91444 10.1 158
Dynein assembly factor 1, axonemal DNAAF1 Tbio Non-IDG -1.03493 11.7 85
Coiled-coil and C2 domain-containing protein 2A CC2D2A Tbio Non-IDG -1.23748 18.2 17
A-kinase anchor protein 4 AKAP4 Tbio Enzyme -1.95952 93.1 116
Cilia- and flagella-associated protein 221 CFAP221 Tdark Non-IDG -0.71620 4.48 46