Development Level

Tbio 9 | 11,445
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
abnormal behavior 1 | 298
decreased bone mineral density 1 | 126
enlarged heart 1 | 210
increased circulating choleste... 1 | 66
increased circulating glycerol... 1 | 9

Disease

Carcinoma 7 | 11,493
ovarian cancer 7 | 8,520
Breast cancer 5 | 3,578
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
lung cancer 5 | 4,740
oligodendroglioma 5 | 2,850
psoriasis 5 | 6,694
Schizophrenia 4 | 1,160
breast carcinoma 4 | 1,638
malignant mesothelioma 4 | 3,232
Astrocytoma, Pilocytic 3 | 3,081
Breast Neoplasms 3 | 445
Cancer 3 | 2,499
Kidney cancer 3 | 2,613
Mammary Neoplasms 3 | 425
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
osteosarcoma 3 | 7,950
Anteverted nostril 2 | 191
Autosomal recessive predisposition 2 | 1,442
Blepharoptosis 2 | 231
Cleft Lip 2 | 141
Cleft Palate 2 | 271
Cognitive delay 2 | 608
Congenital Heart Defects 2 | 58
Congenital heart disease 2 | 93
Craniofacial Abnormalities 2 | 151
Down syndrome 2 | 499
Epilepsy 2 | 792
Global developmental delay 2 | 608
Highly variable severity 2 | 157
Liver cancer 2 | 604
Long philtrum 2 | 137
Mental and motor retardation 2 | 608
Prostate cancer 2 | 175
Prostatic Neoplasms 2 | 495
Seizures 2 | 596
Short nose 2 | 132
Small nose 2 | 132
Syndactyly 2 | 88
Variable expressivity 2 | 157
active ulcerative colitis 2 | 764
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
medulloblastoma 2 | 720
medulloblastoma, large-cell 2 | 6,241
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
spina bifida 2 | 1,074
Abnormality of the nasopharynx 1 | 9
Absence of Stensen duct 1 | 4
Absence of the parotid gland 1 | 3
Agenesis of punctum lacrimale 1 | 4
Alacrima 1 | 9
Anomalous tracheal cartilage 1 | 2
Arachnoid Cysts 1 | 5
Beta-cell dysfunction 1 | 5
Blepharospasm 1 | 13
Burns, Chemical 1 | 6
CLEFT CHIN 1 | 9
Congenital hypoplasia of pancreas 1 | 2
Contracture of lower limb 1 | 6
Craniofacial dysostosis type 1 1 | 2
Crouzon Syndrome 1 | 3
DIABETES MELLITUS, PERMANENT NEONATAL 1 | 5
Dextraposition of aorta 1 | 3
Distal 10q deletion syndrome 1 | 5
ECTODERMAL DYSPLASIA 12, HYPOHIDROTIC/HAIR/TOOTH/NAIL TYPE 1 | 1
Hennekam syndrome 1 | 7
High urine albumin levels 1 | 5
Hypoplastic lacrimal duct 1 | 3
Hypoplastic lacrimal gland 1 | 3
Iridocele 1 | 3
Ketonuria 1 | 8
LADD syndrome 1 | 9
Lacrimal Puncta, Absence of 1 | 4
Lacrimoauriculodentodigital syndrome 1 | 3
MATURITY-ONSET DIABETES OF THE YOUNG, TYPE IV (disorder) 1 | 1
Maturity-Onset Diabetes of the Young, Type 4 1 | 1
Microalbuminuria 1 | 5
Multiple suture craniosynostosis 1 | 2
Neonatal insulin-dependent diabetes mellitus 1 | 6
Overriding aorta 1 | 3
PANCREATIC AGENESIS 1 1 | 2
Pancreatic Agenesis, Congenital 1 | 2
Parotid gland hypoplasia 1 | 3
Synostosis of carpal bones 1 | 9
Thenar hypoplasia 1 | 4

Tissue

Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Female tissues 8 | 17,400
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

morphogenesis of embryonic epi... 10 | 10
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G-rich sequence factor 1 GRSF1 Tbio Non-IDG -1.05585 12.0 138
Retinal dehydrogenase 2 ALDH1A2 Tbio Enzyme -2.25078 175.3 229
Keratinocyte differentiation factor 1 KDF1 Tbio Non-IDG -0.26977 2.27 78
Pancreas/duodenum homeobox protein 1 PDX1 Tbio Transcription Factor -2.36445 252.7 605
Transforming growth factor beta-1-induced transcript 1 protein TGFB1I1 Tbio Non-IDG -1.82580 89.7 147
Protocadherin-8 PCDH8 Tbio Non-IDG -2.22282 170.9 95
Vascular endothelial growth factor C VEGFC Tbio Non-IDG -2.99495 1028.1 667
Laminin subunit alpha-5 LAMA5 Tbio Non-IDG -1.43472 26.4 217
Fibroblast growth factor receptor 2 FGFR2 Tclin Kinase -3.08664 1210.6 948
Protein jagged-2 JAG2 Tbio Non-IDG -2.56606 327.5 353