Development Level

Tbio 8 | 11,445

IMPC Phenotype

decreased body length 2 | 101
preweaning lethality, complete... 2 | 979

Disease

Carcinoma 5 | 11,493
Molybdenum Cofactor Deficiency, Complementation Group A 4 | 4
medulloblastoma, large-cell 4 | 6,241
osteosarcoma 4 | 7,950
Autosomal recessive predisposition 3 | 1,442
Combined molybdoflavoprotein enzyme deficiency 3 | 3
Xanthinuria 3 | 10
ductal carcinoma in situ 3 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Axonal loss 2 | 7
Big calvaria 2 | 147
Cerebral atrophy 2 | 178
Chubby cheeks 2 | 50
Degenerative brain disorder 2 | 100
Dilated ventricles (finding) 2 | 121
Ectopia Lentis 2 | 17
Encephalomalacia 2 | 3
Epilepsy 2 | 792
Feeding difficulties 2 | 127
Frontal bossing 2 | 157
Full cheeks 2 | 50
Gliosis 2 | 56
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hyperplasia of cheeks 2 | 50
Hypertrophy of cheeks 2 | 50
Hypoplasia of corpus callosum 2 | 90
Hypouricemia 2 | 5
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Increased urinary hypoxanthine 2 | 2
Increased urinary taurine 2 | 2
Intellectual disability 2 | 1,016
Long face 2 | 71
Long philtrum 2 | 137
Molybdenum Cofactor Deficiency, Complementation Group B 2 | 2
Myoclonic spasms 2 | 2
Nystagmus 2 | 317
Opisthotonus 2 | 14
Orbital separation excessive 2 | 244
Peripheral demyelination 2 | 16
Pick disease 2 | 1,894
Poor growth 2 | 114
Progressive disorder 2 | 142
Puffy cheeks 2 | 50
Seizures 2 | 596
Short nose 2 | 132
Small head 2 | 374
Small nose 2 | 132
Spastic Quadriplegia 2 | 42
Supratentorial atrophy 2 | 94
Thick vermilion border 2 | 25
Very poor growth 2 | 114
Xanthine stones 2 | 3
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
ovarian cancer 2 | 8,520
Alcoholic Intoxication, Chronic 1 | 289
Alcoholism 1 | 45
Alzheimer's disease 1 | 658
Autism spectrum disorder 1 | 101
Axial hypotonia 1 | 46
CHARGE syndrome 1 | 26
Choanal Atresia 1 | 42
Cocaine-Related Disorders 1 | 92
Duane-radial ray syndrome 1 | 8
Exaggerated startle response 1 | 8
Friedreich ataxia 1 | 24
Hernia, Inguinal 1 | 89
Hyperexplexia 1 | 8
Hyperreflexia 1 | 209
Hypokinesia 1 | 19
Infantile onset 1 | 238
Muscle Hypertonia 1 | 88
Myoclonus 1 | 74
Polymicrogyria 1 | 48
Poor eye contact 1 | 12
Poor head control 1 | 14
Pulmonary aspiration 1 | 8
Spontaneous abortion 1 | 113
Stiff-Person syndrome 1 | 12
Thyroid cancer 1 | 36
Tonic - clonic seizures 1 | 44
Umbilical hernia 1 | 93
cystic fibrosis 1 | 1,696
hereditary spastic paraplegia 1 | 318
medulloblastoma 1 | 720
pediatric high grade glioma 1 | 1,064
sarcoidosis 1 | 370
tuberculosis 1 | 2,010
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 3 | 12,091

GO Process

molybdopterin cofactor biosynt... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cysteine desulfurase, mitochondrial NFS1 Tbio Enzyme -1.70267 46.3 131
Molybdenum cofactor biosynthesis protein 1 MOCS1 Tbio Non-IDG -1.28570 20.9 138
Molybdopterin synthase catalytic subunit MOCS2 Tbio Enzyme -2.05483 207.6 92
Molybdenum cofactor sulfurase MOCOS Tbio Enzyme -1.10485 13.1 28
Gephyrin GPHN Tbio Non-IDG -2.56617 383.9 235
MAP3K12-binding inhibitory protein 1 MBIP Tbio Non-IDG -0.82976 5.94 78
Molybdopterin synthase sulfur carrier subunit MOCS2 Tbio Enzyme -2.05483 207.6 92
Adenylyltransferase and sulfurtransferase MOCS3 MOCS3 Tbio Enzyme -1.08678 10.9 128