Development Level

Tbio 22 | 11,445
Tchem 8 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
cataract 3 | 92
abnormal lens morphology 2 | 81
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal retina morphology 1 | 71
cardiovascular system phenotyp... 1 | 36
decreased bone mineral content 1 | 151
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
female infertility 1 | 60
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
sclerocornea 1 | 2
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 28 | 8,520
Carcinoma 27 | 11,493
osteosarcoma 22 | 7,950
lung cancer 20 | 4,740
glioblastoma 18 | 5,792
psoriasis 18 | 6,694
medulloblastoma, large-cell 17 | 6,241
group 3 medulloblastoma 16 | 4,104
Breast cancer 15 | 3,578
adult high grade glioma 15 | 3,801
atypical teratoid / rhabdoid tumor 15 | 5,112
non-small cell lung cancer 15 | 2,890
invasive ductal carcinoma 14 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
adrenocortical carcinoma 12 | 1,428
ductal carcinoma in situ 12 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
lung adenocarcinoma 12 | 2,716
malignant mesothelioma 12 | 3,232
primitive neuroectodermal tumor 12 | 3,035
Cancer 11 | 2,499
colon cancer 11 | 1,478
Atopic dermatitis 10 | 952
nasopharyngeal carcinoma 10 | 1,058
Astrocytoma, Pilocytic 9 | 3,081
Intellectual disability 9 | 1,016
Kidney cancer 9 | 2,613
Small head 9 | 374
ependymoma 9 | 4,679
Microcephaly 8 | 166
Autosomal recessive predisposition 7 | 1,442
Dull intelligence 7 | 645
Endometriosis 7 | 540
Epilepsy 7 | 792
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
astrocytic glioma 7 | 2,597
oligodendroglioma 7 | 2,850
pancreatic cancer 7 | 2,398
Seizures 6 | 596
Short stature 6 | 531
breast carcinoma 6 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung carcinoma 6 | 2,843
pituitary cancer 6 | 1,972
posterior fossa group A ependymoma 6 | 468
Cognitive delay 5 | 608
Delayed bone age 5 | 136
Global developmental delay 5 | 608
Mental and motor retardation 5 | 608
primary Sjogren syndrome 5 | 735
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Dilated ventricles (finding) 4 | 121
Downward slant of palpebral fissure 4 | 158
Hypoplastic mandible condyle 4 | 275
Mammary Neoplasms, Experimental 4 | 154
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Pick disease 4 | 1,894
Sloping forehead 4 | 46
diabetes mellitus 4 | 1,728
esophageal adenocarcinoma 4 | 737
interstitial cystitis 4 | 2,312
non primary Sjogren syndrome sicca 4 | 891
Animal Mammary Neoplasms 3 | 136
Bilateral fifth finger clinodactyly 3 | 110
Bulging forehead 3 | 66
Cachexia 3 | 50
Concave bridge of nose 3 | 195
Curvature of little finger 3 | 110
Defective tooth enamel 3 | 31
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Duchenne muscular dystrophy 3 | 601
Dystrophic tooth enamel 3 | 31
Enamel abnormalities 3 | 31
Fetal Growth Retardation 3 | 189
Hyperplasia of nose 3 | 23
Hypertrophy of nose 3 | 23
Hypoplastic feet 3 | 66
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Large nose 3 | 23
Lissencephaly 3 | 69
Long philtrum 3 | 137
Low set ears 3 | 181
Mammary Neoplasms, Animal 3 | 136
Multiple myeloma 3 | 1,332
Pachygyria 3 | 41
Prominent forehead 3 | 66
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
chronic rhinosinusitis 3 | 512
cutaneous lupus erythematosus 3 | 1,057
juvenile dermatomyositis 3 | 1,187
pediatric high grade glioma 3 | 1,064
spina bifida 3 | 1,074

Tissue

Blood and immune system 33 | 16,909
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678
Cardiovascular System 32 | 15,192

Target Family

Non-IDG 27 | 12,091
Kinase 3 | 634
Enzyme 2 | 4,145
Transcription Factor 1 | 1,400

GO Process

mitotic spindle organization 33 | 33
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrator complex subunit 13 INTS13 Tdark Non-IDG -1.21861 15.4 36
Ribosome maturation protein SBDS SBDS Tbio Non-IDG -2.24233 174.4 139
Kinesin-like protein KIF11 KIF11 Tchem Non-IDG -2.61375 404.4 300
WD repeat-containing protein 62 WDR62 Tbio Non-IDG -1.43806 35.5 33
Microtubule-associated protein 4 MAP4 Tbio Non-IDG -2.27689 185.8 253
Cytoplasmic dynein 1 heavy chain 1 DYNC1H1 Tbio Non-IDG -1.80946 62.1 94
Centromere-associated protein E CENPE Tchem Non-IDG -2.14817 140.2 166
Dual specificity protein kinase TTK TTK Tchem Kinase -2.33639 219.1 336
Centrosomal protein of 126 kDa CEP126 Tdark Non-IDG -0.32736 2.12 15
SCL-interrupting locus protein STIL Tbio Non-IDG -1.99386 94.6 49