Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
preweaning lethality, complete... 2 | 979
abnormal craniofacial morpholo... 1 | 33
decreased circulating glucose ... 1 | 126
embryonic growth retardation 1 | 106
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 8 | 11,493
medulloblastoma, large-cell 8 | 6,241
ovarian cancer 8 | 8,520
psoriasis 8 | 6,694
group 3 medulloblastoma 6 | 4,104
osteosarcoma 6 | 7,950
Breast cancer 5 | 3,578
Kidney cancer 5 | 2,613
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
glioblastoma 5 | 5,792
primitive neuroectodermal tumor 5 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
oligodendroglioma 4 | 2,850
Cornelia de Lange syndrome 3 | 21
Dull intelligence 3 | 645
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Waldenstrons macroglobulinemia 3 | 765
ependymoma 3 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
Abnormal behavior 2 | 52
Absent auditory canals 2 | 23
Absent external auditory canals 2 | 23
Anteverted nostril 2 | 191
Anxiety 2 | 136
Anxiety disease 2 | 113
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Atresia of the external auditory canal 2 | 23
Atretic auditory canal 2 | 23
Attention deficit hyperactivity disorder 2 | 278
Bilateral fifth finger clinodactyly 2 | 110
Bilateral single transverse palmar creases 2 | 34
Blepharoptosis 2 | 231
Bowed and upward slanting eyebrows 2 | 41
Brachycephaly 2 | 88
Broad cranium shape 2 | 88
Bushy eyebrows 2 | 49
Byzanthine arch palate 2 | 194
Concave bridge of nose 2 | 195
Conductive hearing loss 2 | 123
Curvature of little finger 2 | 110
Cutis marmorata 2 | 32
Delayed bone age 2 | 136
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Failure to gain weight 2 | 365
Gastroesophageal reflux disease 2 | 110
Generalized hirsutism 2 | 36
Heartburn 2 | 78
Hirsutism 2 | 47
Hypoplasia of nipple 2 | 16
Hypoplastic feet 2 | 66
Joint stiffness 2 | 84
Late tooth eruption 2 | 61
Long eyelashes 2 | 37
Long philtrum 2 | 137
Low posterior hairline 2 | 52
Microcephaly 2 | 166
Micromelia 2 | 58
Muscle Hypertonia 2 | 88
Myopia 2 | 176
Obsessive compulsive behavior 2 | 25
Pediatric failure to thrive 2 | 365
Penile hypospadias 2 | 106
Premature Birth 2 | 77
Premature birth of newborn 2 | 67
Radioulnar synostosis 2 | 35
Roberts syndrome 2 | 15
Sensorineural Hearing Loss (disorder) 2 | 284
Severe mental retardation (I.Q. 20-34) 2 | 99
Short nose 2 | 132
Sleep disturbances 2 | 37
Small hand 2 | 36
Small nose 2 | 132
Speech Disorders 2 | 58
Syndactyly of the toes 2 | 45
Synophrys 2 | 40
Thick, flared eyebrows 2 | 41
Thin lips 2 | 49
Thin upper lip vermilion 2 | 67
Vesico-Ureteral Reflux 2 | 33
Wide skull shape 2 | 88
Widely spaced teeth 2 | 31
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
non-small cell lung cancer 2 | 2,890
obsessive-compulsive disorder 2 | 61
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Non-IDG 10 | 12,091
Kinase 1 | 634

GO Process

mitotic sister chromatid cohes... 11 | 11
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Chromosome transmission fidelity protein 8 homolog CHTF8 Tbio Non-IDG 0.00000 10
Chromosome transmission fidelity protein 8 homolog isoform 2 CHTF8 Tdark Non-IDG 0.00000 10
Pogo transposable element with ZNF domain POGZ Tbio Non-IDG -0.97046 8.51 102
Structural maintenance of chromosomes protein 1A SMC1A Tbio Non-IDG -1.84148 64.7 686
Cell division cycle protein 20 homolog CDC20 Tbio Non-IDG -2.60409 401.5 393
Nipped-B-like protein NIPBL Tbio Non-IDG -2.25874 186.3 134
Sister chromatid cohesion protein PDS5 homolog B PDS5B Tbio Non-IDG -2.56388 363.0 103
Sister chromatid cohesion protein PDS5 homolog A PDS5A Tbio Non-IDG -1.71103 53.7 172
Wings apart-like protein homolog WAPL Tbio Non-IDG -2.39021 215.2 125
Serine/threonine-protein kinase haspin HASPIN Tchem Kinase -1.70391 50.0 120