Development Level

Tbio 32 | 11,651
Tchem 3 | 1,388

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to o... 4 | 239
abnormal embryo size 3 | 220
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
abnormal behavior 2 | 298
abnormal embryo turning 2 | 31
increased circulating chloride... 2 | 41
abnormal body wall morphology 1 | 9
abnormal craniofacial morpholo... 1 | 33
abnormal heart looping 1 | 5
abnormal heart morphology 1 | 162
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal skin coloration 1 | 25
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
cataract 1 | 92
decreased circulating chloride... 1 | 30
decreased heart left ventricle... 1 | 28
decreased red blood cell distr... 1 | 41
enlarged spleen 1 | 41
hyperactivity 1 | 148
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
protruding tongue 1 | 3
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 25 | 8,520
lung cancer 16 | 4,740
medulloblastoma, large-cell 16 | 6,241
psoriasis 15 | 6,694
Carcinoma 14 | 11,493
group 3 medulloblastoma 14 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
atypical teratoid / rhabdoid tumor 13 | 5,112
adult high grade glioma 12 | 3,801
Breast cancer 11 | 3,578
glioblastoma 11 | 5,792
malignant mesothelioma 11 | 3,232
non-small cell lung cancer 11 | 2,890
osteosarcoma 11 | 7,950
adrenocortical carcinoma 10 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
primitive neuroectodermal tumor 10 | 3,035
invasive ductal carcinoma 9 | 2,951
Atopic dermatitis 8 | 952
Cancer 8 | 2,499
dermatomyositis 7 | 966
lung adenocarcinoma 7 | 2,716
colon cancer 6 | 1,478
ductal carcinoma in situ 6 | 1,745
ependymoma 6 | 4,679
Endometriosis 5 | 540
Multiple myeloma 5 | 1,332
Autosomal recessive predisposition 4 | 1,442
Neurodegenerative disease 4 | 414
Waldenstrons macroglobulinemia 4 | 765
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
pancreatic cancer 4 | 2,398
primary Sjogren syndrome 4 | 735
Cerebellar Hypoplasia 3 | 61
Dull intelligence 3 | 645
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Muscle Spasticity 3 | 195
Pick disease 3 | 1,894
Poor school performance 3 | 645
acute quadriplegic myopathy 3 | 1,158
interstitial cystitis 3 | 2,312
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Amyotrophic lateral sclerosis 2 | 451
Astrocytoma, Pilocytic 2 | 3,081
Bipolar Disorder 2 | 666
Cognitive delay 2 | 608
Deglutition Disorders 2 | 132
Dystonia 2 | 164
Dystonic disease 2 | 106
Fetal Growth Retardation 2 | 189
Global developmental delay 2 | 608
Hip Dislocation, Congenital 2 | 48
Hyperreflexia 2 | 209
Infant, Small for Gestational Age 2 | 176
Intrauterine retardation 2 | 176
Joint hyperflexibility 2 | 78
Mental and motor retardation 2 | 608
Multiple Sclerosis 2 | 540
Poor speech 2 | 37
Problems speaking 2 | 37
Roberts syndrome 2 | 15
Seckel syndrome 2 | 34
Short stature 2 | 531
Sloping forehead 2 | 46
Small head 2 | 374
Vascular disease 2 | 319
astrocytoma 2 | 1,146
diabetes mellitus 2 | 1,728
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
juvenile dermatomyositis 2 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
Apathy 1 | 16
Apraxias 1 | 27
Enlarged thorax 1 | 18
Irritation - emotion 1 | 68
Laryngotracheomalacia 1 | 1
Metaphyseal irregularity 1 | 23
Platyspondyly 1 | 56
Postnatal microcephaly 1 | 24
Precociously senile appearance 1 | 18
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Respiratory insufficiency due to muscle weakness 1 | 37
Restlessness 1 | 14
Spondyloepimetaphyseal disorder 1 | 9
Spondyloepimetaphyseal dysplasia 1 | 12

Tissue

Blood and immune system 35 | 16,909
Digestive Tract 35 | 17,369
Endocrine System 35 | 18,159
Female tissues 35 | 17,400
Liver and Pancreas 35 | 16,750
Male tissues 35 | 17,142
Nervous System 35 | 16,725
Respiratory system 35 | 16,393
Skin and soft tissues 35 | 17,230
Urinary Tract 35 | 16,678
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 33 | 12,091
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

GO Process

mitotic metaphase plate congre... 35 | 35
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Importin subunit beta-1 KPNB1 Tbio Non-IDG -1.63038 38.8 174
Kinesin-like protein KIF22 KIF22 Tbio Non-IDG -1.69996 54.3 147
Centromere/kinetochore protein zw10 homolog ZW10 Tbio Non-IDG -1.64269 41.5 124
Charged multivesicular body protein 5 CHMP5 Tbio Non-IDG -1.35804 24.3 157
Vacuolar protein sorting-associated protein 4A VPS4A Tbio Non-IDG -1.69610 49.5 94
Charged multivesicular body protein 2a CHMP2A Tbio Non-IDG -2.45155 278.6 88
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.65458 432.1 352
Nuclear pore glycoprotein p62 NUP62 Tbio Non-IDG -1.80390 62.5 241
Borealin CDCA8 Tbio Non-IDG -1.60291 37.6 299
Cullin-3 CUL3 Tbio Non-IDG -3.26322 1670.8 307