Development Level

Tbio 36 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 4 | 499
embryonic lethality prior to o... 3 | 239
decreased body weight 2 | 161
increased circulating HDL chol... 2 | 80
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal skin coloration 1 | 25
cardiovascular system phenotyp... 1 | 36
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hemorrhage 1 | 23
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased heart rate variabili... 1 | 7
increased mean corpuscular vol... 1 | 92
prenatal lethality prior to he... 1 | 87
tremors 1 | 39

Disease

ovarian cancer 33 | 8,520
Carcinoma 27 | 11,493
glioblastoma 25 | 5,792
lung cancer 23 | 4,740
medulloblastoma, large-cell 22 | 6,241
ependymoma 21 | 4,679
group 3 medulloblastoma 21 | 4,104
Breast cancer 20 | 3,578
atypical teratoid / rhabdoid tumor 19 | 5,112
psoriasis 19 | 6,694
adult high grade glioma 18 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
non-small cell lung cancer 17 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
invasive ductal carcinoma 16 | 2,951
pancreatic cancer 16 | 2,398
ductal carcinoma in situ 15 | 1,745
lung adenocarcinoma 15 | 2,716
primitive neuroectodermal tumor 15 | 3,035
adrenocortical carcinoma 14 | 1,428
breast carcinoma 14 | 1,638
malignant mesothelioma 13 | 3,232
oligodendroglioma 13 | 2,850
osteosarcoma 13 | 7,950
Astrocytoma, Pilocytic 12 | 3,081
Atopic dermatitis 11 | 952
Kidney cancer 11 | 2,613
colon cancer 11 | 1,478
nasopharyngeal carcinoma 10 | 1,058
ulcerative colitis 10 | 1,819
Cancer 9 | 2,499
Endometriosis 9 | 540
Pick disease 9 | 1,894
subependymal giant cell astrocytoma 9 | 2,287
Liver cancer 7 | 604
astrocytic glioma 7 | 2,597
diabetes mellitus 7 | 1,728
pituitary cancer 7 | 1,972
primary pancreatic ductal adenocarcinoma 7 | 1,109
Intellectual disability 6 | 1,016
acute quadriplegic myopathy 6 | 1,158
astrocytoma 6 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
juvenile dermatomyositis 6 | 1,187
primary Sjogren syndrome 6 | 735
active Crohn's disease 5 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
chronic rhinosinusitis 5 | 512
lung carcinoma 5 | 2,843
tuberculosis and treatment for 6 months 5 | 409
Autosomal recessive predisposition 4 | 1,442
Dull intelligence 4 | 645
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Polycystic ovary syndrome 4 | 360
Poor school performance 4 | 645
Waldenstrons macroglobulinemia 4 | 765
esophageal adenocarcinoma 4 | 737
group 4 medulloblastoma 4 | 1,855
hepatocellular carcinoma 4 | 547
Animal Mammary Neoplasms 3 | 136
Autistic Disorder 3 | 364
Breast Neoplasms 3 | 445
Chronic Lymphocytic Leukemia 3 | 262
Duchenne muscular dystrophy 3 | 601
Endometrial cancer 3 | 311
Epilepsy 3 | 792
Mammary Neoplasms 3 | 425
Mammary Neoplasms, Animal 3 | 136
Microcephaly 3 | 166
Multiple myeloma 3 | 1,332
Retinitis Pigmentosa 3 | 226
Short stature 3 | 531
cystic fibrosis and chronic rhinosinusitis 3 | 214
dermatomyositis 3 | 966
medulloblastoma 3 | 720
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
tuberculosis 3 | 2,010
Adenoma 2 | 167
Aggressive behavior 2 | 75
Aggressive reaction 2 | 75
Depressive disorder 2 | 409
Down syndrome 2 | 499
Failure to gain weight 2 | 365
Hyperreflexia 2 | 209
Lung Neoplasms 2 | 232
Melanoma 2 | 711
Pediatric failure to thrive 2 | 365
Physical aggression 2 | 76
Prostatic Neoplasms 2 | 495
Schizophrenia 2 | 1,160
Seizures 2 | 596
Skin cancer 2 | 469
acute myeloid leukemia 2 | 783
aldosterone-producing adenoma 2 | 665
cystic fibrosis 2 | 1,696
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074

Tissue

Endocrine System 40 | 18,159
Blood and immune system 39 | 16,909
Cardiovascular System 39 | 15,192
Digestive Tract 39 | 17,369
Female tissues 39 | 17,400
Liver and Pancreas 39 | 16,750
Male tissues 39 | 17,142
Nervous System 39 | 16,725
Respiratory system 39 | 16,393
Skin and soft tissues 39 | 17,230
Urinary Tract 39 | 16,678

Target Family

Non-IDG 31 | 12,091
Enzyme 7 | 4,145
Kinase 2 | 634

GO Process

mitotic cytokinesis 40 | 40
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Sorting nexin-18 SNX18 Tbio Non-IDG -0.76724 7.20 156
MIT domain-containing protein 1 MITD1 Tbio Non-IDG -0.25556 2.10 59
Sorting nexin-33 SNX33 Tbio Non-IDG -0.49386 3.94 99
Programmed cell death 6-interacting protein PDCD6IP Tbio Non-IDG -1.59404 35.1 216
Cytoskeleton-associated protein 2 CKAP2 Tbio Non-IDG -2.30784 205.9 84
Cullin-7 CUL7 Tbio Non-IDG -1.49747 38.0 139
Centrosomal protein of 55 kDa CEP55 Tbio Non-IDG -1.49634 36.2 207
Talanin ZNF365 Tbio Non-IDG -1.44015 50.6 273
Ankyrin-3 ANK3 Tbio Non-IDG -2.25280 172.9 170