Development Level

Tbio 15 | 11,445

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal craniofacial morpholo... 1 | 33
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating chloride... 1 | 41

Disease

ovarian cancer 12 | 8,520
Carcinoma 10 | 11,493
group 3 medulloblastoma 10 | 4,104
atypical teratoid / rhabdoid tumor 9 | 5,112
lung cancer 9 | 4,740
medulloblastoma, large-cell 9 | 6,241
osteosarcoma 9 | 7,950
adult high grade glioma 8 | 3,801
glioblastoma 8 | 5,792
non-small cell lung cancer 8 | 2,890
primitive neuroectodermal tumor 8 | 3,035
psoriasis 8 | 6,694
Breast cancer 7 | 3,578
adrenocortical carcinoma 7 | 1,428
lung adenocarcinoma 7 | 2,716
malignant mesothelioma 7 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
Atopic dermatitis 5 | 952
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
ependymoma 5 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
Kidney cancer 4 | 2,613
colon cancer 4 | 1,478
nasopharyngeal carcinoma 4 | 1,058
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary Sjogren syndrome 3 | 735
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Endometriosis 2 | 540
Prenatal onset 2 | 139
Waldenstrons macroglobulinemia 2 | 765
astrocytoma 2 | 1,146
interstitial cystitis 2 | 2,312
oligodendroglioma 2 | 2,850
progressive supranuclear palsy 2 | 676
Absent speech 1 | 43
Adult onset 1 | 82
Arrhythmogenic right ventricular cardiomyopathy 1 | 30
Astigmatism 1 | 54
Axial hypotonia 1 | 46
Bell Palsy 1 | 58
Blepharoptosis 1 | 231
Cardiac Arrhythmia 1 | 103
Cardiac conduction abnormalities 1 | 78
Cardiomyopathy 1 | 116
Centronuclear myopathy 1 | 27
Childhood onset 1 | 38
Colorectal Neoplasms 1 | 243
Conduction disorder of the heart 1 | 79
Congenital clubfoot 1 | 109
Congenital pes cavus 1 | 88
DOID:2627 1 | 94
DOID:9917 1 | 31
Dilated cardiomyopathy 1 | 56
Distal limb muscle weakness due to peripheral neuropathy 1 | 62
EKG abnormalities 1 | 78
ENSP00000256078 1 | 30
Electrocardiogram abnormal 1 | 81
Electrocardiogram change 1 | 78
Esotropia 1 | 31
Facial Paresis 1 | 59
Facial muscle weakness of muscles innervated by CN VII 1 | 58
Generalized muscle weakness 1 | 57
Heart conduction disease 1 | 83
Hyperopia 1 | 70
Hypertrichosis 1 | 46
Hypertrophic Cardiomyopathy 1 | 117
Hypoplasia of corpus callosum 1 | 90
Hypoplasia of the brainstem 1 | 22
Infantile onset 1 | 238
Large intestine cancer 1 | 126
Liver Cirrhosis, Experimental 1 | 769
Lymphoid leukemia 1 | 160
Motor delay 1 | 147
Muscle Weakness 1 | 170
Muscle biopsy shows dystrophic changes 1 | 39
Muscular Diseases 1 | 27
Muscular dystrophy 1 | 75
Myopia 1 | 176
No development of motor milestones 1 | 147
Paget's disease of bone 1 | 36
Pontocerebellar hypoplasia 1 | 36
Poor speech 1 | 37
Problems speaking 1 | 37
Proximal muscle weakness 1 | 47
Proximal neurogenic muscle weakness 1 | 47
Respiratory Failure 1 | 104
Roberts syndrome 1 | 15
Slow progression 1 | 89
Xeroderma pigmentosum variant type 1 | 4
cystic fibrosis and chronic rhinosinusitis 1 | 214
hereditary spastic paraplegia 1 | 318
limb-girdle muscular dystrophy 1 | 37
non-small cell lung carcinoma 1 | 317
nonverbal 1 | 43
posterior fossa group A ependymoma 1 | 468
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Non-IDG 9 | 12,091
Enzyme 3 | 4,145
Epigenetic 2 | 242
Kinase 1 | 634

GO Process

mitotic chromosome condensatio... 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Charged multivesicular body protein 1a CHMP1A Tbio Non-IDG -1.15571 14.9 161
Titin TTN Tbio Kinase -3.24415 1743.0 123
A-kinase anchor protein 8-like AKAP8L Tbio Enzyme -1.03730 13.2 140
A-kinase anchor protein 8 AKAP8 Tbio Enzyme -1.38531 25.2 264
Condensin complex subunit 2 NCAPH Tbio Non-IDG -1.54249 35.6 257
Condensin complex subunit 1 NCAPD2 Tbio Non-IDG -1.15845 13.0 109
Structural maintenance of chromosomes protein 2 SMC2 Tbio Non-IDG -0.69216 5.13 188
Structural maintenance of chromosomes protein 4 SMC4 Tbio Non-IDG -1.49520 28.0 167
Condensin-2 complex subunit D3 NCAPD3 Tbio Non-IDG -1.18079 14.7 141
Nucleolar and spindle-associated protein 1 NUSAP1 Tbio Non-IDG -1.48322 31.1 179