Development Level

Tbio 71 | 11,445
Tchem 18 | 1,598
Tdark 4 | 6,588
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 4 | 125
Kinase: IDG Consortium (Comple... 2 | 37
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 13 | 979
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 5 | 278
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
decreased bone mineral content 3 | 151
decreased lean body mass 3 | 135
increased circulating HDL chol... 3 | 80
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal embryo size 2 | 220
decreased body length 2 | 101
decreased body weight 2 | 161
decreased bone mineral density 2 | 126
decreased mean corpuscular hem... 2 | 50
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
hypoactivity 2 | 132
increased leukocyte cell numbe... 2 | 47
increased total body fat amoun... 2 | 134
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
thrombocytopenia 2 | 56
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal rib morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
abnormal skin coloration 1 | 25
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased cardiac muscle contr... 1 | 11
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating chloride... 1 | 41
increased circulating creatini... 1 | 38
increased circulating thyroxin... 1 | 7
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
sclerocornea 1 | 2
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 68 | 11,493
ovarian cancer 60 | 8,520
medulloblastoma, large-cell 49 | 6,241
osteosarcoma 46 | 7,950
psoriasis 44 | 6,694
Breast cancer 43 | 3,578
glioblastoma 42 | 5,792
group 3 medulloblastoma 41 | 4,104
atypical teratoid / rhabdoid tumor 40 | 5,112
lung cancer 35 | 4,740
primitive neuroectodermal tumor 35 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
lung adenocarcinoma 30 | 2,716
adult high grade glioma 29 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
non-small cell lung cancer 29 | 2,890
invasive ductal carcinoma 27 | 2,951
Cancer 26 | 2,499
ependymoma 26 | 4,679
malignant mesothelioma 26 | 3,232
adrenocortical carcinoma 25 | 1,428
breast carcinoma 22 | 1,638
Atopic dermatitis 20 | 952
ductal carcinoma in situ 19 | 1,745
colon cancer 17 | 1,478
nasopharyngeal carcinoma 17 | 1,058
Endometriosis 16 | 540
oligodendroglioma 16 | 2,850
pancreatic cancer 16 | 2,398
Kidney cancer 15 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
astrocytic glioma 12 | 2,597
Astrocytoma, Pilocytic 11 | 3,081
Multiple myeloma 11 | 1,332
Pick disease 11 | 1,894
interstitial cystitis 11 | 2,312
pediatric high grade glioma 11 | 1,064
tuberculosis 11 | 2,010
Rheumatoid arthritis 10 | 1,191
pituitary cancer 10 | 1,972
subependymal giant cell astrocytoma 10 | 2,287
ulcerative colitis 10 | 1,819
group 4 medulloblastoma 9 | 1,855
Small head 8 | 374
Autosomal recessive predisposition 7 | 1,442
dermatomyositis 7 | 966
Breast Neoplasms 6 | 445
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Intellectual disability 6 | 1,016
Mammary Neoplasms 6 | 425
Mental and motor retardation 6 | 608
Short stature 6 | 531
Waldenstrons macroglobulinemia 6 | 765
astrocytoma 6 | 1,146
diabetes mellitus 6 | 1,728
esophageal adenocarcinoma 6 | 737
juvenile dermatomyositis 6 | 1,187
posterior fossa group B ependymoma 6 | 416
primary Sjogren syndrome 6 | 735
progressive supranuclear palsy 6 | 676
Anteverted nostril 5 | 191
Dull intelligence 5 | 645
Hypoplastic mandible condyle 5 | 275
Liver cancer 5 | 604
Low intelligence 5 | 645
Mandibular hypoplasia 5 | 275
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Microcephaly 5 | 166
Micrognathism 5 | 275
Neurodegenerative disease 5 | 414
Poor school performance 5 | 645
aldosterone-producing adenoma 5 | 665
gastric carcinoma 5 | 807
lung carcinoma 5 | 2,843
non primary Sjogren syndrome sicca 5 | 891
non-small cell lung carcinoma 5 | 317
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
spina bifida 5 | 1,074
Bipolar Disorder 4 | 666
Concave bridge of nose 4 | 195
Congenital hypoplasia of penis 4 | 176
Depressed nasal bridge 4 | 195
Depressed nasal root/bridge 4 | 195
Fetal Growth Retardation 4 | 189
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Keratoconus 4 | 113
Long philtrum 4 | 137
Lymphoid leukemia 4 | 160
Seckel syndrome 4 | 34
Type 2 diabetes mellitus 4 | 272
acute quadriplegic myopathy 4 | 1,158
medulloblastoma 4 | 720
primary pancreatic ductal adenocarcinoma 4 | 1,109
Crohn's disease 3 | 321
Glaucoma 3 | 239
Immune system cancer 3 | 140
cutaneous lupus erythematosus 3 | 1,057

Tissue

Blood and immune system 94 | 16,909
Digestive Tract 94 | 17,369
Endocrine System 94 | 18,159
Female tissues 94 | 17,400
Male tissues 94 | 17,142
Nervous System 94 | 16,725
Skin and soft tissues 94 | 17,230
Liver and Pancreas 93 | 16,750
Urinary Tract 93 | 16,678
Respiratory system 92 | 16,393
Cardiovascular System 91 | 15,192

Target Family

Non-IDG 52 | 12,091
Enzyme 19 | 4,145
Kinase 15 | 634
TF/Epigenetic 3 | 38
Transcription Factor 3 | 1,400
Epigenetic 2 | 242
Ion Channel 1 | 344

GO Process

mitotic cell cycle 95 | 95
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin-specific chaperone D TBCD Tbio Non-IDG -1.71996 50.5 50
Kinesin-like protein KIF18B KIF18B Tbio Non-IDG -0.83463 5.23 17
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
Clathrin heavy chain 2 CLTCL1 Tbio Non-IDG -1.29555 21.3 39
ATP-dependent DNA helicase Q5 RECQL5 Tbio Enzyme -1.67373 56.2 148
Nucleotide triphosphate diphosphatase NUDT15 NUDT15 Tbio Enzyme -1.60299 37.9 77
Protein polybromo-1 PBRM1 Tchem TF/Epigenetic -1.92500 84.6 97
Kinesin-like protein KIF2C KIF2C Tbio Non-IDG -2.12404 136.3 256
Spindle and kinetochore-associated protein 2 SKA2 Tbio Non-IDG -1.23206 10.2 108
Protein SGT1 homolog SUGT1 Tbio Non-IDG -0.79781 9.93 183