Development Level

Tbio 18 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal clavicle morphology 1 | 6
abnormal coat- hair morphology 1 | 19
abnormal rib morphology 1 | 10
abnormal vitreous body morphol... 1 | 10
increased circulating bilirubi... 1 | 16
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 15 | 8,520
osteosarcoma 13 | 7,950
Carcinoma 12 | 11,493
lung cancer 10 | 4,740
medulloblastoma, large-cell 10 | 6,241
psoriasis 9 | 6,694
Optic Atrophy 6 | 242
glioblastoma 6 | 5,792
group 3 medulloblastoma 6 | 4,104
Kidney cancer 5 | 2,613
Multiple myeloma 5 | 1,332
tuberculosis 5 | 2,010
Blepharoptosis 4 | 231
Neuropathy 4 | 261
Schizophrenia 4 | 1,160
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
malignant mesothelioma 4 | 3,232
Alzheimer's disease 3 | 658
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Chronic progressive external ophthalmoplegia 3 | 26
Muscle hypotonia 3 | 571
Neurodegenerative disease 3 | 414
Polycystic ovary syndrome 3 | 360
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
ependymoma 3 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
3-methylglutaconic aciduria 2 | 29
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Acidosis, Lactic 2 | 97
Atrophy of cerebellum 2 | 103
Autosomal recessive predisposition 2 | 1,442
Babinski Reflex 2 | 100
Bell Palsy 2 | 58
Carcinoma, Hepatocellular 2 | 228
Cerebellar degeneration 2 | 103
Cognitive delay 2 | 608
Dull intelligence 2 | 645
Epilepsy 2 | 792
Facial Paresis 2 | 59
Facial muscle weakness of muscles innervated by CN VII 2 | 58
Failure to gain weight 2 | 365
Gait abnormality 2 | 135
Global developmental delay 2 | 608
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hyperreflexia 2 | 209
Impaired exercise tolerance 2 | 42
Infratentorial atrophy 2 | 103
Lactic acidemia 2 | 95
Liver carcinoma 2 | 240
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Mitochondrial complex I deficiency 2 | 46
Multiple Sclerosis 2 | 540
Muscle Spasticity 2 | 195
Myocardial Infarction 2 | 151
Myopathy 2 | 185
Nerve Degeneration 2 | 121
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Nonsyndromic deafness 2 | 142
Nystagmus 2 | 317
Pediatric failure to thrive 2 | 365
Phenotypic variability 2 | 150
Pick disease 2 | 1,894
Poor school performance 2 | 645
Prostatic Neoplasms 2 | 495
Reduced fetal movement 2 | 51
Reflex, Deep Tendon, Absent 2 | 92
Respiratory Failure 2 | 104
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Skeletal muscle atrophy 2 | 139
Strabismus 2 | 270
acute quadriplegic myopathy 2 | 1,158
colon cancer 2 | 1,478
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
hearing impairment 2 | 199
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
muscle degeneration 2 | 139
spina bifida 2 | 1,074

Tissue

Blood and immune system 21 | 16,909
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678

Target Family

Non-IDG 14 | 12,091
Enzyme 6 | 4,145
Kinase 1 | 634

GO Process

mitochondrion morphogenesis 21 | 21
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polymerase delta-interacting protein 2 POLDIP2 Tbio Enzyme 0.00000 154
Optic atrophy 3 protein OPA3 Tbio Non-IDG -1.67760 45.9 71
Myosin-14 MYH14 Tbio Non-IDG -1.41429 24.4 155
Dynamin-1-like protein DNM1L Tbio Non-IDG -2.65717 476.9 426
Iron-sulfur protein NUBPL NUBPL Tbio Non-IDG -1.75456 57.9 135
Dynamin-like 120 kDa protein, mitochondrial OPA1 Tbio Non-IDG -2.51554 307.1 210
Pantothenate kinase 2, mitochondrial PANK2 Tbio Kinase -2.24581 177.7 253
Fasciculation and elongation protein zeta-1 FEZ1 Tbio Non-IDG -1.36578 25.0 142
Mitochondrial fission 1 protein FIS1 Tbio Non-IDG -2.19572 143.4 224
Myotubularin MTM1 Tbio Enzyme -2.72507 527.3 235