Development Level

Tdark 58 | 6,588
Tbio 29 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 15 | 979
embryonic lethality prior to o... 7 | 239
embryonic lethality prior to t... 5 | 278
abnormal embryo size 4 | 220
embryonic growth retardation 4 | 106
abnormal bone structure 2 | 187
decreased circulating glucose ... 2 | 126
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal tail morphology 1 | 25
decreased circulating sodium l... 1 | 22
impaired pupillary reflex 1 | 26
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87

Disease

ovarian cancer 59 | 8,520
osteosarcoma 30 | 7,950
lung cancer 26 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
Carcinoma 17 | 11,493
non primary Sjogren syndrome sicca 16 | 891
psoriasis 16 | 6,694
Breast cancer 15 | 3,578
Multiple myeloma 15 | 1,332
group 3 medulloblastoma 14 | 4,104
medulloblastoma, large-cell 13 | 6,241
acute myeloid leukemia 12 | 783
glioblastoma 11 | 5,792
non-small cell lung cancer 11 | 2,890
atypical teratoid / rhabdoid tumor 9 | 5,112
Breast Neoplasms 8 | 445
Mammary Neoplasms 8 | 425
astrocytic glioma 8 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
adult high grade glioma 6 | 3,801
malignant mesothelioma 6 | 3,232
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
ependymoma 5 | 4,679
invasive ductal carcinoma 5 | 2,951
lung adenocarcinoma 5 | 2,716
pediatric high grade glioma 5 | 1,064
Brain glioma 4 | 7
Leigh disease 4 | 100
Pick disease 4 | 1,894
diabetes mellitus 4 | 1,728
Combined oxidative phosphorylation deficiency 3 | 14
Disease Progression 3 | 136
Stomach Neoplasms 3 | 300
Waldenstrons macroglobulinemia 3 | 765
cystic fibrosis 3 | 1,696
group 4 medulloblastoma 3 | 1,855
lung carcinoma 3 | 2,843
nasopharyngeal carcinoma 3 | 1,058
oligodendroglioma 3 | 2,850
subependymal giant cell astrocytoma 3 | 2,287
Adenocarcinoma of lung 2 | 142
Autosomal recessive predisposition 2 | 1,442
Disease Models, Animal 2 | 155
Elevated hepatic transaminases 2 | 81
Hepatic enzyme increased 2 | 81
Increased serum lactate 2 | 60
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Ophthalmoplegia 2 | 106
Optic Atrophy 2 | 242
Pseudoxanthoma elasticum 2 | 18
Retinitis pigmentosa 4 2 | 38
Subclinical abnormal liver function tests 2 | 81
Transaminases increased 2 | 81
active Crohn's disease 2 | 922
dermatomyositis 2 | 966
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
primitive neuroectodermal tumor 2 | 3,035
tuberculosis and treatment for 6 months 2 | 409
Acquired metabolic disease 1 | 336
Ankylosing spondylitis 1 | 140
Axonal neuropathy 1 | 27
Brachydactyly 1 | 156
Campylobacteriosis 1 | 11
Cardiovascular system disease 1 | 246
Congenital anomaly of face 1 | 56
Dilated ventricles (finding) 1 | 121
Distal arthrogryposis 1 | 42
Distortion of face 1 | 46
Dysmorphic facies 1 | 46
Funny looking face 1 | 46
Gaucher disease type 1 1 | 180
Hyper-beta-alaninemia 1 | 9
Hypertrophic Cardiomyopathy 1 | 117
Hypokinesia 1 | 19
Increased blood alanine 1 | 9
Increased serum alanine 1 | 9
Lateral medullary syndrome 1 | 4
Lethargy 1 | 77
Low Birth Weights 1 | 69
Mitochondrial Encephalomyopathies 1 | 7
Neonatal Hypotonia 1 | 64
Nonsyndromic deafness 1 | 142
Osteoarthritis 1 | 184
Osteoporosis 1 | 363
Prenatal onset 1 | 139
Small for gestational age (disorder) 1 | 69
Squamous cell carcinoma 1 | 129
Thrombophilia 1 | 38
Wilson-Turner syndrome 1 | 14
facial deformity 1 | 46
interstitial lung disease 1 | 298
posterior fossa group A ependymoma 1 | 468

Tissue

Blood and immune system 86 | 16,909
Cardiovascular System 86 | 15,192
Digestive Tract 86 | 17,369
Endocrine System 86 | 18,159
Female tissues 86 | 17,400
Liver and Pancreas 86 | 16,750
Male tissues 86 | 17,142
Nervous System 86 | 16,725
Respiratory system 86 | 16,393
Skin and soft tissues 86 | 17,230
Urinary Tract 86 | 16,678

Target Family

Non-IDG 82 | 12,091
Enzyme 6 | 4,145

GO Process

mitochondrial translational te... 88 | 88
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
39S ribosomal protein L22, mitochondrial MRPL22 Tdark Non-IDG 0.70 0.21 64
28S ribosomal protein S28, mitochondrial MRPS28 Tdark Non-IDG 0.00000 1.00 56
39S ribosomal protein L45, mitochondrial MRPL45 Tdark Non-IDG 0.51 0.23 0
39S ribosomal protein L49, mitochondrial MRPL49 Tbio Non-IDG -2.76367 555.1 76
39S ribosomal protein L11, mitochondrial MRPL11 Tdark Non-IDG -0.63555 3.41 198
39S ribosomal protein L20, mitochondrial MRPL20 Tdark Non-IDG 1.23 0.05 48
39S ribosomal protein L32, mitochondrial MRPL32 Tdark Non-IDG 0.18 0.93 52
39S ribosomal protein L9, mitochondrial MRPL9 Tdark Non-IDG 1.00 0.05 133
39S ribosomal protein L1, mitochondrial MRPL1 Tdark Non-IDG -0.74448 4.18 128
28S ribosomal protein S16, mitochondrial MRPS16 Tbio Non-IDG -0.33244 1.70 61