Development Level

Tdark 59 | 7,003
Tbio 26 | 10,625
Tchem 1 | 1,890

IMPC Phenotype

preweaning lethality, complete... 5 | 633
embryonic lethality prior to o... 4 | 148
embryonic lethality prior to t... 3 | 187
decreased circulating glucose ... 2 | 121
embryonic growth retardation 2 | 28
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
decreased CD11b-low dendritic ... 1 | 3
decreased grip strength 1 | 123
increased CD11b-high dendritic... 1 | 5
increased circulating creatini... 1 | 29
increased grip strength 1 | 83
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 58 | 8,491
osteosarcoma 31 | 7,933
lung cancer 25 | 4,473
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
non primary Sjogren syndrome sicca 15 | 840
psoriasis 15 | 6,685
Breast cancer 14 | 3,098
Multiple myeloma 13 | 1,327
medulloblastoma, large-cell 13 | 6,234
acute myeloid leukemia 12 | 785
glioblastoma 11 | 5,572
group 3 medulloblastoma 11 | 2,254
non-small cell lung cancer 11 | 2,798
Mammary Neoplasms 8 | 410
astrocytic glioma 8 | 2,241
atypical teratoid / rhabdoid tumor 8 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
malignant mesothelioma 6 | 3,163
pediatric high grade glioma 6 | 2,712
adult high grade glioma 5 | 2,148
breast carcinoma 5 | 1,614
colon cancer 5 | 1,475
invasive ductal carcinoma 5 | 2,950
lung adenocarcinoma 5 | 2,714
Pick disease 4 | 1,893
diabetes mellitus 4 | 1,663
Brain glioma 3 | 10
Disease Progression 3 | 125
Leigh disease 3 | 81
Ophthalmoplegia 3 | 18
Optic atrophy 3 | 43
Stomach Neoplasms 3 | 282
cystic fibrosis 3 | 1,670
ependymoma 3 | 2,514
lung carcinoma 3 | 2,844
nasopharyngeal carcinoma 3 | 1,056
oligodendroglioma 3 | 2,849
sonic hedgehog group medulloblastoma 3 | 1,482
subependymal giant cell astrocytoma 3 | 2,287
Combined oxidative phosphorylation deficiency 2 | 8
Down syndrome 2 | 548
Muscle Weakness 2 | 92
Pseudoxanthoma elasticum 2 | 19
Waldenstrons macroglobulinemia 2 | 764
active Crohn's disease 2 | 918
dermatomyositis 2 | 966
gastric cancer 2 | 436
hepatocellular carcinoma 2 | 550
hereditary spastic paraplegia 2 | 313
medulloblastoma 2 | 1,524
posterior fossa group A ependymoma 2 | 1,511
posterior fossa group B ependymoma 2 | 1,530
primitive neuroectodermal tumor 2 | 3,031
tuberculosis and treatment for 6 months 2 | 686
Acquired metabolic disease 1 | 267
Allergic rhinitis 1 | 92
Amyotrophic lateral sclerosis type 5 1 | 14
Ankylosing spondylitis 1 | 138
Axonal neuropathy 1 | 17
Campylobacteriosis 1 | 12
Cancer 1 | 2,346
Cardiovascular system disease 1 | 194
Charcot-Marie-Tooth disease 1 | 74
Coronary artery disease 1 | 240
DiGeorge syndrome 1 | 46
Diarrhea 1 | 155
Distal arthrogryposis 1 | 45
Dyslexia 1 | 36
Enamel caries 1 | 8
Epilepsy 1 | 346
Gastroenteritis 1 | 46
Gastroparesis 1 | 20
Gaucher disease type 1 1 | 171
Gilles de la Tourette syndrome 1 | 47
Melanoma 1 | 261
Migraine Disorders 1 | 26
Mitochondrial Encephalomyopathies 1 | 11
Neurodegenerative disease 1 | 383
Newcastle disease 1 | 13
Nicotine dependence 1 | 53
Nonsyndromic deafness 1 | 121
Osteoarthritis 1 | 96
Osteoporosis 1 | 259
Paraplegia 1 | 71
Specific language impairment 1 | 31
Squamous cell carcinoma 1 | 96
Thrombophilia 1 | 37
Velocardiofacial syndrome 1 | 45
active ulcerative colitis 1 | 477
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
aldosterone-producing adenoma 1 | 664
atypical teratoid/rhabdoid tumor 1 | 1,095
esophageal adenocarcinoma 1 | 737
inflammatory breast cancer 1 | 404
interstitial lung disease 1 | 292
progressive supranuclear palsy 1 | 674
tuberculosis 1 | 1,563

Tissue

Blood and immune system 86 | 17,994
Cardiovascular System 86 | 17,957
Digestive Tract 86 | 18,472
Endocrine System 86 | 18,511
Female tissues 86 | 18,646
Liver and Pancreas 86 | 18,135
Male tissues 86 | 17,968
Nervous System 86 | 18,560
Respiratory system 86 | 17,483
Urinary Tract 86 | 18,443
Skin and soft tissues 84 | 18,114

Target Family

Non-IDG 80 | 11,969
Enzyme 6 | 4,146

GO Process

mitochondrial translational te... 86 | 86
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
28S ribosomal protein S18a, mitochondrial MRPS18A Tdark Non-IDG 0.32 0.72 46
39S ribosomal protein L39, mitochondrial MRPL39 Tdark Non-IDG -0.45335 2.82 129
39S ribosomal protein L35, mitochondrial MRPL35 Tdark Non-IDG 0.00000 15
39S ribosomal protein L54, mitochondrial MRPL54 Tdark Non-IDG 0.00000 101
28S ribosomal protein S29, mitochondrial DAP3 Tbio Non-IDG -1.22289 22.6 243
39S ribosomal protein L40, mitochondrial MRPL40 Tbio Non-IDG -0.91127 7.33 90
28S ribosomal protein S14, mitochondrial MRPS14 Tdark Non-IDG 0.30 0.11 11
39S ribosomal protein L50, mitochondrial MRPL50 Tdark Non-IDG 0.90 0.13 77
39S ribosomal protein L28, mitochondrial MRPL28 Tbio Non-IDG -1.06383 10.7 186
39S ribosomal protein L33, mitochondrial MRPL33 Tdark Non-IDG 0.42 0.37 54