Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

improved glucose tolerance 2 | 79
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased prepulse inhibition 1 | 82
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased heart weight 1 | 62
preweaning lethality, complete... 1 | 979

Disease

medulloblastoma, large-cell 8 | 6,241
glioblastoma 7 | 5,792
ovarian cancer 7 | 8,520
Autosomal recessive predisposition 5 | 1,442
Breast cancer 5 | 3,578
Carcinoma 5 | 11,493
Chronic progressive external ophthalmoplegia 5 | 26
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
group 3 medulloblastoma 5 | 4,104
lung cancer 5 | 4,740
primitive neuroectodermal tumor 5 | 3,035
psoriasis 5 | 6,694
Blepharoptosis 4 | 231
Neuropathy 4 | 261
osteosarcoma 4 | 7,950
Acidosis, Lactic 3 | 97
Astrocytoma, Pilocytic 3 | 3,081
Cancer 3 | 2,499
Intellectual disability 3 | 1,016
Lactic acidemia 3 | 95
Multiple myeloma 3 | 1,332
Nystagmus 3 | 317
Progressive disorder 3 | 142
Sensorineural Hearing Loss (disorder) 3 | 284
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
oligodendroglioma 3 | 2,850
subependymal giant cell astrocytoma 3 | 2,287
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Cardiomyopathy 2 | 116
Cataract 2 | 297
Cerebellar Ataxia 2 | 304
Cognitive delay 2 | 608
Concave bridge of nose 2 | 195
Decreased activity of cytochrome C oxidase in muscle tissue 2 | 10
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Dull intelligence 2 | 645
Global developmental delay 2 | 608
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hypoplasia of corpus callosum 2 | 90
Lactic acidosis 2 | 51
Lens Opacities 2 | 231
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Mitochondrial Diseases 2 | 9
Multiple mitochondrial DNA (mtDNA) deletions 2 | 5
Muscle hypotonia 2 | 571
Myopathy 2 | 185
Ophthalmoplegia 2 | 106
Phenotypic variability 2 | 150
Pick disease 2 | 1,894
Poor school performance 2 | 645
Ptosis 2 | 48
Ragged-red fibers 2 | 21
Reflex, Deep Tendon, Absent 2 | 92
Rheumatoid arthritis 2 | 1,191
Short stature 2 | 531
Strabismus 2 | 270
Subsarcolemmal accumulations of abnormally shaped mitochondria 2 | 4
Ventricular Septal Defects 2 | 119
Vomiting 2 | 116
acute quadriplegic myopathy 2 | 1,158
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
malignant mesothelioma 2 | 3,232
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
ulcerative colitis 2 | 1,819
Abnormal auditory evoked potential 1 | 7
Abnormal color vision 1 | 31
Abnormal nasal morphology 1 | 16
Central cleft of nose 1 | 3
Color vision defect 1 | 33
Color vision defect, severe 1 | 31
Decreased pain sensation 1 | 17
Defective tooth enamel 1 | 31
Diabetic Cardiomyopathies 1 | 10
Dystrophic tooth enamel 1 | 31
Gastroparesis 1 | 22
Infantile onset spinocerebellar ataxia 1 | 7
Malignant tumor of colon 1 | 19
Midline defect of the nose 1 | 3
ODONTOID HYPOPLASIA 1 | 16
Overfolded helix 1 | 24
Polyneuropathy 1 | 64
Reduced visual acuity 1 | 63
Stomach cancer 1 | 30
Variation in muscle fiber size 1 | 16

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Enzyme 4 | 4,145
Non-IDG 3 | 12,091
Transporter 3 | 473
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

mitochondrial genome maintenan... 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 25 member 33 SLC25A33 Tbio Transporter -0.33020 1.54 45
ADP/ATP translocase 1 SLC25A4 Tbio Transporter -2.07841 114.8 103
Lon protease homolog, mitochondrial LONP1 Tbio Enzyme -2.24805 169.6 174
Dynamin-like 120 kDa protein, mitochondrial OPA1 Tbio Non-IDG -2.51554 307.1 210
39S ribosomal protein L17, mitochondrial MRPL17 Tdark Non-IDG 0.54 0.21 27
Mitochondrial genome maintenance exonuclease 1 MGME1 Tbio Enzyme -1.01082 8.97 50
Protein Mpv17 MPV17 Tbio Non-IDG -1.67807 47.6 134
Thymidine phosphorylase TYMP Tclin Enzyme -2.83170 677.8 514
ATP-dependent DNA helicase PIF1 PIF1 Tbio Enzyme -2.19803 156.5 67
Solute carrier family 25 member 36 SLC25A36 Tbio Transporter -1.16063 14.3 45