Development Level

Tbio 13 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal behavior 2 | 298
decreased vertical activity 2 | 208
hyperactivity 2 | 148
preweaning lethality, complete... 2 | 979
abnormal adrenal gland morphol... 1 | 1
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal thymus morphology 1 | 7
abnormal tooth morphology 1 | 24
aorta dilation 1 | 3
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hypoactivity 1 | 132
increased circulating bilirubi... 1 | 16
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
prolonged QT interval 1 | 38
shortened QT interval 1 | 4
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small thymus 1 | 16

Disease

medulloblastoma, large-cell 10 | 6,241
osteosarcoma 9 | 7,950
Carcinoma 8 | 11,493
ovarian cancer 8 | 8,520
glioblastoma 6 | 5,792
Neurodegenerative disease 5 | 414
Optic Atrophy 5 | 242
atypical teratoid / rhabdoid tumor 5 | 5,112
Autosomal recessive predisposition 4 | 1,442
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
ependymoma 4 | 4,679
malignant mesothelioma 4 | 3,232
medulloblastoma 4 | 720
psoriasis 4 | 6,694
Alzheimer's disease 3 | 658
Babinski Reflex 3 | 100
Infantile onset 3 | 238
Neuropathy 3 | 261
Pick disease 3 | 1,894
lung cancer 3 | 4,740
oligodendroglioma 3 | 2,850
ulcerative colitis 3 | 1,819
Abnormal color vision 2 | 31
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Acquired scoliosis 2 | 281
Astrocytoma, Pilocytic 2 | 3,081
Atrophy of cerebellum 2 | 103
Axonal degeneration/regeneration 2 | 7
Blepharoptosis 2 | 231
Blind spot located at fixation point 2 | 21
Breast Neoplasms 2 | 445
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Cerebellar Ataxia 2 | 304
Cerebellar degeneration 2 | 103
Ceroid lipofuscinosis, neuronal 1, infantile 2 | 10
Charcot-Marie-Tooth disease 2 | 62
Chronic progressive external ophthalmoplegia 2 | 26
Colonic Neoplasms 2 | 142
Color vision defect 2 | 33
Color vision defect, severe 2 | 31
Congenital pes cavus 2 | 88
Contracture 2 | 96
Contracture of joint 2 | 93
Curvature of spine 2 | 282
Decreased motor NCV 2 | 22
Decreased number of large and small myelinated fibers 2 | 20
Decreased tendon reflex 2 | 122
Decreased to absent deep tendon reflexes 2 | 42
Distal amyotrophy 2 | 51
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Distal sensory impairment 2 | 52
Dysmetric saccades 2 | 9
Esophageal Neoplasms 2 | 69
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Foot dorsiflexor weakness 2 | 27
Foot-drop 2 | 27
Gait abnormality 2 | 135
Gait, Drop Foot 2 | 24
Hammer Toe 2 | 23
Highly variable severity 2 | 157
Hoarse voice due to vocal cord paresis 2 | 3
Infratentorial atrophy 2 | 103
Mammary Neoplasms 2 | 425
Muscle Spasticity 2 | 195
Muscle weakness of limb 2 | 21
Nerve Degeneration 2 | 121
Obesity 2 | 678
Onion bulb formation 2 | 19
Partial Paralysis (Paresis) Vocal Cords 2 | 3
Peripheral Neuropathy 2 | 134
Polycystic ovary syndrome 2 | 360
Polyneuropathy 2 | 64
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
Reflex, Deep Tendon, Absent 2 | 92
Rheumatoid arthritis 2 | 1,191
Scotoma, Central 2 | 21
Slow progression 2 | 89
Variable expressivity 2 | 157
Vascular disease 2 | 319
Vocal cord paresis in severe cases 2 | 3
Waldenstrons macroglobulinemia 2 | 765
Weakness of vocal cord 2 | 3
aldosterone-producing adenoma 2 | 665
cutaneous lupus erythematosus 2 | 1,057
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
Slowed saccades 1 | 12

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Non-IDG 12 | 12,091
Enzyme 3 | 4,145

GO Process

mitochondrial fusion 15 | 15
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
MICOS complex subunit MIC19 CHCHD3 Tbio Non-IDG -1.16714 14.1 178
AFG3-like protein 2 AFG3L2 Tbio Enzyme -1.58716 39.9 164
Mitoguardin 1 MIGA1 Tbio Non-IDG -0.81790 6.81 22
Mitofusin-2 MFN2 Tbio Non-IDG -2.68784 484.6 447
Ubiquitin carboxyl-terminal hydrolase 30 USP30 Tbio Enzyme -1.23257 18.2 119
Ganglioside-induced differentiation-associated protein 1 GDAP1 Tbio Non-IDG -1.99050 105.9 77
Bcl-2 homologous antagonist/killer BAK1 Tbio Non-IDG -2.29199 175.9 554
Dynamin-like 120 kDa protein, mitochondrial OPA1 Tbio Non-IDG -2.51554 307.1 210
Bcl-2-related protein A1 BCL2A1 Tchem Non-IDG -3.07855 1146.2 307
Mitochondrial fission 1 protein FIS1 Tbio Non-IDG -2.19572 143.4 224