Development Level

Tbio 15 | 11,445
Tdark 5 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to t... 2 | 278
abnormal adrenal gland morphol... 1 | 1
abnormal coat- hair morphology 1 | 19
abnormal epididymis morphology 1 | 42
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal thymus morphology 1 | 7
abnormal vitreous body morphol... 1 | 10
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged heart 1 | 210
increased circulating bilirubi... 1 | 16
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
small thymus 1 | 16

Disease

Carcinoma 14 | 11,493
medulloblastoma, large-cell 9 | 6,241
ovarian cancer 9 | 8,520
glioblastoma 8 | 5,792
lung cancer 8 | 4,740
Optic Atrophy 6 | 242
atypical teratoid / rhabdoid tumor 6 | 5,112
group 3 medulloblastoma 6 | 4,104
malignant mesothelioma 6 | 3,232
psoriasis 6 | 6,694
Alzheimer's disease 5 | 658
Autosomal recessive predisposition 5 | 1,442
Breast cancer 5 | 3,578
Kidney cancer 5 | 2,613
adult high grade glioma 5 | 3,801
lung carcinoma 5 | 2,843
osteosarcoma 5 | 7,950
Astrocytoma, Pilocytic 4 | 3,081
Muscle hypotonia 4 | 571
Neurodegenerative disease 4 | 414
Pick disease 4 | 1,894
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
ependymoma 4 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
pancreatic cancer 4 | 2,398
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287
Absent reflex 3 | 92
Absent tendon reflex 3 | 92
Blepharoptosis 3 | 231
Dull intelligence 3 | 645
Hyperreflexia 3 | 209
Intellectual disability 3 | 1,016
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Motor delay 3 | 147
Neuropathy 3 | 261
No development of motor milestones 3 | 147
Poor school performance 3 | 645
Reflex, Deep Tendon, Absent 3 | 92
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
Acidosis, Lactic 2 | 97
Atopic dermatitis 2 | 952
Cancer 2 | 2,499
Chronic progressive external ophthalmoplegia 2 | 26
Congenital pes cavus 2 | 88
Contracture 2 | 96
Contracture of joint 2 | 93
Death in early childhood 2 | 82
Decreased number of large and small myelinated fibers 2 | 20
Decreased tendon reflex 2 | 122
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Dystonia 2 | 164
Dystonic disease 2 | 106
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Flexion contracture 2 | 93
Flexion contractures of joints 2 | 93
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Infantile onset 2 | 238
Influenza 2 | 142
Influenza, Human 2 | 51
Lactic acidemia 2 | 95
Multiple Sclerosis 2 | 540
Multiple myeloma 2 | 1,332
Muscle Spasticity 2 | 195
Myocardial Ischemia 2 | 169
Myopathy 2 | 185
Ophthalmoplegia 2 | 106
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Phenotypic variability 2 | 150
Proximal muscle weakness 2 | 47
Proximal neurogenic muscle weakness 2 | 47
Reduced fetal movement 2 | 51
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Strabismus 2 | 270
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 17 | 16,909
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678

Target Family

Non-IDG 18 | 12,091
Enzyme 3 | 4,145

GO Process

mitochondrial fission 21 | 21
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protoheme IX farnesyltransferase, mitochondrial COX10 Tbio Enzyme -1.60266 40.9 154
Putative GED domain-containing protein DNM1P46 DNM1P46 Tdark Non-IDG 0.00000 0
Mitochondrial fission regulator 1-like MTFR1L Tdark Non-IDG 0.00000 14
Interferon-induced GTP-binding protein Mx2 MX2 Tbio Non-IDG -2.62530 417.4 66
Mitochondrial fission regulator 1 MTFR1 Tbio Non-IDG -0.57007 3.69 75
Dynamin-1 DNM1 Tbio Non-IDG -2.67692 450.0 464
Mitochondrial ubiquitin ligase activator of NFKB 1 MUL1 Tbio Enzyme -2.41710 245.8 150
Dynamin-1-like protein DNM1L Tbio Non-IDG -2.65717 476.9 426
Ganglioside-induced differentiation-associated protein 1 GDAP1 Tbio Non-IDG -1.99050 105.9 77
Dynamin-like 120 kDa protein, mitochondrial OPA1 Tbio Non-IDG -2.51554 307.1 210