Development Level

Tbio 14 | 10,625
Tchem 2 | 1,890
Tdark 2 | 7,003
Tclin 1 | 602

IMPC Phenotype

preweaning lethality, complete... 4 | 633
pallor 3 | 13
abnormal embryo size 2 | 112
abnormal skin coloration 2 | 18
abnormal behavior 1 | 226
abnormal foot plate morphology 1 | 2
abnormal hindbrain development 1 | 24
abnormal limb bud morphology 1 | 15
abnormal liver size 1 | 4
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placenta development 1 | 1
abnormal placenta morphology 1 | 4
abnormal placenta size 1 | 10
abnormal skin appearance 1 | 8
decreased blood urea nitrogen ... 1 | 31
decreased startle reflex 1 | 48
embryonic growth retardation 1 | 28
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged heart atrium 1 | 2
hyperactivity 1 | 108
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
pale liver 1 | 5
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 8 | 8,491
Multiple myeloma 7 | 1,327
cytochrome-c oxidase deficiency disease 7 | 19
Cytochrome-c Oxidase Deficiency 5 | 15
Leigh disease 5 | 81
Mitochondrial complex IV deficiency 5 | 6
lung cancer 5 | 4,473
osteosarcoma 5 | 7,933
psoriasis 5 | 6,685
Breast cancer 4 | 3,098
Leigh syndrome 4 | 34
astrocytic glioma 4 | 2,241
atypical teratoid / rhabdoid tumor 4 | 4,369
glioblastoma 4 | 5,572
medulloblastoma, large-cell 4 | 6,234
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes 3 | 9
Obesity 3 | 616
Pick disease 3 | 1,893
Waldenstrons macroglobulinemia 3 | 764
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
ulcerative colitis 3 | 2,087
Chagas disease 2 | 34
Congenital myasthenic syndrome, acetazolamide-responsive 2 | 5
Fatal infantile encephalocardiomyopathy 2 | 3
Leber hereditary optic neuropathy 2 | 17
Lupus erythematosus 2 | 80
Malaria 2 | 140
Mitochondrial myopathy 2 | 24
Myasthenic Syndrome due to Mutation in SCN4A 2 | 5
Recurrent myoglobinuria mitochondrial 2 | 2
astrocytoma 2 | 1,493
ependymoma 2 | 2,514
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
oligodendroglioma 2 | 2,849
pediatric high grade glioma 2 | 2,712
Actinic keratosis 1 | 22
Amyotrophic lateral sclerosis type 5 1 | 14
Animal Mammary Neoplasms 1 | 135
Blood protein disease 1 | 10
Brain Ischemia 1 | 87
Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 2 1 | 1
Cardiomyopathies 1 | 90
Charcot-Marie-Tooth disease 1 | 74
Chloracne 1 | 32
Coenurosis 1 | 4
Colorectal Cancer 1 | 62
Cysticercosis 1 | 12
Dandy-Walker syndrome 1 | 10
Diabetes Mellitus, Experimental 1 | 106
Diabetes mellitus type 2 1 | 69
Diphyllobothriasis 1 | 6
Echinococcosis 1 | 28
Epilepsy, Temporal Lobe 1 | 23
Eye disease 1 | 55
Fascioliasis 1 | 18
Fatty Liver 1 | 48
Filariasis 1 | 21
Goldenhar syndrome 1 | 19
Heart disease 1 | 279
Hypertrophic Cardiomyopathy 1 | 56
Ischemia 1 | 27
Kidney disease 1 | 397
Kidney hypertrophy 1 | 4
Lactic acidosis 1 | 43
Leprosy 1 | 77
Lice infestation 1 | 16
MELAS syndrome 1 | 17
MICROPHTHALMIA, SYNDROMIC 7 1 | 3
Malignant glioma 1 | 23
Mammary Neoplasms, Experimental 1 | 149
Metabolic acidosis 1 | 49
Methylmalonic acidemia 1 | 39
Microphthalmia 1 | 79
Microphthalmia with linear skin defects syndrome 1 | 3
Muscle Weakness 1 | 92
Neuroblastoma 1 | 78
Neurodegenerative disease 1 | 383
Neuropathy 1 | 210
Newcastle disease 1 | 13
Nonsyndromic deafness 1 | 121
Opisthorchiasis 1 | 14
Paragonimiasis 1 | 9
Parkinson's disease 1 | 364
Protein C deficiency 1 | 19
Purpura fulminans 1 | 7
Renal tubular acidosis 1 | 14
Sclerocornea 1 | 16
Systemic scleroderma 1 | 66
Tethered spinal cord syndrome 1 | 12
Thrombocytopenia 1 | 105
Thrombophilia 1 | 37
Toxic encephalopathy 1 | 131
Treatment Refractory Type 2 Diabetes Mellitus 1 | 53
Troyer syndrome 1 | 3
Type 2 diabetes mellitus 1 | 192
Typhoid fever 1 | 22
Wegener's granulomatosis 1 | 14
hereditary spastic paraplegia 1 | 313
interstitial lung disease 1 | 292
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 19 | 17,994
Cardiovascular System 19 | 17,957
Digestive Tract 19 | 18,472
Endocrine System 19 | 18,511
Female tissues 19 | 18,646
Liver and Pancreas 19 | 18,135
Male tissues 19 | 17,968
Nervous System 19 | 18,560
Respiratory system 19 | 17,483
Skin and soft tissues 19 | 18,114
Urinary Tract 19 | 18,443

Target Family

Enzyme 18 | 4,146
Non-IDG 1 | 11,969

GO Process

mitochondrial electron transpo... 19 | 19
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protoheme IX farnesyltransferase, mitochondrial COX10 Tbio Enzyme -1.58383 36.7 127
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial COX4I2 Tbio Enzyme -1.62664 39.0 121
Cytochrome c oxidase subunit 3 MT-CO3 Tbio Enzyme -3.40472 2347.9 83
Cytochrome c oxidase subunit 8A, mitochondrial COX8A Tbio Enzyme -2.14257 127.1 50
Cytochrome c CYCS Tbio Non-IDG -3.74654 4771.4 630
Cytochrome c oxidase subunit 1 MT-CO1 Tchem Enzyme -3.64178 4179.7 118
Cytochrome c oxidase subunit 7C, mitochondrial COX7C Tdark Enzyme -1.02549 9.67 34
Cytochrome c oxidase subunit 7A-related protein, mitochondrial COX7A2L Tbio Enzyme -0.89948 8.18 90
Cytochrome c oxidase subunit 8C, mitochondrial COX8C Tdark Enzyme -0.21560 1.88 8
Cytochrome c oxidase subunit 2 MT-CO2 Tchem Enzyme -2.94466 857.2 116