Development Level

Tbio 19 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal sleep behavior 2 | 70
impaired righting response 2 | 26
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
abnormal coat appearance 1 | 31
abnormal sensory capabilities-... 1 | 8
absent vibrissae 1 | 12
decreased cardiac stroke volum... 1 | 6
decreased circulating glucose ... 1 | 126
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
enlarged testis 1 | 6
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
long tibia 1 | 25
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
small seminal vesicle 1 | 10

Disease

ovarian cancer 15 | 8,520
Carcinoma 13 | 11,493
osteosarcoma 9 | 7,950
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
psoriasis 7 | 6,694
glioblastoma 6 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
medulloblastoma, large-cell 6 | 6,241
Multiple myeloma 5 | 1,332
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Cerebellar Ataxia 4 | 304
astrocytic glioma 4 | 2,597
atypical teratoid / rhabdoid tumor 4 | 5,112
lung cancer 4 | 4,740
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Acquired scoliosis 3 | 281
Cancer 3 | 2,499
Curvature of spine 3 | 282
Dysarthria 3 | 192
Neurodegenerative disease 3 | 414
Nystagmus 3 | 317
Optic Atrophy 3 | 242
Paraplegia 3 | 74
group 3 medulloblastoma 3 | 4,104
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
ulcerative colitis 3 | 1,819
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Atrophy of cerebellum 2 | 103
Babinski Reflex 2 | 100
Blepharoptosis 2 | 231
Carcinoma, Hepatocellular 2 | 228
Cerebellar Dysmetria 2 | 56
Cerebellar degeneration 2 | 103
Chronic progressive external ophthalmoplegia 2 | 26
Cognitive delay 2 | 608
Deglutition Disorders 2 | 132
Epilepsy 2 | 792
Gait Ataxia 2 | 51
Global developmental delay 2 | 608
Hyperreflexia 2 | 209
Infantile onset 2 | 238
Infratentorial atrophy 2 | 103
Intellectual disability 2 | 1,016
Liver carcinoma 2 | 240
Mental and motor retardation 2 | 608
Muscle Spasticity 2 | 195
Muscle hypotonia 2 | 571
Pick disease 2 | 1,894
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Seizures 2 | 596
Waldenstrons macroglobulinemia 2 | 765
Wolf-Hirschhorn syndrome 2 | 32
acute myeloid leukemia 2 | 783
atypical teratoid/rhabdoid tumor 2 | 357
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
Acromesomelic dysplasia 1 | 10
Ataxia, Appendicular 1 | 25
Conjunctivitis 1 | 53
Dysdiadochokinesis 1 | 25
Dysmetric saccades 1 | 9
Familial cancer of breast 1 | 12
Gait, Unsteady 1 | 29
Gastroenteritis 1 | 41
Glomerulonephritis 1 | 46
Hyperkyphosis 1 | 111
Lower limb hyperreflexia 1 | 10
Myocardial Reperfusion Injury 1 | 37
Nystagmus, End-Position 1 | 12
Ophthalmoparesis 1 | 11
Paraparesis, Spastic 1 | 16
Psychoses, Substance-Induced 1 | 17
SPASTIC ATAXIA 5, AUTOSOMAL RECESSIVE 1 | 1
SPINOCEREBELLAR ATAXIA 28 1 | 1
Slowed saccades 1 | 12
Spastic Ataxia 1 | 18
Tonic - clonic seizures 1 | 44
Vesicoureteral reflux 1 | 32
spinocerebellar ataxia type 28 1 | 3

Tissue

Blood and immune system 23 | 16,909
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 12 | 12,091
Enzyme 6 | 4,145
Transporter 3 | 473
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

GO Process

mitochondrial calcium ion tran... 23 | 23
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium-binding mitochondrial carrier protein SCaMC-3 SLC25A23 Tbio Transporter -0.72246 7.27 53
Calcium uniporter protein, mitochondrial MCU Tbio Ion Channel -2.67075 458.1 25
Calcium uniporter regulatory subunit MCUb, mitochondrial MCUB Tdark Non-IDG -0.76467 3.88 57
AFG3-like protein 2 AFG3L2 Tbio Enzyme -1.58716 39.9 164
Calcium uptake protein 3, mitochondrial MICU3 Tdark Non-IDG -0.21085 1.14 50
ATP-dependent zinc metalloprotease YME1L1 YME1L1 Tbio Enzyme -2.42377 268.0 75
Mitochondrial sodium/calcium exchanger protein SLC8B1 Tbio Transporter -1.53269 33.9 58
Mitochondrial proton/calcium exchanger protein LETM1 Tbio Non-IDG -1.54149 41.5 189
Prohibitin-2 PHB2 Tbio Non-IDG -2.95347 911.7 370
Stomatin-like protein 2, mitochondrial STOML2 Tbio Non-IDG -0.84987 9.04 154