Development Level

Tbio 10 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

abnormal sleep behavior 2 | 70
impaired righting response 2 | 26
increased circulating sodium l... 2 | 71
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
abnormal coat appearance 1 | 31
abnormal eye size 1 | 7
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
enlarged spleen 1 | 41
enlarged testis 1 | 6
long tibia 1 | 25
prenatal lethality 1 | 28
preweaning lethality, complete... 1 | 979
small seminal vesicle 1 | 10

Disease

ovarian cancer 8 | 8,520
Carcinoma 7 | 11,493
osteosarcoma 6 | 7,950
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
psoriasis 4 | 6,694
Optic Atrophy 3 | 242
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung cancer 3 | 4,740
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
ulcerative colitis 3 | 1,819
Autosomal recessive predisposition 2 | 1,442
Blepharoptosis 2 | 231
Cerebellar Ataxia 2 | 304
Dystonia 2 | 164
Globe disease 2 | 67
Intellectual disability 2 | 1,016
Neurodegenerative disease 2 | 414
Seizures 2 | 596
Waldenstrons macroglobulinemia 2 | 765
Wolf-Hirschhorn syndrome 2 | 32
acute myeloid leukemia 2 | 783
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
group 4 medulloblastoma 2 | 1,855
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
primary pancreatic ductal adenocarcinoma 2 | 1,109
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
Asperger syndrome 1 | 37
Ataxia, Appendicular 1 | 25
Ataxia, Spinocerebellar 1 | 16
Auricular malformation 1 | 41
Bowed and upward slanting eyebrows 1 | 41
Calvarial defect 1 | 10
Cerebellar Dysmetria 1 | 56
Claw hand 1 | 26
Congenital anomaly of the kidney 1 | 12
Congenital diaphragmatic hernia 1 | 67
Convex nasal ridge 1 | 37
Cranial defect 1 | 10
Decreased muscle mass 1 | 28
Deglutition Disorders 1 | 132
Downturned corners of mouth 1 | 48
Dysdiadochokinesis 1 | 25
Dysmetric saccades 1 | 9
Early myoclonic encephalopathy 1 | 15
Fused vertebrae 1 | 25
Generalized hypotonia 1 | 37
Heart valve disease 1 | 39
Hyperkinesis 1 | 32
Hyperkyphosis 1 | 111
Hypodontia 1 | 81
Hypoplasia of thumb 1 | 26
Increased intramyocellular lipid droplets 1 | 13
Kyphosis deformity of spine 1 | 114
Learning Disorders 1 | 29
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Lower limb hyperreflexia 1 | 10
Macular degeneration 1 | 65
Metatarsus Varus 1 | 24
Motor Skills Disorders 1 | 8
Myoclonus 1 | 74
Neurodegeneration with brain iron accumulation 1 | 20
Neurodegeneration with brain iron accumulation 4 1 | 6
Nystagmus, End-Position 1 | 12
Ophthalmoparesis 1 | 11
Pain 1 | 103
Paraparesis, Spastic 1 | 16
Polydactyly preaxial type 1 1 | 9
Preauricular Fistulae, Congenital 1 | 27
Preauricular dimple 1 | 27
Preauricular sinus 1 | 27
Precocious Puberty 1 | 28
Retinitis pigmentosa Y-linked 1 | 9
Rib fusion 1 | 16
SPASTIC ATAXIA 5, AUTOSOMAL RECESSIVE 1 | 1
SPINOCEREBELLAR ATAXIA 28 1 | 1
Simple ear 1 | 41
Skull defect 1 | 10
Slowed saccades 1 | 12
Spastic Ataxia 1 | 18
Spinal fusion 1 | 25
Thick, flared eyebrows 1 | 41
Toeing-in 1 | 24
Tonic - clonic seizures 1 | 44
Vertebral body fusion 1 | 25
alcohol-related neurodevelopmental disorder 1 | 13
spinocerebellar ataxia type 28 1 | 3

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 10 | 12,091
Transporter 2 | 473
Enzyme 1 | 4,145

GO Process

mitochondrial calcium ion home... 13 | 13
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium uniporter regulatory subunit MCUb, mitochondrial MCUB Tdark Non-IDG -0.76467 3.88 57
AFG3-like protein 2 AFG3L2 Tbio Enzyme -1.58716 39.9 164
MICOS complex subunit MIC60 IMMT Tbio Non-IDG -2.81178 611.6 222
Mitochondrial sodium/calcium exchanger protein SLC8B1 Tbio Transporter -1.53269 33.9 58
Mitochondrial proton/calcium exchanger protein LETM1 Tbio Non-IDG -1.54149 41.5 189
Annexin A6 ANXA6 Tbio Non-IDG -2.44893 298.8 381
Protein C19orf12 C19orf12 Tbio Non-IDG -1.39201 25.6 6
m-AAA protease-interacting protein 1, mitochondrial MAIP1 Tdark Non-IDG 0.30 0.23 82
Calcium uptake protein 2, mitochondrial MICU2 Tbio Non-IDG -0.94183 7.15 63
Essential MCU regulator, mitochondrial SMDT1 Tbio Non-IDG -1.60735 39.4 11