Development Level

Tbio 18 | 11,178
Tclin 1 | 612

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
cleft palate 1 | 8
cyanosis 1 | 7
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 11 | 8,297
Carcinoma 10 | 11,192
Breast cancer 9 | 3,469
Cleft Palate 8 | 265
Craniofacial Abnormalities 8 | 141
invasive ductal carcinoma 8 | 2,867
lung cancer 8 | 4,607
medulloblastoma, large-cell 8 | 6,086
atypical teratoid / rhabdoid tumor 7 | 4,971
osteosarcoma 7 | 7,766
psoriasis 7 | 6,514
Autosomal recessive predisposition 6 | 1,407
Conductive hearing loss 6 | 122
Uranostaphyloschisis 6 | 162
ependymoma 6 | 4,559
oligodendroglioma 6 | 2,768
Hypoplastic mandible condyle 5 | 273
Intellectual disability 5 | 998
Mandibular hypoplasia 5 | 273
Micrognathism 5 | 273
adult high grade glioma 5 | 3,701
ductal carcinoma in situ 5 | 1,686
glioblastoma 5 | 5,635
lung carcinoma 5 | 2,755
malignant mesothelioma 5 | 3,135
non-small cell lung cancer 5 | 2,799
Astrocytoma, Pilocytic 4 | 3,006
Cancer 4 | 2,388
Cleft uvula 4 | 27
Decreased size of teeth 4 | 62
Decreased width of tooth 4 | 59
Dull intelligence 4 | 634
Low intelligence 4 | 634
Mental Retardation 4 | 634
Mental deficiency 4 | 634
Microdontia (disorder) 4 | 59
Narrow face 4 | 54
Obesity 4 | 655
Poor school performance 4 | 634
Retrognathia 4 | 53
Sensorineural Hearing Loss (disorder) 4 | 281
Short stature 4 | 514
Thin face 4 | 54
breast carcinoma 4 | 1,589
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,872
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,911
Absent auditory canals 3 | 23
Absent external auditory canals 3 | 23
Atresia of the external auditory canal 3 | 23
Atretic auditory canal 3 | 23
Bipolar Disorder 3 | 646
Broad hallux 3 | 29
Byzanthine arch palate 3 | 194
Cleft Lip 3 | 141
Cognitive delay 3 | 596
Congenital Heart Defects 3 | 57
Congenital deafness 3 | 180
Deafness 3 | 193
Delayed speech and language development 3 | 110
Downward slant of palpebral fissure 3 | 158
Epilepsy 3 | 775
Global developmental delay 3 | 596
Hearing Loss, Partial 3 | 180
Heart Defects, Congenital 3 | 36
Hydronephrosis 3 | 87
Language Delay 3 | 110
Long face 3 | 71
Low set ears 3 | 178
Mental and motor retardation 3 | 596
Nonsyndromic deafness 3 | 137
Orbital separation excessive 3 | 240
Osteoporosis 3 | 348
Pick disease 3 | 1,856
Preauricular Fistulae, Congenital 3 | 27
Preauricular dimple 3 | 27
Preauricular sinus 3 | 27
Preauricular skin tag 3 | 18
RENAL ADYSPLASIA 3 | 24
Renal dysplasia 3 | 26
Seizures 3 | 584
Short neck 3 | 139
Skin tag on the posterior cheek 3 | 18
Speech Delay 3 | 110
Speech impairment 3 | 110
Tooth agenesis 3 | 42
Townes-Brocks syndrome 3 | 12
astrocytic glioma 3 | 2,530
gastric carcinoma 3 | 781
group 3 medulloblastoma 3 | 4,002
group 4 medulloblastoma 3 | 1,806
hearing impairment 3 | 194
interstitial cystitis 3 | 2,237
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,902
non primary Sjogren syndrome sicca 3 | 861
sonic hedgehog group medulloblastoma 3 | 459
spina bifida 3 | 1,053
tuberculosis 3 | 1,963
ulcerative colitis 3 | 1,765
Prominent eyes 2 | 95
Protruding eyes 2 | 95

Tissue

Blood and immune system 19 | 16,909
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Respiratory system 18 | 16,393
Cardiovascular System 17 | 15,192
Nervous System 17 | 16,725

Target Family

Transcription Factor 10 | 1,400
Non-IDG 6 | 12,091
Kinase 2 | 634
Enzyme 1 | 4,145

GO Process

middle ear morphogenesis 19 | 19
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein Nkx-3.2 NKX3-2 Tbio Transcription Factor -1.63808 48.5 142
Protein odd-skipped-related 2 OSR2 Tbio Transcription Factor -1.44425 27.8 101
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.99519 95.5 207
60S ribosomal protein L38 RPL38 Tbio Non-IDG -1.40384 24.5 54
Alpha-N-acetylglucosaminidase NAGLU Tbio Enzyme -2.18649 159.9 64
Insulin-induced gene 2 protein INSIG2 Tbio Non-IDG -1.94599 88.7 78
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Teashirt homolog 1 TSHZ1 Tbio Transcription Factor -2.40972 252.7 133