Development Level

Tbio 18 | 10,625
Tclin 1 | 602
Tdark 1 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 2 | 633
abnormal embryo size 1 | 112
abnormal facial morphology 1 | 9
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
cleft palate 1 | 6
cyanosis 1 | 6
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
increased respiratory quotient 1 | 12

Disease

ovarian cancer 11 | 8,484
lung cancer 9 | 4,466
Craniofacial Abnormalities 8 | 147
invasive ductal carcinoma 8 | 2,950
medulloblastoma, large-cell 8 | 6,234
osteosarcoma 8 | 7,933
psoriasis 8 | 6,685
Breast cancer 7 | 3,094
Cleft palate 7 | 125
atypical teratoid / rhabdoid tumor 7 | 4,369
malignant mesothelioma 6 | 3,162
oligodendroglioma 6 | 2,849
adult high grade glioma 5 | 2,148
ductal carcinoma in situ 5 | 1,745
glioblastoma 5 | 5,572
lung carcinoma 5 | 2,844
non-small cell lung cancer 5 | 2,798
Cancer 4 | 2,346
Cleft Lip 4 | 91
Intellectual disability 4 | 573
breast carcinoma 4 | 1,614
ependymoma 4 | 2,514
group 4 medulloblastoma 4 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pilocytic astrocytoma 4 | 3,086
spina bifida 4 | 1,064
Branchiootorenal syndrome 3 | 9
Congenital Heart Defects 3 | 37
Obesity 3 | 616
Pick disease 3 | 1,893
Renal agenesis 3 | 25
Synostosis 3 | 18
Townes-Brocks syndrome 3 | 15
gastric carcinoma 3 | 832
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
non primary Sjogren syndrome sicca 3 | 840
sonic hedgehog group medulloblastoma 3 | 1,482
tuberculosis 3 | 1,557
ulcerative colitis 3 | 2,087
Atopic dermatitis 2 | 944
Atrial Fibrillation 2 | 110
Bamforth-Lazarus syndrome 2 | 4
Branchio-Oto-Renal Syndrome 2 | 4
Branchiootic syndrome 2 | 10
Carcinoma 2 | 2,147
Congenital Abnormality 2 | 11
Congenital heart disease 2 | 63
Esophageal atresia 2 | 25
Glaucoma 2 | 134
Goldenhar syndrome 2 | 19
Holoprosencephaly 2 | 52
Kidney Diseases 2 | 86
Kidney disease 2 | 396
Multiple myeloma 2 | 1,327
Osteoporosis 2 | 257
Polydactyly 2 | 93
Prostatic Neoplasms 2 | 471
Stomach Neoplasms 2 | 282
Tooth agenesis 2 | 36
Treacher Collins syndrome 2 | 29
X-linked cerebral adrenoleukodystrophy 2 | 115
acute quadriplegic myopathy 2 | 1,157
adrenocortical carcinoma 2 | 1,427
astrocytoma 2 | 1,493
diabetes mellitus 2 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
juvenile dermatomyositis 2 | 1,189
lung adenocarcinoma 2 | 2,713
nasopharyngeal carcinoma 2 | 1,056
non-inflammatory breast cancer 2 | 208
pancreatic cancer 2 | 2,300
posterior fossa group A ependymoma 2 | 1,511
primitive neuroectodermal tumor 2 | 3,031
subependymal giant cell astrocytoma 2 | 2,287
Achondroplasia 1 | 20
Acute Lung Injury 1 | 18
Ankylosis 1 | 25
CHARGE syndrome 1 | 23
Cardiac Arrhythmia 1 | 20
Cardiovascular Abnormalities 1 | 7
Congenital diaphragmatic hernia 1 | 43
Developmental absence of tooth 1 | 4
Dystonia Disorders 1 | 6
Embryo Loss 1 | 9
Facial paralysis 1 | 15
Hyperinsulinism 1 | 63
Hypodontia and nail dysgenesis 1 | 1
Hypoplastic enamel-onycholysis-hypohidrosis syndrome 1 | 1
Idiopathic hypogonadotropic hypogonadism 1 | 9
Klinefelter's syndrome 1 | 59
Lewy Body Disease 1 | 19
Nephrosis 1 | 18
OROFACIAL CLEFT 5 1 | 1
Parkinsonian Disorders 1 | 23
Sarcoma of soft tissue 1 | 11
Tooth Abnormalities 1 | 10
Tooth Agenesis, Familial 1 | 1
Tooth and nail syndrome 1 | 1

Tissue

Blood and immune system 20 | 17,995
Cardiovascular System 20 | 17,958
Digestive Tract 20 | 18,473
Endocrine System 20 | 18,512
Female tissues 20 | 18,647
Liver and Pancreas 20 | 18,136
Male tissues 20 | 17,969
Nervous System 20 | 18,561
Respiratory system 20 | 17,484
Skin and soft tissues 20 | 18,115
Urinary Tract 20 | 18,444

Target Family

Transcription Factor 11 | 1,400
Non-IDG 6 | 11,971
Kinase 2 | 634
Enzyme 1 | 4,146

GO Process

middle ear morphogenesis 20 | 20
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L38 RPL38 Tdark Non-IDG -1.39563 24.2 45
Insulin-induced gene 1 protein INSIG1 Tbio Non-IDG -2.25313 177.3 136
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.07424 1194.2 1600
T-box transcription factor TBX1 TBX1 Tbio Transcription Factor -1.94700 90.3 180
Homeobox protein Hox-A2 HOXA2 Tbio Transcription Factor -2.27536 194.5 72
Teashirt homolog 1 TSHZ1 Tbio Transcription Factor -2.37345 241.0 115
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.55832 374.1 270
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.51614 32.3 215
Insulin-induced gene 2 protein INSIG2 Tbio Non-IDG -1.92073 84.0 70
Alpha-N-acetylglucosaminidase NAGLU Tbio Enzyme -2.14685 152.0 61