Development Level

Tbio 23 | 11,445
Tchem 5 | 1,598
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 3 | 278
decreased body weight 2 | 161
hypoactivity 2 | 132
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal embryo size 1 | 220
abnormal facial morphology 1 | 17
abnormal sleep behavior 1 | 70
abnormal social-conspecific in... 1 | 3
anophthalmia 1 | 33
cleft palate 1 | 8
cyanosis 1 | 7
decreased circulating amylase ... 1 | 28
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hydroencephaly 1 | 14
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased lean body mass 1 | 172
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
prenatal lethality prior to he... 1 | 87
shortened ST segment 1 | 10
vertebral transformation 1 | 12

Disease

Carcinoma 18 | 11,493
psoriasis 15 | 6,694
ovarian cancer 13 | 8,520
osteosarcoma 12 | 7,950
lung cancer 10 | 4,740
group 3 medulloblastoma 9 | 4,104
medulloblastoma, large-cell 9 | 6,241
oligodendroglioma 9 | 2,850
Cancer 8 | 2,499
breast carcinoma 8 | 1,638
invasive ductal carcinoma 8 | 2,951
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Parkinson's disease 7 | 392
Schizophrenia 7 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Breast cancer 6 | 3,578
Cleft Palate 6 | 271
Intellectual disability 6 | 1,016
astrocytic glioma 6 | 2,597
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
glioblastoma 6 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
Autosomal recessive predisposition 5 | 1,442
Dull intelligence 5 | 645
Kidney cancer 5 | 2,613
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Short stature 5 | 531
acute quadriplegic myopathy 5 | 1,158
group 4 medulloblastoma 5 | 1,855
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Abnormally small eyeball 4 | 97
Amyotrophic lateral sclerosis 4 | 451
Bipolar Disorder 4 | 666
Cleft Lip 4 | 141
Craniofacial Abnormalities 4 | 151
Decreased size of eyeball 4 | 97
Epilepsy 4 | 792
Low Vision 4 | 174
Microphthalmos 4 | 100
Seizures 4 | 596
Strabismus 4 | 270
Uranostaphyloschisis 4 | 167
Visual Impairment 4 | 174
adrenocortical carcinoma 4 | 1,428
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
Agenesis of corpus callosum 3 | 83
Astrocytoma, Pilocytic 3 | 3,081
Breast Neoplasms 3 | 445
Decreased projection of maxilla 3 | 66
Deficiency of upper jaw bones 3 | 66
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Generalized osteopenia 3 | 99
Holoprosencephaly 3 | 56
Hydrocephalus 3 | 152
Hydronephrosis 3 | 89
Hypodontia 3 | 81
Hypoplasia of the maxilla 3 | 66
Hypoplastic mandible condyle 3 | 275
Hypospadias 3 | 53
Hypotrophic malar bone 3 | 129
Hypotrophic maxilla 3 | 66
Hypotrophic midface 3 | 105
Low-set, posteriorly rotated ears 3 | 110
Lung Neoplasms 3 | 232
Malar flattening 3 | 129
Mammary Neoplasms 3 | 425
Mandibular hypoplasia 3 | 275
Maxillary retrognathia 3 | 66
Micrognathism 3 | 275
Midface retrusion 3 | 105
Muscle hypotonia 3 | 571
Osteopenia 3 | 99
Osteoporosis 3 | 363
Respiratory distress 3 | 43
Retrusion of upper jaw bones 3 | 66
Small midface 3 | 105
Syndactyly 3 | 88
Syndactyly of fingers 3 | 48
Syndactyly of the toes 3 | 45
adult high grade glioma 3 | 3,801
agnathia-otocephaly complex 3 | 8
juvenile dermatomyositis 3 | 1,187
spina bifida 3 | 1,074

Tissue

Endocrine System 29 | 18,159
Female tissues 26 | 17,400
Nervous System 26 | 16,725
Skin and soft tissues 26 | 17,230
Digestive Tract 25 | 17,369
Male tissues 25 | 17,142
Blood and immune system 22 | 16,909
Liver and Pancreas 21 | 16,750
Respiratory system 21 | 16,393
Urinary Tract 21 | 16,678
Cardiovascular System 18 | 15,192

Target Family

Transcription Factor 15 | 1,400
Non-IDG 6 | 12,091
Enzyme 3 | 4,145
Epigenetic 3 | 242
Kinase 3 | 634

GO Process

midbrain development 30 | 30
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein B1 FOXB1 Tbio Transcription Factor -1.17019 15.7 110
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Transcription factor HES-3 HES3 Tbio Transcription Factor -1.61934 42.3 32
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 NDST1 Tbio Enzyme -1.91878 84.7 146
BarH-like 1 homeobox protein BARHL1 Tbio Transcription Factor -1.14434 12.3 108
Lysine-specific demethylase 2B KDM2B Tchem Epigenetic -1.56328 41.7 248
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.13063 1294.7 1785
Lysine-specific demethylase 7A KDM7A Tchem Epigenetic -1.02284 9.06 88
Growth/differentiation factor 7 GDF7 Tbio Non-IDG -1.56725 40.0 180
Paired mesoderm homeobox protein 2A PHOX2A Tbio Transcription Factor -1.75209 58.7 143