Development Level

Tbio 56 | 11,651
Tdark 10 | 6,593
Tchem 5 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 11 | 979
abnormal embryo size 3 | 220
preweaning lethality, incomple... 3 | 499
abnormal bone structure 2 | 187
abnormal seminal vesicle morph... 2 | 114
absent pinna reflex 2 | 23
cyanosis 2 | 7
decreased bone mineral content 2 | 151
decreased total body fat amoun... 2 | 207
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
increased fasted circulating g... 2 | 76
increased lean body mass 2 | 172
prenatal lethality prior to he... 2 | 87
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal cecum morphology 1 | 7
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal limb morphology 1 | 13
abnormal lung morphology 1 | 26
abnormal outer ear morphology 1 | 3
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged seminal vesicle 1 | 10
hemorrhage 1 | 23
hydrometra 1 | 53
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
long tibia 1 | 25
male infertility 1 | 123
microphthalmia 1 | 26
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Carcinoma 62 | 11,493
ovarian cancer 39 | 8,520
atypical teratoid / rhabdoid tumor 30 | 5,112
glioblastoma 30 | 5,792
medulloblastoma, large-cell 29 | 6,241
osteosarcoma 29 | 7,950
ependymoma 27 | 4,679
group 3 medulloblastoma 27 | 4,104
lung cancer 26 | 4,740
psoriasis 26 | 6,694
Breast cancer 25 | 3,578
adult high grade glioma 23 | 3,801
malignant mesothelioma 18 | 3,232
primitive neuroectodermal tumor 18 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
invasive ductal carcinoma 17 | 2,951
non-small cell lung cancer 17 | 2,890
adrenocortical carcinoma 16 | 1,428
oligodendroglioma 16 | 2,850
Astrocytoma, Pilocytic 15 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
lung adenocarcinoma 15 | 2,716
nasopharyngeal carcinoma 15 | 1,058
Kidney cancer 14 | 2,613
Endometriosis 13 | 540
ductal carcinoma in situ 13 | 1,745
lung carcinoma 13 | 2,843
Atopic dermatitis 12 | 952
breast carcinoma 11 | 1,638
colon cancer 11 | 1,478
Liver cancer 10 | 604
pituitary cancer 10 | 1,972
subependymal giant cell astrocytoma 10 | 2,287
astrocytic glioma 9 | 2,597
pancreatic cancer 9 | 2,398
Pick disease 8 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
Autosomal recessive predisposition 7 | 1,442
Cancer 7 | 2,499
chronic rhinosinusitis 7 | 512
Neuropathy 6 | 261
interstitial cystitis 6 | 2,312
Amyotrophic lateral sclerosis 5 | 451
Epilepsy 5 | 792
Intellectual disability 5 | 1,016
Neurodegenerative disease 5 | 414
Seizures 5 | 596
Small head 5 | 374
non-small cell lung carcinoma 5 | 317
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pediatric high grade glioma 5 | 1,064
ulcerative colitis 5 | 1,819
Cognitive delay 4 | 608
Endometrial cancer 4 | 311
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
Microcephaly 4 | 166
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
acute quadriplegic myopathy 4 | 1,158
astrocytoma 4 | 1,146
fibroadenoma 4 | 559
group 4 medulloblastoma 4 | 1,855
primary Sjogren syndrome 4 | 735
spina bifida 4 | 1,074
Alzheimer's disease 3 | 658
Cataract 8 multiple types 3 | 33
Ciliopathy 3 | 71
Concave bridge of nose 3 | 195
Congenital fibrosis of the extraocular muscles 3 | 13
Depressed nasal bridge 3 | 195
Depressed nasal root/bridge 3 | 195
Dull intelligence 3 | 645
Fetal Growth Retardation 3 | 189
Infant, Small for Gestational Age 3 | 176
Intrauterine retardation 3 | 176
Large intestine cancer 3 | 126
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Paraplegia 3 | 74
Parkinson's disease 3 | 392
Polydactyly 3 | 107
Poor school performance 3 | 645
Progressive muscular atrophy 3 | 7
Short stature 3 | 531
Sloping forehead 3 | 46
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
cystic fibrosis and chronic rhinosinusitis 3 | 214
diabetes mellitus 3 | 1,728
facioscapulohumeral dystrophy 3 | 288
posterior fossa group B ependymoma 3 | 416
progressive supranuclear palsy 3 | 676
Down syndrome 2 | 499

Tissue

Endocrine System 71 | 18,159
Digestive Tract 69 | 17,369
Female tissues 69 | 17,400
Male tissues 69 | 17,142
Nervous System 69 | 16,725
Respiratory system 69 | 16,393
Skin and soft tissues 69 | 17,230
Liver and Pancreas 68 | 16,750
Urinary Tract 68 | 16,678
Blood and immune system 67 | 16,909
Cardiovascular System 63 | 15,192

Target Family

Non-IDG 70 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634

GO Process

microtubule-based movement 72 | 72
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dynein heavy chain 6, axonemal DNAH6 Tbio Non-IDG -0.53057 4.17 18
Cytoplasmic dynein 1 light intermediate chain 1 DYNC1LI1 Tbio Non-IDG -1.67860 45.9 100
Endophilin-A1 SH3GL2 Tbio Non-IDG -1.79540 59.9 248
Kinesin-like protein KIF3A KIF3A Tbio Non-IDG -2.06068 113.6 153
Kinesin-like protein KIF22 KIF22 Tbio Non-IDG -1.69996 54.3 147
AP-2 complex subunit sigma AP2S1 Tbio Non-IDG -1.42073 25.5 108
AP-2 complex subunit beta AP2B1 Tbio Non-IDG -1.59767 34.8 212
Kinesin-like protein KIF6 KIF6 Tbio Non-IDG -1.53414 38.4 157
Dynein heavy chain 14, axonemal DNAH14 Tdark Non-IDG -0.25794 1.89 55
AP-2 complex subunit alpha-2 AP2A2 Tbio Non-IDG -0.65996 4.74 124