Development Level

Tbio 48 | 11,445
Tchem 15 | 1,598
Tdark 3 | 6,588

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
decreased body weight 2 | 161
increased circulating aspartat... 2 | 15
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal cranium morphology 1 | 36
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating sodium l... 1 | 22
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating iron lev... 1 | 30
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
microphthalmia 1 | 26
polycystic kidney 1 | 15

Disease

Carcinoma 53 | 11,493
ovarian cancer 43 | 8,520
osteosarcoma 34 | 7,950
ependymoma 33 | 4,679
glioblastoma 31 | 5,792
atypical teratoid / rhabdoid tumor 30 | 5,112
medulloblastoma, large-cell 28 | 6,241
psoriasis 28 | 6,694
group 3 medulloblastoma 26 | 4,104
adult high grade glioma 25 | 3,801
oligodendroglioma 25 | 2,850
lung cancer 24 | 4,740
Kidney cancer 23 | 2,613
astrocytic glioma 18 | 2,597
malignant mesothelioma 18 | 3,232
Breast cancer 17 | 3,578
Astrocytoma, Pilocytic 16 | 3,081
non-small cell lung cancer 16 | 2,890
Pick disease 15 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
invasive ductal carcinoma 14 | 2,951
subependymal giant cell astrocytoma 14 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
lung adenocarcinoma 13 | 2,716
primitive neuroectodermal tumor 13 | 3,035
Schizophrenia 12 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
lung carcinoma 12 | 2,843
Cancer 11 | 2,499
breast carcinoma 11 | 1,638
pituitary cancer 11 | 1,972
group 4 medulloblastoma 10 | 1,855
Intellectual disability 9 | 1,016
spina bifida 9 | 1,074
Autosomal recessive predisposition 8 | 1,442
Bipolar Disorder 8 | 666
Amyotrophic lateral sclerosis 7 | 451
Epilepsy 7 | 792
Multiple myeloma 7 | 1,332
Neurodegenerative disease 7 | 414
acute quadriplegic myopathy 7 | 1,158
colon cancer 7 | 1,478
ductal carcinoma in situ 7 | 1,745
Alzheimer's disease 6 | 658
Cognitive delay 6 | 608
Frontal bossing 6 | 157
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
adrenocortical carcinoma 6 | 1,428
astrocytoma 6 | 1,146
cutaneous lupus erythematosus 6 | 1,057
dermatomyositis 6 | 966
diabetes mellitus 6 | 1,728
interstitial cystitis 6 | 2,312
juvenile dermatomyositis 6 | 1,187
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
Anteverted nostril 5 | 191
Dull intelligence 5 | 645
Liver cancer 5 | 604
Low intelligence 5 | 645
Major Depressive Disorder 5 | 301
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Seizures 5 | 596
Short stature 5 | 531
Unipolar Depression 5 | 250
Waldenstrons macroglobulinemia 5 | 765
fibroadenoma 5 | 559
nasopharyngeal carcinoma 5 | 1,058
primary pancreatic ductal adenocarcinoma 5 | 1,109
3-M syndrome 4 | 15
Autistic Disorder 4 | 364
Defective tooth enamel 4 | 31
Deglutition Disorders 4 | 132
Delayed bone age 4 | 136
Depressive disorder 4 | 409
Down syndrome 4 | 499
Dystrophic tooth enamel 4 | 31
Enamel abnormalities 4 | 31
Fetal Growth Retardation 4 | 189
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Lissencephaly 4 | 69
Microcephaly 4 | 166
Obesity 4 | 678
Orbital separation excessive 4 | 244
Osteoporosis 4 | 363
Parkinson's disease 4 | 392
Rheumatoid arthritis 4 | 1,191
Slender, gracile long tubular bones 4 | 21
Toxic encephalopathy 4 | 141
chronic rhinosinusitis 4 | 512
cystic fibrosis 4 | 1,696
progressive supranuclear palsy 4 | 676
ulcerative colitis 4 | 1,819
acute myeloid leukemia 3 | 783
aldosterone-producing adenoma 3 | 665
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962

Tissue

Blood and immune system 66 | 16,909
Digestive Tract 66 | 17,369
Endocrine System 66 | 18,159
Female tissues 66 | 17,400
Liver and Pancreas 66 | 16,750
Male tissues 66 | 17,142
Nervous System 66 | 16,725
Skin and soft tissues 66 | 17,230
Urinary Tract 65 | 16,678
Respiratory system 64 | 16,393
Cardiovascular System 62 | 15,192

Target Family

Non-IDG 47 | 12,091
Kinase 11 | 634
Enzyme 8 | 4,145

GO Process

microtubule cytoskeleton organ... 66 | 66
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GAS2-like protein 3 GAS2L3 Tbio Non-IDG -0.65733 5.79 78
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.50271 33.3 93
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
MAP7 domain-containing protein 1 MAP7D1 Tdark Non-IDG 0.27 0.84 52
Serine/threonine-protein kinase MARK2 MARK2 Tchem Kinase -2.49873 272.3 322
E3 ubiquitin-protein ligase RNF19A RNF19A Tbio Enzyme -1.12489 15.5 142
Microtubule-associated protein 1A MAP1A Tbio Non-IDG -1.95729 72.8 67
MAP7 domain-containing protein 3 MAP7D3 Tbio Non-IDG -0.97069 8.06 11
CDK5 regulatory subunit-associated protein 2 CDK5RAP2 Tbio Non-IDG -1.70804 54.4 81