Development Level

Tbio 6 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal seminal vesicle morph... 1 | 114
enlarged heart 1 | 210
preweaning lethality, complete... 1 | 979

Disease

Breast cancer 7 | 3,578
Carcinoma 6 | 11,493
invasive ductal carcinoma 6 | 2,951
ovarian cancer 6 | 8,520
Cancer 4 | 2,499
malignant mesothelioma 4 | 3,232
non-small cell lung cancer 4 | 2,890
Kidney Failure 3 | 111
Kidney disease 3 | 430
Renal Insufficiency 3 | 90
Renal failure in adulthood 3 | 76
Sensorineural Hearing Loss (disorder) 3 | 284
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
lung cancer 3 | 4,740
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Blepharoptosis 2 | 231
Chronic kidney disease stage 5 2 | 31
Congenital absence of kidney 2 | 31
Denys-Drash syndrome 2 | 12
Dull intelligence 2 | 645
Epilepsy 2 | 792
Focal glomerulosclerosis 2 | 37
Glaucoma 2 | 239
Hepatomegaly 2 | 285
Highly variable severity 2 | 157
Hypertensive disease 2 | 292
Hypoplastic mandible condyle 2 | 275
Increase in blood pressure 2 | 119
Intellectual disability 2 | 1,016
Liver Cirrhosis, Experimental 2 | 769
Low Vision 2 | 174
Low intelligence 2 | 645
Lung Neoplasms 2 | 232
Mandibular hypoplasia 2 | 275
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Metanephric adenoma 2 | 9
Micrognathism 2 | 275
Nephrotic Syndrome 2 | 78
Polycystic Kidney - body part 2 | 18
Polycystic Kidney Diseases 2 | 20
Poor school performance 2 | 645
Primary physiologic amenorrhea 2 | 55
Progressive disorder 2 | 142
RENAL ADYSPLASIA 2 | 25
Renal dysplasia 2 | 28
Seizures 2 | 596
Skin hyperelastic 2 | 32
Small head 2 | 374
Variable expressivity 2 | 157
Vesico-Ureteral Reflux 2 | 33
Visual Impairment 2 | 174
Wilms Tumor 2 | 28
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
cystic fibrosis 2 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis 2 | 2,010
Aniridia 1 | 25
Aniridia 1 1 | 5
Autosomal dominant nonsyndromic deafness 10 1 | 4
Autosomal dominant nonsyndromic deafness 23 1 | 3
Bone Cysts 1 | 12
Branchioma 1 | 3
Contiguous gene syndrome 1 | 2
Deep overbite 1 | 4
Deletion 11p13 1 | 3
Displacement of the external urethral meatus 1 | 3
Dull foveal reflex 1 | 9
Foveal hypoplasia (finding) 1 | 9
Hyperplasia of supraorbital margins 1 | 19
Hyperplasia of supraorbital ridge 1 | 19
Hypertrophy of supraorbital margins 1 | 19
Hypertrophy of supraorbital ridge 1 | 19
Idiopathic hypereosinophilic syndrome 1 | 10
Incomplete partition of the cochlea type II 1 | 3
Lipoatrophy 1 | 19
Mondini malformation 1 | 3
Multiple, subcutaneous nodules 1 | 53
Myelodysplastic/ Myeloproliferative Diseases associated with Platelet-derived Growth Factor Receptor 1 | 9
Narrowing of ear canal 1 | 13
Pierson syndrome 1 | 13
Posterior lingual occlusion of mandibular teeth 1 | 4
Prominent supraorbital ridges 1 | 19
Raised TSH level 1 | 8
Stenosis of external auditory canal 1 | 13
Subcutaneous nodule 1 | 53
Vaginal malformation 1 | 7
WAGR syndrome 1 | 10
abnormal growth 1 | 26

Tissue

Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Urinary Tract 8 | 16,678
Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Liver and Pancreas 7 | 16,750
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Cardiovascular System 6 | 15,192

Target Family

Transcription Factor 5 | 1,400
Ion Channel 1 | 344
Kinase 1 | 634
Non-IDG 1 | 12,091

GO Process

metanephric mesenchyme develop... 8 | 8
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Wilms tumor protein WT1 Tbio Transcription Factor -3.48344 3138.9 571
Platelet-derived growth factor receptor beta PDGFRB Tclin Kinase -2.89315 712.3 1390
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
Homeobox protein SIX1 SIX1 Tbio Transcription Factor -2.64041 433.7 111
Polycystin-2 PKD2 Tchem Ion Channel -2.63806 461.3 231
Homeobox protein SIX4 SIX4 Tbio Transcription Factor -2.31722 197.8 141
Brain acid soluble protein 1 BASP1 Tbio Non-IDG -1.87756 78.6 123
Protein odd-skipped-related 1 OSR1 Tbio Transcription Factor -1.09901 15.0 343