Development Level

Tbio 8 | 11,651
Tchem 8 | 1,388
Tclin 1 | 612

IMPC Phenotype

abnormal bone structure 2 | 187
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal cornea morphology 1 | 31
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal limb morphology 1 | 13
abnormal skin condition 1 | 6
abnormal tail morphology 1 | 25
abnormal vibrissa morphology 1 | 25
cyanosis 1 | 7
decreased B cell number 1 | 5
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased granulocyte number 1 | 6
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
increased T cell number 1 | 6
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased leukocyte cell numbe... 1 | 47
increased thermal nociceptive ... 1 | 9
limb grasping 1 | 41
pale yolk sac 1 | 25
pallor 1 | 34
respiratory system phenotype 1 | 2
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

osteosarcoma 12 | 7,950
Carcinoma 11 | 11,493
glioblastoma 11 | 5,792
atypical teratoid / rhabdoid tumor 9 | 5,112
Alzheimer's disease 8 | 658
ependymoma 8 | 4,679
ovarian cancer 8 | 8,520
Astrocytoma, Pilocytic 7 | 3,081
Cancer 7 | 2,499
medulloblastoma, large-cell 6 | 6,241
Schizophrenia 5 | 1,160
adult high grade glioma 5 | 3,801
diabetes mellitus 5 | 1,728
primitive neuroectodermal tumor 5 | 3,035
ulcerative colitis 5 | 1,819
group 3 medulloblastoma 4 | 4,104
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
pediatric high grade glioma 4 | 1,064
Alzheimer Disease 3 | 83
Amyloidosis 3 | 67
Amyotrophic lateral sclerosis 3 | 451
Bipolar Disorder 3 | 666
Carcinoma, Hepatocellular 3 | 228
Cell Transformation, Neoplastic 3 | 97
Depressive disorder 3 | 409
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Hidradenitis suppurativa 3 | 13
Hidradenitis suppurativa, familial 3 | 3
Inflammatory bowel disease 3 | 151
Kidney Failure, Chronic 3 | 46
Kidney cancer 3 | 2,613
Liver Cirrhosis, Experimental 3 | 769
Liver carcinoma 3 | 240
Neoplastic Cell Transformation 3 | 89
Neurodegenerative disease 3 | 414
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
group 4 medulloblastoma 3 | 1,855
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
psoriasis 3 | 6,694
tuberculosis 3 | 2,010
Acne 2 | 52
Acquired scoliosis 2 | 281
Adenocarcinoma 2 | 122
Arthritis 2 | 290
Brain Ischemia 2 | 110
Cardiomyopathy 2 | 116
Cardiomyopathy, Dilated 2 | 83
Cerebral atrophy 2 | 178
Cerebrovascular disease 2 | 238
Cholestasis 2 | 155
Cholestasis, Extrahepatic 2 | 25
Chronic obstructive pulmonary disease 2 | 184
Colitis 2 | 54
Colonic Neoplasms 2 | 142
Congenital deafness 2 | 185
Congestive heart failure 2 | 113
Conjunctivitis 2 | 53
Corneal Ulcer 2 | 21
Coronary artery disease 2 | 268
Curvature of spine 2 | 282
Deafness 2 | 198
Decreased antibody level in blood 2 | 35
Dementia 2 | 175
Diabetes Mellitus, Experimental 2 | 108
Diabetic Nephropathies 2 | 37
Diabetic Nephropathy 2 | 34
Dilated cardiomyopathy 2 | 56
Epilepsy 2 | 792
Frontotemporal dementia 2 | 51
Hearing Loss, Partial 2 | 185
Heart failure 2 | 162
Highly variable severity 2 | 157
Hypertension 2 | 396
Hypogammaglobulinemia 2 | 35
Immunologic Deficiency Syndromes 2 | 113
Keratitis 2 | 62
Liver Cirrhosis 2 | 181
Mental Depression 2 | 333
Mood Disorders 2 | 184
Neoplasm Invasiveness 2 | 161
Nephrotic Syndrome 2 | 78
Nerve Degeneration 2 | 121
Neurodegenerative Disorders 2 | 79
Osteoporosis 2 | 363
Pneumonia 2 | 174
Syncope 2 | 22
Toxic encephalopathy 2 | 141
Variable expressivity 2 | 157
astrocytoma 2 | 1,146
hearing impairment 2 | 199
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
sarcoidosis 2 | 370
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 17 | 16,909
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678

Target Family

Enzyme 11 | 4,145
Non-IDG 4 | 12,091
Transcription Factor 2 | 1,400

GO Process

membrane protein intracellular... 17 | 17
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Gamma-secretase subunit APH-1B APH1B Tbio Enzyme -1.17035 13.6 56
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Membrane-bound transcription factor site-2 protease MBTPS2 Tbio Enzyme -1.94015 86.1 119
Disintegrin and metalloproteinase domain-containing protein 17 ADAM17 Tchem Enzyme -3.55216 3569.0 718
Membrane-bound transcription factor site-1 protease MBTPS1 Tchem Enzyme -1.49326 34.9 64
Nicastrin NCSTN Tbio Non-IDG -2.15220 133.2 357
Tumor necrosis factor receptor superfamily member 16 NGFR Tclin Non-IDG -3.06239 1162.1 881
Transcription factor p65 RELA Tchem Transcription Factor -3.00328 988.5 2215
Gamma-secretase subunit APH-1A APH1A Tbio Enzyme -1.87175 70.7 290