Development Level

Tchem 12 | 1,598
Tbio 8 | 11,445

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased vertical activity 2 | 208
preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal limb morphology 1 | 13
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased circulating glycerol... 1 | 16
edema 1 | 59
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
increased circulating alkaline... 1 | 122
increased grip strength 1 | 41
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2
small testis 1 | 58
unresponsive to tactile stimul... 1 | 8

Disease

osteosarcoma 17 | 7,950
ovarian cancer 15 | 8,520
Carcinoma 14 | 11,493
atypical teratoid / rhabdoid tumor 11 | 5,112
Alzheimer's disease 10 | 658
ependymoma 10 | 4,679
glioblastoma 10 | 5,792
medulloblastoma, large-cell 10 | 6,241
Astrocytoma, Pilocytic 8 | 3,081
Cancer 8 | 2,499
group 3 medulloblastoma 7 | 4,104
lung cancer 7 | 4,740
malignant mesothelioma 7 | 3,232
oligodendroglioma 7 | 2,850
pediatric high grade glioma 7 | 1,064
psoriasis 7 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
primitive neuroectodermal tumor 6 | 3,035
ulcerative colitis 6 | 1,819
Pick disease 5 | 1,894
Rheumatoid arthritis 5 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
progressive supranuclear palsy 5 | 676
subependymal giant cell astrocytoma 5 | 2,287
Alzheimer Disease 4 | 83
Amyloidosis 4 | 67
Dementia 4 | 175
Kidney cancer 4 | 2,613
Neurodegenerative disease 4 | 414
active Crohn's disease 4 | 922
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
astrocytoma 4 | 1,146
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
Acne 3 | 52
Autosomal recessive predisposition 3 | 1,442
Breast cancer 3 | 3,578
Cardiomyopathy 3 | 116
Crohn's disease 3 | 321
Down syndrome 3 | 499
Hidradenitis suppurativa 3 | 13
Hidradenitis suppurativa, familial 3 | 3
Schizophrenia 3 | 1,160
active ulcerative colitis 3 | 764
astrocytic glioma 3 | 2,597
cutaneous lupus erythematosus 3 | 1,057
juvenile dermatomyositis 3 | 1,187
non-small cell lung cancer 3 | 2,890
tuberculosis 3 | 2,010
Abdominal Pain 2 | 98
Amyotrophic lateral sclerosis 2 | 451
Ankylosing spondylitis 2 | 140
Arthralgia 2 | 90
Arthritis 2 | 290
Bipolar Disorder 2 | 666
Breast Neoplasms 2 | 445
Cardiomyopathy, Dilated 2 | 83
Common variable immunodeficiency 2 | 101
Congestive heart failure 2 | 113
Depressive disorder 2 | 409
Dilated cardiomyopathy 2 | 56
Disease Models, Animal 2 | 155
Disorder of eye 2 | 27
Epilepsy 2 | 792
Epistaxis 2 | 43
Fatigue 2 | 182
Fever 2 | 138
Frontotemporal dementia 2 | 51
Heart failure 2 | 162
Hematuria 2 | 36
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Mental Depression 2 | 333
Multiple Sclerosis 2 | 540
Multiple myeloma 2 | 1,332
Nausea and vomiting 2 | 97
Photodysphoria 2 | 121
Photophobia 2 | 121
Prostatic Neoplasms 2 | 495
Proteinuria 2 | 144
Syncope 2 | 22
Toxic encephalopathy 2 | 141
Vasculitis 2 | 80
aldosterone-producing adenoma 2 | 665
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
non diabetic and post-ischemic heart failure 2 | 200
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Blood and immune system 20 | 16,909
Digestive Tract 20 | 17,369
Female tissues 20 | 17,400
Nervous System 20 | 16,725
Skin and soft tissues 20 | 17,230
Cardiovascular System 19 | 15,192
Endocrine System 19 | 18,159
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Respiratory system 19 | 16,393
Urinary Tract 19 | 16,678

Target Family

Enzyme 15 | 4,145
Non-IDG 3 | 12,091
Ion Channel 1 | 344
Kinase 1 | 634

GO Process

membrane protein ectodomain pr... 20 | 20
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418
Disintegrin and metalloproteinase domain-containing protein 9 ADAM9 Tchem Enzyme -2.08807 122.3 258
Gamma-secretase subunit PEN-2 PSENEN Tchem Enzyme -2.84761 677.3 204
Disintegrin and metalloproteinase domain-containing protein 19 ADAM19 Tbio Enzyme -1.59365 43.0 184
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Presenilin-1 PSEN1 Tchem Enzyme -3.53128 3394.7 677
Disintegrin and metalloproteinase domain-containing protein 10 ADAM10 Tchem Enzyme -2.64652 422.4 384
Beta-secretase 1 BACE1 Tchem Enzyme -3.37358 2003.3 647
Signal peptide peptidase-like 2A SPPL2A Tbio Enzyme -1.34035 24.0 84
P2X purinoceptor 7 P2RX7 Tchem Ion Channel -2.96940 962.2 272