Development Level

Tbio 102 | 11,651
Tchem 18 | 1,388
Tclin 7 | 612
Tdark 3 | 6,593

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 8 | 499
decreased total body fat amoun... 6 | 207
abnormal behavior 4 | 298
decreased leukocyte cell numbe... 4 | 73
increased mean corpuscular vol... 4 | 92
decreased mean corpuscular hem... 3 | 50
decreased mean corpuscular vol... 3 | 79
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
enlarged lymph nodes 3 | 37
increased circulating HDL chol... 3 | 80
abnormal embryo size 2 | 220
abnormal eye anterior chamber ... 2 | 9
abnormal retina morphology 2 | 71
cardiovascular system phenotyp... 2 | 36
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased neutrophil cell numb... 2 | 42
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
edema 2 | 59
embryonic lethality prior to o... 2 | 239
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating potassiu... 2 | 29
increased erythrocyte cell num... 2 | 39
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 96
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
persistence of hyaloid vascula... 2 | 33
short tibia 2 | 97
thrombocytopenia 2 | 56
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal hair texture 1 | 4
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
absent pinna reflex 1 | 23
absent startle reflex 1 | 24
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating unsatura... 1 | 2
decreased fasted circulating g... 1 | 65
decreased heart rate variabili... 1 | 13
decreased large unstained cell... 1 | 11
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased monocyte cell number 1 | 8
decreased prepulse inhibition 1 | 82
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
hydrops fetalis 1 | 1
hyperactivity 1 | 148
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating LDL chol... 1 | 13
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased heart left ventricle... 1 | 4
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
microphthalmia 1 | 26
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
small superior vagus ganglion 1 | 74
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 93 | 11,493
ovarian cancer 85 | 8,520
osteosarcoma 75 | 7,950
psoriasis 70 | 6,694
glioblastoma 60 | 5,792
medulloblastoma, large-cell 60 | 6,241
atypical teratoid / rhabdoid tumor 51 | 5,112
lung cancer 46 | 4,740
ependymoma 43 | 4,679
Astrocytoma, Pilocytic 36 | 3,081
adult high grade glioma 36 | 3,801
Breast cancer 35 | 3,578
invasive ductal carcinoma 34 | 2,951
Cancer 33 | 2,499
astrocytic glioma 33 | 2,597
oligodendroglioma 33 | 2,850
pancreatic cancer 33 | 2,398
group 3 medulloblastoma 32 | 4,104
subependymal giant cell astrocytoma 32 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
lung carcinoma 28 | 2,843
primitive neuroectodermal tumor 28 | 3,035
Pick disease 27 | 1,894
intraductal papillary-mucinous neoplasm (IPMN) 27 | 3,291
malignant mesothelioma 27 | 3,232
Kidney cancer 26 | 2,613
Autosomal recessive predisposition 25 | 1,442
lung adenocarcinoma 25 | 2,716
non-small cell lung cancer 25 | 2,890
Multiple myeloma 23 | 1,332
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
interstitial cystitis 20 | 2,312
primary pancreatic ductal adenocarcinoma 20 | 1,109
acute quadriplegic myopathy 19 | 1,158
ductal carcinoma in situ 19 | 1,745
Rheumatoid arthritis 18 | 1,191
Schizophrenia 18 | 1,160
diabetes mellitus 17 | 1,728
juvenile dermatomyositis 17 | 1,187
dermatomyositis 16 | 966
pancreatic ductal adenocarcinoma liver metastasis 16 | 1,962
Alzheimer's disease 15 | 658
Waldenstrons macroglobulinemia 15 | 765
breast carcinoma 15 | 1,638
pituitary cancer 15 | 1,972
tuberculosis 15 | 2,010
Epilepsy 14 | 792
Bipolar Disorder 13 | 666
cystic fibrosis 13 | 1,696
group 4 medulloblastoma 13 | 1,855
progressive supranuclear palsy 13 | 676
Intellectual disability 12 | 1,016
Parkinson's disease 12 | 392
spina bifida 12 | 1,074
adrenocortical carcinoma 11 | 1,428
aldosterone-producing adenoma 11 | 665
astrocytoma 11 | 1,146
cutaneous lupus erythematosus 11 | 1,057
ulcerative colitis 11 | 1,819
Kidney disease 10 | 430
Seizures 10 | 596
esophageal adenocarcinoma 10 | 737
pediatric high grade glioma 10 | 1,064
Alcoholic Intoxication, Chronic 9 | 289
Cataract 8 multiple types 9 | 33
Down syndrome 9 | 499
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Neurodegenerative disease 9 | 414
Poor school performance 9 | 645
colon cancer 9 | 1,478
gastric carcinoma 9 | 807
Duchenne muscular dystrophy 8 | 601
Liver Cirrhosis, Experimental 8 | 769
Obesity 8 | 678
Oculocerebrorenal syndrome 8 | 29
pancreatic carcinoma 8 | 562
primary Sjogren syndrome 8 | 735
Acquired scoliosis 7 | 281
Atopic dermatitis 7 | 952
Cognitive delay 7 | 608
Curvature of spine 7 | 282
Failure to gain weight 7 | 365
Gaucher disease type 1 7 | 180
Global developmental delay 7 | 608
Major Depressive Disorder 7 | 301
Mammary Neoplasms, Experimental 7 | 154
Mental and motor retardation 7 | 608
Pediatric failure to thrive 7 | 365
Vascular disease 7 | 319
acute myeloid leukemia 7 | 783
non primary Sjogren syndrome sicca 7 | 891
Depressive disorder 6 | 409
Orbital separation excessive 6 | 244
Prostatic Neoplasms 6 | 495
Small nose 6 | 132
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
mucosa-associated lymphoid tissue lymphoma 6 | 484

Tissue

Skin and soft tissues 130 | 17,230
Endocrine System 129 | 18,159
Female tissues 129 | 17,400
Urinary Tract 129 | 16,678
Digestive Tract 128 | 17,369
Male tissues 128 | 17,142
Liver and Pancreas 127 | 16,750
Blood and immune system 126 | 16,909
Nervous System 126 | 16,725
Respiratory system 126 | 16,393
Cardiovascular System 123 | 15,192

Target Family

Non-IDG 104 | 12,091
Enzyme 13 | 4,145
Kinase 6 | 634
GPCR 4 | 408
Transporter 2 | 473
Ion Channel 1 | 344

GO Process

membrane organization 130 | 130
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Stonin-2 STON2 Tbio Non-IDG -1.43585 30.0 11
Epsin-1 EPN1 Tbio Non-IDG -1.52389 32.5 163
Vesicle-associated membrane protein 8 VAMP8 Tbio Non-IDG -1.79654 64.6 107
Sorting nexin-9 SNX9 Tbio Non-IDG -2.00279 102.8 241
Endophilin-A1 SH3GL2 Tbio Non-IDG -1.79540 59.9 248
14-3-3 protein beta/alpha YWHAB Tchem Non-IDG -2.06798 109.1 482
14-3-3 protein sigma SFN Tbio Non-IDG -2.56638 391.2 550
Leucyl-cystinyl aminopeptidase LNPEP Tchem Enzyme -2.57244 394.0 103
Vasopressin-neurophysin 2-copeptin AVP Tbio Non-IDG -3.92570 8381.2 203
Pro-epidermal growth factor EGF Tbio Non-IDG -3.75933 4903.2 978