Development Level

Tbio 11 | 11,445
Tchem 8 | 1,598
Tclin 5 | 613

Collection

Ion Channel: IDG Consortium (T... 4 | 99

IMPC Phenotype

increased circulating alanine ... 2 | 13
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
cataract 1 | 92
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating glycerol... 1 | 16
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hyperactivity 1 | 148
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 16 | 11,493
glioblastoma 15 | 5,792
psoriasis 14 | 6,694
Astrocytoma, Pilocytic 13 | 3,081
medulloblastoma, large-cell 13 | 6,241
atypical teratoid / rhabdoid tumor 12 | 5,112
adult high grade glioma 11 | 3,801
ependymoma 11 | 4,679
ovarian cancer 11 | 8,520
lung carcinoma 10 | 2,843
Cancer 9 | 2,499
Epilepsy 9 | 792
Schizophrenia 9 | 1,160
oligodendroglioma 9 | 2,850
primitive neuroectodermal tumor 9 | 3,035
group 3 medulloblastoma 8 | 4,104
Bipolar Disorder 7 | 666
lung cancer 7 | 4,740
osteosarcoma 7 | 7,950
Breast cancer 6 | 3,578
astrocytic glioma 6 | 2,597
invasive ductal carcinoma 6 | 2,951
malignant mesothelioma 6 | 3,232
ulcerative colitis 6 | 1,819
Alzheimer's disease 5 | 658
Depressive disorder 5 | 409
Heart disease 5 | 306
Intellectual disability 5 | 1,016
Pick disease 5 | 1,894
Sudden infant death syndrome 5 | 32
diabetes mellitus 5 | 1,728
lung adenocarcinoma 5 | 2,716
non-small cell lung cancer 5 | 2,890
subependymal giant cell astrocytoma 5 | 2,287
Arthritis 4 | 290
Atrial Fibrillation 4 | 124
Autosomal recessive predisposition 4 | 1,442
Cerebellar Ataxia 4 | 304
Hypertension 4 | 396
Hypertensive disease 4 | 292
Inflammation 4 | 120
Kidney cancer 4 | 2,613
Liver Cirrhosis, Experimental 4 | 769
Liver cancer 4 | 604
Parkinson's disease 4 | 392
Rheumatoid arthritis 4 | 1,191
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pituitary cancer 4 | 1,972
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 3 | 21
Amyotrophic lateral sclerosis 3 | 451
Asthma 3 | 385
Atherosclerosis 3 | 291
Brugada Syndrome (disorder) 3 | 15
Brugada syndrome 3 | 29
Carcinoma, Hepatocellular 3 | 228
Cardiac Arrhythmia 3 | 103
Cardiomegaly 3 | 116
Dystonia 3 | 164
Familial atrial fibrillation 3 | 23
Hyperglycemia 3 | 137
Hyperinsulinism 3 | 133
Kidney disease 3 | 430
Liver carcinoma 3 | 240
Lung disease 3 | 142
Major Depressive Disorder 3 | 301
Mental Depression 3 | 333
Mood Disorders 3 | 184
Neurodegenerative disease 3 | 414
Niacin deficiency 3 | 5
Nicotine Withdrawal Symptoms 3 | 5
Nicotine dependence 3 | 54
Obesity 3 | 678
Pellagra 3 | 26
Pulmonary Fibrosis 3 | 106
Reperfusion Injury 3 | 86
Seizures 3 | 596
Smoking cessation assistance 3 | 8
Stomach Neoplasms 3 | 300
Substance Withdrawal Syndrome 3 | 55
Sudden Infant Death 3 | 4
Toxic encephalopathy 3 | 141
Vascular disease 3 | 319
acute myeloid leukemia 3 | 783
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
fibroadenoma 3 | 559
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
spina bifida 3 | 1,074
Abnormal behavior 2 | 52
Cerebrovascular accident 2 | 63
Movement Disorders 2 | 55
Neuropathy 2 | 261
Progressive disorder 2 | 142
Status Epilepticus 2 | 98
medulloblastoma 2 | 720

Tissue

Endocrine System 24 | 18,159
Nervous System 24 | 16,725
Digestive Tract 23 | 17,369
Female tissues 23 | 17,400
Blood and immune system 22 | 16,909
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678
Respiratory system 19 | 16,393
Cardiovascular System 18 | 15,192

Target Family

Ion Channel 16 | 344
Non-IDG 3 | 12,091
Enzyme 1 | 4,145
Epigenetic 1 | 242
GPCR 1 | 408
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

membrane depolarization 24 | 24
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuronal acetylcholine receptor subunit beta-2 CHRNB2 Tclin Ion Channel -1.62448 37.6 174
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.24422 170.7 75
Bestrophin-2 BEST2 Tbio Ion Channel -1.23844 17.2 109
Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A Tchem Ion Channel -3.06226 1140.1 64
Histone-lysine N-methyltransferase 2A KMT2A Tchem Epigenetic -2.88228 736.0 334
P2X purinoceptor 7 P2RX7 Tchem Ion Channel -2.96940 962.2 272
Protein/nucleic acid deglycase DJ-1 PARK7 Tbio Enzyme -2.89261 835.5 625
Sodium channel subunit beta-3 SCN3B Tbio Ion Channel -0.97654 10.5 71
Voltage-dependent calcium channel gamma-2 subunit CACNG2 Tbio Ion Channel -1.92203 89.6 173
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607