Development Level

Tbio 20 | 11,445
Tchem 1 | 1,598

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased anti-nuclear antigen... 1 | 19
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
thrombocytopenia 1 | 56

Disease

ovarian cancer 13 | 8,520
osteosarcoma 12 | 7,950
psoriasis 11 | 6,694
medulloblastoma, large-cell 9 | 6,241
atypical teratoid / rhabdoid tumor 8 | 5,112
glioblastoma 8 | 5,792
Autosomal recessive predisposition 7 | 1,442
Carcinoma 7 | 11,493
Intellectual disability 7 | 1,016
Nystagmus 7 | 317
Obesity 7 | 678
malignant mesothelioma 7 | 3,232
Bardet-Biedl syndrome 6 | 51
Bardet-Biedl syndrome 1 6 | 22
Breast cancer 6 | 3,578
Pick disease 6 | 1,894
ependymoma 6 | 4,679
oligodendroglioma 6 | 2,850
Astrocytoma, Pilocytic 5 | 3,081
Ciliopathy 5 | 71
Cone dystrophy 5 | 71
Dull intelligence 5 | 645
Hermansky-Pudlak syndrome 5 | 42
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Polydactyly 5 | 107
Poor school performance 5 | 645
Retinitis Pigmentosa 5 | 226
adult high grade glioma 5 | 3,801
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
invasive ductal carcinoma 5 | 2,951
pancreatic cancer 5 | 2,398
Cognitive delay 4 | 608
Congenital hypoplasia of ovary 4 | 30
Congenital hypoplasia of penis 4 | 176
Electroretinogram abnormal 4 | 95
Fundus dystrophy 4 | 83
Global developmental delay 4 | 608
Griscelli syndrome 4 | 24
Hypertensive disease 4 | 292
Hypogonadism 4 | 173
Hypoplastic ovary 4 | 30
Increase in blood pressure 4 | 119
Mental and motor retardation 4 | 608
Multicystic Dysplastic Kidney 4 | 52
Oculocutaneous albinism 4 | 29
Platelet storage pool deficiency 4 | 21
Short stature 4 | 531
Small genitalia 4 | 13
Ulnar polydactyly of fingers 4 | 47
astrocytic glioma 4 | 2,597
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
pituitary cancer 4 | 1,972
Cerebellar Ataxia 3 | 304
Chediak-Higashi syndrome 3 | 26
Choroideremia 3 | 16
Hemophagocytic lymphohistiocytosis 3 | 30
Hypopigmentation disorder 3 | 25
Retinal Degeneration 3 | 106
Strabismus 3 | 270
acute quadriplegic myopathy 3 | 1,158
ductal carcinoma in situ 3 | 1,745
gastric cancer 3 | 459
gastric carcinoma 3 | 807
group 4 medulloblastoma 3 | 1,855
lung carcinoma 3 | 2,843
medulloblastoma 3 | 720
non-small cell lung cancer 3 | 2,890
posterior fossa group B ependymoma 3 | 416
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Asthma 2 | 385
Delayed speech and language development 2 | 112
Epilepsy 2 | 792
Infantile onset 2 | 238
Kidney cancer 2 | 2,613
Language Delay 2 | 112
Multiple myeloma 2 | 1,332
Muscle Spasticity 2 | 195
Neurodegenerative disease 2 | 414
Schizophrenia 2 | 1,160
Seizures 2 | 596
Speech Delay 2 | 112
Speech Disorders 2 | 58
Speech impairment 2 | 112
aldosterone-producing adenoma 2 | 665
cutaneous lupus erythematosus 2 | 1,057
hepatocellular carcinoma 2 | 547
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678
Cardiovascular System 19 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 7 | 4,145
GPCR 1 | 408

GO Process

melanosome transport 21 | 21
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bardet-Biedl syndrome 4 protein BBS4 Tbio Non-IDG -1.53435 31.5 200
Biogenesis of lysosome-related organelles complex 1 subunit 3 BLOC1S3 Tbio Non-IDG -0.81676 0.00000 66
Bardet-Biedl syndrome 2 protein BBS2 Tbio Non-IDG -2.84516 693.9 69
Biogenesis of lysosome-related organelles complex 1 subunit 5 BLOC1S5 Tbio Non-IDG -1.38771 23.5 97
Agouti-signaling protein ASIP Tbio Non-IDG -1.78281 57.2 34
McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin MKKS Tbio Non-IDG -2.12522 127.5 112
Ras-related protein Rab-11A RAB11A Tbio Enzyme -2.65458 432.1 352
Ras-related protein Rab-27A RAB27A Tchem Enzyme -2.30319 204.9 308
Bardet-Biedl syndrome 7 protein BBS7 Tbio Non-IDG -1.05503 10.4 159
Unconventional myosin-Va MYO5A Tbio Non-IDG -1.77097 54.9 83