Development Level

Tbio 11 | 11,445
Tclin 4 | 613
Tchem 3 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to t... 2 | 278
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal head morphology 1 | 10
abnormal male genitalia morpho... 1 | 3
abnormal startle reflex 1 | 15
decreased body weight 1 | 161
decreased brain size 1 | 4
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
fusion of vertebral arches 1 | 7
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
limb grasping 1 | 41
mammalian phenotype 1 | 17
polysyndactyly 1 | 2
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small thymus 1 | 16
vertebral transformation 1 | 12

Disease

Carcinoma 13 | 11,493
lung cancer 11 | 4,740
psoriasis 11 | 6,694
lung carcinoma 9 | 2,843
Cancer 8 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
malignant mesothelioma 7 | 3,232
osteosarcoma 7 | 7,950
ovarian cancer 7 | 8,520
Autosomal recessive predisposition 6 | 1,442
Breast cancer 6 | 3,578
Hypospadias 6 | 53
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
medulloblastoma, large-cell 6 | 6,241
pancreatic cancer 6 | 2,398
Cryptorchidism 5 | 296
Kidney cancer 5 | 2,613
atypical teratoid / rhabdoid tumor 5 | 5,112
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
ductal carcinoma in situ 5 | 1,745
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
non-small cell lung cancer 5 | 2,890
Cleft Palate 4 | 271
Congenital hypoplasia of penis 4 | 176
Dull intelligence 4 | 645
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
Prostate cancer 4 | 175
Prostatic Neoplasms 4 | 495
adrenocortical carcinoma 4 | 1,428
cystic fibrosis 4 | 1,696
spina bifida 4 | 1,074
Abnormality of metabolism/homeostasis 3 | 134
Alzheimer's disease 3 | 658
Bilateral fifth finger clinodactyly 3 | 110
Breast Neoplasms 3 | 445
Choanal Atresia 3 | 42
Cleft Lip 3 | 141
Cognitive delay 3 | 608
Craniofacial Abnormalities 3 | 151
Curvature of little finger 3 | 110
Global developmental delay 3 | 608
Hydronephrosis 3 | 89
Hypogonadism 3 | 173
Hypogonadism, Isolated Hypogonadotropic 3 | 71
Hypogonadotropic hypogonadism 3 | 89
Liver cancer 3 | 604
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Mental and motor retardation 3 | 608
Nausea and vomiting 3 | 97
Osteoarthritis 3 | 184
Parkinson's disease 3 | 392
Polydactyly 3 | 107
Pseudohermaphroditism 3 | 16
Schizophrenia 3 | 1,160
Short stature 3 | 531
Skin cancer 3 | 469
Small head 3 | 374
Somatic mutation 3 | 61
Stomach Neoplasms 3 | 300
Strabismus 3 | 270
Ventricular Septal Defects 3 | 119
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
sonic hedgehog group medulloblastoma 3 | 467
tuberculosis 3 | 2,010
Abnormality of the voice 2 | 46
Alcoholic Intoxication, Chronic 2 | 289
Anemia 2 | 365
Carcinoma, Hepatocellular 2 | 228
Colonic Neoplasms 2 | 142
Flexion contracture of proximal interphalangeal joint 2 | 75
Hernia, Inguinal 2 | 89
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Infertility 2 | 188
Isolated cases 2 | 72
Liver Cirrhosis, Experimental 2 | 769
Liver carcinoma 2 | 240
Lung Neoplasms 2 | 232
Mesothelioma, Malignant 2 | 105
Penile hypospadias 2 | 106
Phenotypic variability 2 | 150
Premature Birth 2 | 77
Premature birth of newborn 2 | 67

Tissue

Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Urinary Tract 18 | 16,678
Skin and soft tissues 17 | 17,230
Digestive Tract 16 | 17,369
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 15 | 16,725
Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Respiratory system 14 | 16,393

Target Family

Non-IDG 8 | 12,091
Enzyme 4 | 4,145
Transcription Factor 3 | 1,400
GPCR 2 | 408
Kinase 2 | 634

GO Process

male genitalia development 19 | 19
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-box transcription factor TBX3 TBX3 Tbio Transcription Factor -2.42253 255.6 328
Ankyrin repeat and SOCS box protein 1 ASB1 Tdark Non-IDG -1.02325 9.75 26
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317
Testis-expressed protein 15 TEX15 Tbio Non-IDG -1.05372 9.87 11
Homeobox protein Hox-D13 HOXD13 Tbio Transcription Factor -2.30244 199.6 197
Lutropin-choriogonadotropic hormone receptor LHCGR Tclin GPCR -2.58909 376.4 243
Wilms tumor protein WT1 Tbio Transcription Factor -3.48344 3138.9 571
Testosterone 17-beta-dehydrogenase 3 HSD17B3 Tchem Enzyme -2.03781 102.2 140
Leucine-rich repeat-containing G-protein coupled receptor 4 LGR4 Tbio GPCR -1.75604 72.2 230
Tyrosine-protein kinase transmembrane receptor ROR2 ROR2 Tbio Kinase -1.88065 80.4 419