Development Level

Tbio 8 | 11,445
Tchem 7 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal heart left ventricle ... 1 | 16
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
decreased bone mineral content 1 | 151
decreased circulating aspartat... 1 | 34
decreased circulating serum al... 1 | 82
decreased heart weight 1 | 27
decreased spleen weight 1 | 10
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged kidney 1 | 14
increased circulating alkaline... 1 | 122
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134

Disease

Carcinoma 13 | 11,493
Cancer 12 | 2,499
lung cancer 9 | 4,740
osteosarcoma 9 | 7,950
ovarian cancer 9 | 8,520
Breast Neoplasms 8 | 445
Mammary Neoplasms 8 | 425
psoriasis 8 | 6,694
glioblastoma 7 | 5,792
invasive ductal carcinoma 7 | 2,951
Atherosclerosis 6 | 291
lung adenocarcinoma 6 | 2,716
Arthritis 5 | 290
Brain Injuries 5 | 65
Breast cancer 5 | 3,578
Cerebrovascular disease 5 | 238
Liver Cirrhosis, Experimental 5 | 769
Neoplasm Metastasis 5 | 168
Obesity 5 | 678
Pneumonia 5 | 174
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
diabetes mellitus 5 | 1,728
group 3 medulloblastoma 5 | 4,104
lung carcinoma 5 | 2,843
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
Asthma 4 | 385
Astrocytoma, Pilocytic 4 | 3,081
Bipolar Disorder 4 | 666
Carcinoma, Non-Small-Cell Lung 4 | 107
Heart disease 4 | 306
Leukemia, Myelocytic, Acute 4 | 120
Leukemia, Myeloid, Acute 4 | 105
Multiple myeloma 4 | 1,332
Neurodegenerative disease 4 | 414
Prostatic Neoplasms 4 | 495
Pulmonary Fibrosis 4 | 106
Schizophrenia 4 | 1,160
Skin Neoplasms 4 | 69
Toxic encephalopathy 4 | 141
ependymoma 4 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
medulloblastoma, large-cell 4 | 6,241
non-small cell lung carcinoma 4 | 317
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Alzheimer's disease 3 | 658
Anemia 3 | 365
Autosomal recessive predisposition 3 | 1,442
Carcinoma, Hepatocellular 3 | 228
Carcinoma, Squamous Cell 3 | 110
Cerebral Hemorrhage 3 | 42
Colorectal Neoplasms 3 | 243
Coronary artery disease 3 | 268
Depressive disorder 3 | 409
Diabetes Mellitus, Experimental 3 | 108
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Endometriosis 3 | 540
Head and Neck Neoplasms 3 | 26
Heart Diseases 3 | 43
Heart failure 3 | 162
Hypersensitivity reaction type II disease 3 | 253
Hypertension 3 | 396
Inflammation 3 | 120
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Liver carcinoma 3 | 240
Melanoma 3 | 711
Myocardial Reperfusion Injury 3 | 37
Osteopetrosis 3 | 43
Osteoporosis 3 | 363
Retinal Diseases 3 | 55
Rheumatoid arthritis 3 | 1,191
Short stature 3 | 531
Squamous cell carcinoma 3 | 129
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
cystic fibrosis 3 | 1,696
hepatocellular carcinoma 3 | 547
interstitial cystitis 3 | 2,312
interstitial lung disease 3 | 298
subependymal giant cell astrocytoma 3 | 2,287
Brain Ischemia 2 | 110
Chronic obstructive pulmonary disease 2 | 184
Colonic Neoplasms 2 | 142
Dermatitis, Contact 2 | 71
Diabetes Mellitus, Type 2 2 | 142
Disease Models, Animal 2 | 155
Inflammatory bowel disease 2 | 151
Leukemia, Myeloid 2 | 18
Liver diseases 2 | 87
Mesothelioma, Malignant 2 | 105
Mood Disorders 2 | 184
Myeloid Leukemia 2 | 19
Neuropathy 2 | 261
Reperfusion Injury 2 | 86
Status Epilepticus 2 | 98
Type 2 diabetes mellitus 2 | 272

Tissue

Blood and immune system 18 | 16,909
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Liver and Pancreas 18 | 16,750
Skin and soft tissues 18 | 17,230
Female tissues 17 | 17,400
Respiratory system 17 | 16,393
Urinary Tract 17 | 16,678
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Cardiovascular System 15 | 15,192

Target Family

Non-IDG 6 | 12,091
Enzyme 4 | 4,145
Transcription Factor 4 | 1,400
Epigenetic 2 | 242
Kinase 2 | 634

GO Process

macrophage differentiation 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GRB2-associated-binding protein 3 GAB3 Tbio Non-IDG -0.78182 5.77 104
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
CCAAT/enhancer-binding protein alpha CEBPA Tbio Transcription Factor -2.94393 846.3 518
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Granulocyte colony-stimulating factor CSF3 Tbio Non-IDG -3.83212 6976.9 816
Homeobox protein Nkx-2.3 NKX2-3 Tbio Transcription Factor -1.47301 30.7 63
Macrophage colony-stimulating factor 1 receptor CSF1R Tclin Kinase -3.19109 1432.9 1169
Eukaryotic translation initiation factor 2-alpha kinase 1 EIF2AK1 Tchem Kinase -2.02167 96.7 226
CCAAT/enhancer-binding protein epsilon CEBPE Tbio Transcription Factor -1.71776 57.4 246
Caspase-8 CASP8 Tchem Enzyme -3.54224 3121.4 1045