Development Level

Tchem 5 | 1,388
Tbio 1 | 11,651
Tclin 1 | 612

IMPC Phenotype

abnormal gait 2 | 69
abnormal spine curvature 1 | 9
decreased circulating creatini... 1 | 39
decreased circulating magnesiu... 1 | 13
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
impaired righting response 1 | 26
increased lymphocyte cell numb... 1 | 32
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979

Disease

osteosarcoma 6 | 7,950
Carcinoma 5 | 11,493
ependymoma 5 | 4,679
Cancer 4 | 2,499
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Arthritis 3 | 290
Asthma 3 | 385
Astrocytoma, Pilocytic 3 | 3,081
Atherosclerosis 3 | 291
Atopic dermatitis 3 | 952
Carcinoma, Hepatocellular 3 | 228
Cerebrovascular disease 3 | 238
Colorectal Neoplasms 3 | 243
Inflammatory bowel disease 3 | 151
Liver Cirrhosis 3 | 181
Liver carcinoma 3 | 240
Lung disease 3 | 142
Osteoporosis 3 | 363
Schizophrenia 3 | 1,160
breast carcinoma 3 | 1,638
glioblastoma 3 | 5,792
group 4 medulloblastoma 3 | 1,855
hearing impairment 3 | 199
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
pancreatic cancer 3 | 2,398
Acquired scoliosis 2 | 281
Acute kidney injury 2 | 70
Adenocarcinoma 2 | 122
Alzheimer's disease 2 | 658
Bipolar Disorder 2 | 666
Breast cancer 2 | 3,578
Class III malocclusion 2 | 78
Congenital deafness 2 | 185
Coronary artery disease 2 | 268
Curvature of spine 2 | 282
Deafness 2 | 198
Delayed bone age 2 | 136
Dental caries 2 | 164
Diabetes Mellitus, Experimental 2 | 108
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Diabetic Nephropathies 2 | 37
Exophthalmos 2 | 112
Hearing Loss, Partial 2 | 185
Heart disease 2 | 306
Hepatitis C 2 | 94
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hirsutism 2 | 47
Hypersensitivity reaction type II disease 2 | 253
Hypertension 2 | 396
Hypertrophy of lower jaw 2 | 78
Immunologic Deficiency Syndromes 2 | 113
Increased size of mandible 2 | 78
Inflammation 2 | 120
Kidney Diseases 2 | 114
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Liver Cirrhosis, Experimental 2 | 769
Liver disease 2 | 237
Mandibular hyperplasia 2 | 78
Melanoma 2 | 711
Mood Disorders 2 | 184
Multiple Sclerosis 2 | 540
Neoplasm Metastasis 2 | 168
Neurodegenerative disease 2 | 414
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Phenotypic variability 2 | 150
Prominent eyes 2 | 96
Prominent globes 2 | 96
Protruding eyes 2 | 96
Recurrent respiratory infections 2 | 141
Recurrent upper respiratory tract infection 2 | 21
Squamous cell carcinoma 2 | 129
Stomach Neoplasms 2 | 300
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
mandibular excess (physical finding) 2 | 78
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
sarcoidosis 2 | 370
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 7 | 16,909
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678
Cardiovascular System 6 | 15,192
Nervous System 6 | 16,725

Target Family

Enzyme 2 | 4,145
Non-IDG 2 | 12,091
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

GO Process

macrophage derived foam cell d... 7 | 7
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Peroxisome proliferator-activated receptor gamma PPARG Tclin Nuclear Receptor -3.96393 9579.5 773
Histone acetyltransferase p300 EP300 Tchem Epigenetic -3.79743 6016.7 775
Sterol O-acyltransferase 1 SOAT1 Tchem Enzyme -2.14394 138.3 129
Sterol O-acyltransferase 2 SOAT2 Tchem Enzyme -1.60747 40.5 68
Selenoprotein K SELENOK Tbio Non-IDG -1.39537 26.6 0
Signal transducer and activator of transcription 1-alpha/beta STAT1 Tchem Transcription Factor -3.33049 2009.0 1596