Development Level

Tbio 77 | 11,445
Tchem 10 | 1,598
Tdark 7 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 16 | 979
abnormal behavior 6 | 298
hypoactivity 4 | 132
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
decreased mean platelet volume 3 | 25
embryonic lethality prior to o... 3 | 239
enlarged spleen 3 | 41
abnormal body wall morphology 2 | 9
cataract 2 | 92
decreased circulating glucose ... 2 | 126
decreased circulating magnesiu... 2 | 13
decreased circulating serum al... 2 | 82
decreased mean corpuscular hem... 2 | 50
decreased total retina thickne... 2 | 17
impaired glucose tolerance 2 | 75
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased mean platelet volume 2 | 45
increased red blood cell distr... 2 | 34
increased startle reflex 2 | 112
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal thymus morphology 1 | 7
absent startle reflex 1 | 24
anophthalmia 1 | 33
aorta dilation 1 | 3
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged thymus 1 | 5
hyperactivity 1 | 148
increased body length 1 | 32
increased circulating alanine ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating glycerol... 1 | 9
increased circulating serum al... 1 | 22
increased fasted circulating g... 1 | 76
increased glycosylated hemoglo... 1 | 1
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
protruding tongue 1 | 3
short tibia 1 | 97
shortened QT interval 1 | 4
thrombocytopenia 1 | 56

Disease

ovarian cancer 62 | 8,520
Carcinoma 46 | 11,493
osteosarcoma 45 | 7,950
medulloblastoma, large-cell 33 | 6,241
psoriasis 32 | 6,694
lung cancer 28 | 4,740
glioblastoma 23 | 5,792
atypical teratoid / rhabdoid tumor 22 | 5,112
Multiple myeloma 20 | 1,332
Cancer 17 | 2,499
Breast cancer 13 | 3,578
ependymoma 13 | 4,679
adult high grade glioma 12 | 3,801
group 4 medulloblastoma 12 | 1,855
subependymal giant cell astrocytoma 12 | 2,287
Neurodegenerative disease 11 | 414
astrocytic glioma 11 | 2,597
oligodendroglioma 11 | 2,850
spina bifida 11 | 1,074
diabetes mellitus 10 | 1,728
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
malignant mesothelioma 9 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Kidney cancer 8 | 2,613
Pick disease 8 | 1,894
primitive neuroectodermal tumor 8 | 3,035
tuberculosis 8 | 2,010
Schizophrenia 7 | 1,160
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
progressive supranuclear palsy 7 | 676
Alzheimer's disease 6 | 658
Astrocytoma, Pilocytic 6 | 3,081
Waldenstrons macroglobulinemia 6 | 765
acute myeloid leukemia 6 | 783
astrocytoma 6 | 1,146
breast carcinoma 6 | 1,638
dermatomyositis 6 | 966
hepatocellular carcinoma 6 | 547
juvenile dermatomyositis 6 | 1,187
Amyotrophic lateral sclerosis 5 | 451
Anemia 5 | 365
Autosomal recessive predisposition 5 | 1,442
Nerve Degeneration 5 | 121
Vascular disease 5 | 319
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pancreatic cancer 5 | 2,398
pituitary cancer 5 | 1,972
primary pancreatic ductal adenocarcinoma 5 | 1,109
Anxiety 4 | 136
Anxiety disease 4 | 113
Cardiomegaly 4 | 116
Centronuclear myopathy 4 | 27
Crohn's disease 4 | 321
Dementia 4 | 175
Dysarthria 4 | 192
Epilepsy 4 | 792
Gait abnormality 4 | 135
Gaucher disease type 1 4 | 180
Optic Atrophy 4 | 242
Ovarian Neoplasms 4 | 102
Pain 4 | 103
Rheumatoid arthritis 4 | 1,191
Stomach Neoplasms 4 | 300
Vici syndrome 4 | 14
acute quadriplegic myopathy 4 | 1,158
colon cancer 4 | 1,478
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
medulloblastoma 4 | 720
non primary Sjogren syndrome sicca 4 | 891
posterior fossa group A ependymoma 4 | 468
Aggressive behavior 3 | 75
Aggressive reaction 3 | 75
Atopic dermatitis 3 | 952
Babinski Reflex 3 | 100
Breast Neoplasms 3 | 445
Cerebral atrophy 3 | 178
Colonic Neoplasms 3 | 142
Decreased tendon reflex 3 | 122
Dystonia 3 | 164
Dystonic disease 3 | 106
Frontotemporal dementia 3 | 51
Generalized muscle weakness 3 | 57
Heart disease 3 | 306
Hepatomegaly 3 | 285
Hyperreflexia 3 | 209
Lung Neoplasms 3 | 232
Muscle Spasticity 3 | 195
Neurogenic Muscular Atrophy 3 | 139
Neurogenic muscle atrophy, especially in the lower limbs 3 | 139
Personality change 3 | 23
Physical aggression 3 | 76
Respiratory Failure 3 | 104
Seizures 3 | 596
Skeletal muscle atrophy 3 | 139
muscle degeneration 3 | 139
tuberculosis and treatment for 6 months 3 | 409

Tissue

Cardiovascular System 95 | 15,192
Digestive Tract 95 | 17,369
Endocrine System 95 | 18,159
Female tissues 95 | 17,400
Male tissues 95 | 17,142
Skin and soft tissues 95 | 17,230
Blood and immune system 94 | 16,909
Liver and Pancreas 94 | 16,750
Nervous System 94 | 16,725
Respiratory system 94 | 16,393
Urinary Tract 94 | 16,678

Target Family

Non-IDG 70 | 12,091
Enzyme 13 | 4,145
Kinase 12 | 634

GO Process

macroautophagy 95 | 95
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myotubularin-related protein 3 MTMR3 Tbio Enzyme -1.05980 10.7 33
Cysteine protease ATG4B ATG4B Tbio Enzyme -1.79492 58.3 416
Transmembrane protein 74 TMEM74 Tdark Non-IDG -0.72496 3.54 52
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Charged multivesicular body protein 3 CHMP3 Tbio Non-IDG -1.39658 35.6 64
Charged multivesicular body protein 4a CHMP4A Tbio Non-IDG -1.17768 16.3 29
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Ubiquilin-1 UBQLN1 Tbio Non-IDG -1.92650 87.0 256
Mitochondrial import receptor subunit TOM70 TOMM70 Tbio Non-IDG -1.78206 61.0 172