Development Level

Tbio 197 | 11,651
Tdark 33 | 6,593
Tchem 6 | 1,388

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 32 | 979
embryonic lethality prior to o... 12 | 239
embryonic lethality prior to t... 7 | 278
abnormal behavior 5 | 298
prenatal lethality prior to he... 4 | 87
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
decreased bone mineral density 3 | 126
decreased leukocyte cell numbe... 3 | 73
decreased lymphocyte cell numb... 3 | 83
decreased neutrophil cell numb... 3 | 42
hypoactivity 3 | 132
increased fasted circulating g... 3 | 76
increased lean body mass 3 | 172
increased mean corpuscular vol... 3 | 92
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
decreased circulating triglyce... 2 | 79
decreased mean corpuscular hem... 2 | 31
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating free fat... 2 | 20
increased lymphocyte cell numb... 2 | 32
increased mean platelet volume 2 | 45
increased total body fat amoun... 2 | 134
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal chorioallantoic fusio... 1 | 8
abnormal esophagus morphology 1 | 5
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal pancreas morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal retinal vasculature m... 1 | 27
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased startle reflex 1 | 75
decreased urine magnesium leve... 1 | 3
edema 1 | 59
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
male infertility 1 | 123
short tibia 1 | 97
thrombocytosis 1 | 27

Disease

ovarian cancer 158 | 8,520
Carcinoma 149 | 11,493
osteosarcoma 111 | 7,950
group 3 medulloblastoma 86 | 4,104
psoriasis 81 | 6,694
medulloblastoma, large-cell 79 | 6,241
lung cancer 76 | 4,740
glioblastoma 72 | 5,792
Multiple myeloma 63 | 1,332
ependymoma 55 | 4,679
atypical teratoid / rhabdoid tumor 54 | 5,112
malignant mesothelioma 49 | 3,232
oligodendroglioma 48 | 2,850
Breast cancer 42 | 3,578
primitive neuroectodermal tumor 39 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 38 | 2,989
acute quadriplegic myopathy 37 | 1,158
astrocytic glioma 35 | 2,597
Kidney cancer 34 | 2,613
Waldenstrons macroglobulinemia 34 | 765
dermatomyositis 33 | 966
astrocytoma 32 | 1,146
diabetes mellitus 31 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
Pick disease 29 | 1,894
adult high grade glioma 28 | 3,801
lung adenocarcinoma 26 | 2,716
subependymal giant cell astrocytoma 25 | 2,287
non-small cell lung cancer 24 | 2,890
Intellectual disability 22 | 1,016
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
progressive supranuclear palsy 21 | 676
Cancer 20 | 2,499
acute myeloid leukemia 19 | 783
invasive ductal carcinoma 19 | 2,951
juvenile dermatomyositis 17 | 1,187
pediatric high grade glioma 16 | 1,064
breast carcinoma 15 | 1,638
group 4 medulloblastoma 15 | 1,855
non primary Sjogren syndrome sicca 15 | 891
pancreatic cancer 14 | 2,398
Amyotrophic lateral sclerosis 13 | 451
Dull intelligence 13 | 645
Gaucher disease type 1 13 | 180
Low intelligence 13 | 645
Mental Retardation 13 | 645
Mental deficiency 13 | 645
Poor school performance 13 | 645
hepatocellular carcinoma 13 | 547
tuberculosis and treatment for 6 months 13 | 409
Rheumatoid arthritis 11 | 1,191
Conductive hearing loss 10 | 123
atypical teratoid/rhabdoid tumor 10 | 357
pituitary cancer 10 | 1,972
Astrocytoma, Pilocytic 9 | 3,081
Broad flat nasal bridge 9 | 236
Nasal bridge wide 9 | 236
adrenocortical carcinoma 9 | 1,428
aldosterone-producing adenoma 9 | 665
nasopharyngeal carcinoma 9 | 1,058
relapsing-remitting multiple sclerosis 9 | 18
Anteverted nostril 8 | 191
Retinitis Pigmentosa 8 | 226
colon cancer 8 | 1,478
spina bifida 8 | 1,074
Abnormality of the retinal vasculature 7 | 59
Blind Vision 7 | 111
Blindness, Legal 7 | 110
Cataract 7 | 297
Cleft Palate 7 | 271
Epilepsy 7 | 792
Glaucoma 7 | 239
HIV Infections 7 | 102
Keratoconus 7 | 113
Lens Opacities 7 | 231
Nystagmus 7 | 317
Obesity 7 | 678
Ophthalmoplegia 7 | 106
Polycystic ovary syndrome 7 | 360
Sensorineural Hearing Loss (disorder) 7 | 284
Short stature 7 | 531
Small head 7 | 374
Uranostaphyloschisis 7 | 167
pancreatic carcinoma 7 | 562
Autosomal recessive predisposition 6 | 1,442
Cognitive delay 6 | 608
Congenital hypoplasia of penis 6 | 176
Electroretinogram abnormal 6 | 95
Global developmental delay 6 | 608
Hypoplastic mandible condyle 6 | 275
Mandibular hypoplasia 6 | 275
Mental and motor retardation 6 | 608
Microcephaly 6 | 166
Optic Atrophy 6 | 242
Schizophrenia 6 | 1,160
Stomach Neoplasms 6 | 300
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
gastric cancer 6 | 459
tuberculosis 6 | 2,010

Tissue

Blood and immune system 235 | 16,909
Digestive Tract 235 | 17,369
Endocrine System 235 | 18,159
Female tissues 235 | 17,400
Liver and Pancreas 235 | 16,750
Male tissues 234 | 17,142
Respiratory system 234 | 16,393
Skin and soft tissues 234 | 17,230
Urinary Tract 234 | 16,678
Cardiovascular System 233 | 15,192
Nervous System 233 | 16,725

Target Family

Non-IDG 191 | 12,091
Enzyme 40 | 4,145
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
Kinase 1 | 634

GO Process

mRNA splicing, via spliceosome 236 | 236
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paraspeckle component 1 PSPC1 Tbio Non-IDG -1.75415 48.3 19
Pre-mRNA-splicing factor CWC25 homolog CWC25 Tdark Non-IDG -0.71222 5.53 18
Heterogeneous nuclear ribonucleoprotein A0 HNRNPA0 Tbio Non-IDG -0.86935 6.45 110
U6 snRNA-associated Sm-like protein LSm5 LSM5 Tdark Non-IDG -0.98876 8.80 46
Pre-mRNA-splicing factor SYF2 SYF2 Tbio Non-IDG -1.04825 13.2 124
Probable ATP-dependent RNA helicase DDX23 DDX23 Tbio Enzyme -1.24669 18.6 167
Gem-associated protein 6 GEMIN6 Tbio Non-IDG -1.28961 17.2 110
U4/U6 small nuclear ribonucleoprotein Prp31 PRPF31 Tbio Non-IDG -1.84397 72.4 216
Putative small nuclear ribonucleoprotein G-like protein 15 SNRPGP15 Tdark Non-IDG 0.12 1.33 0
Heterogeneous nuclear ribonucleoprotein H HNRNPH1 Tbio Non-IDG -1.71562 50.9 205