Development Level

Tbio 131 | 11,651
Tdark 30 | 6,593
Tchem 7 | 1,388

Collection

Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 22 | 979
embryonic lethality prior to t... 8 | 278
embryonic lethality prior to o... 6 | 239
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
abnormal embryo size 4 | 220
abnormal coat-hair pigmentatio... 3 | 64
abnormal sleep behavior 3 | 70
decreased grip strength 3 | 116
embryonic growth retardation 3 | 106
hyperactivity 3 | 148
increased startle reflex 3 | 112
cataract 2 | 92
decreased circulating alkaline... 2 | 46
decreased mean corpuscular hem... 2 | 31
decreased neutrophil cell numb... 2 | 42
decreased vertical activity 2 | 208
hypoactivity 2 | 132
increased lymphocyte cell numb... 2 | 32
abnormal bone structure 1 | 187
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal spleen morphology 1 | 55
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
aorta dilation 1 | 3
decreased IgE level 1 | 6
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
impaired righting response 1 | 26
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
small kidney 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 121 | 11,493
ovarian cancer 111 | 8,520
osteosarcoma 85 | 7,950
medulloblastoma, large-cell 68 | 6,241
atypical teratoid / rhabdoid tumor 58 | 5,112
glioblastoma 57 | 5,792
ependymoma 56 | 4,679
psoriasis 56 | 6,694
group 3 medulloblastoma 53 | 4,104
lung cancer 47 | 4,740
oligodendroglioma 43 | 2,850
adult high grade glioma 38 | 3,801
primitive neuroectodermal tumor 37 | 3,035
astrocytic glioma 36 | 2,597
acute quadriplegic myopathy 35 | 1,158
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
Pick disease 30 | 1,894
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 29 | 1,962
Kidney cancer 28 | 2,613
Multiple myeloma 25 | 1,332
juvenile dermatomyositis 25 | 1,187
Astrocytoma, Pilocytic 24 | 3,081
Breast cancer 24 | 3,578
astrocytoma 23 | 1,146
dermatomyositis 23 | 966
malignant mesothelioma 22 | 3,232
progressive supranuclear palsy 21 | 676
subependymal giant cell astrocytoma 21 | 2,287
lung adenocarcinoma 20 | 2,716
diabetes mellitus 18 | 1,728
Cancer 17 | 2,499
Waldenstrons macroglobulinemia 17 | 765
non-small cell lung cancer 17 | 2,890
pancreatic cancer 17 | 2,398
colon cancer 13 | 1,478
group 4 medulloblastoma 13 | 1,855
invasive ductal carcinoma 13 | 2,951
Rheumatoid arthritis 12 | 1,191
lung carcinoma 12 | 2,843
pituitary cancer 12 | 1,972
Intellectual disability 11 | 1,016
pediatric high grade glioma 11 | 1,064
tuberculosis 11 | 2,010
Amyotrophic lateral sclerosis 10 | 451
breast carcinoma 10 | 1,638
tuberculosis and treatment for 6 months 10 | 409
Alzheimer's disease 9 | 658
Schizophrenia 9 | 1,160
acute myeloid leukemia 9 | 783
non primary Sjogren syndrome sicca 9 | 891
primary pancreatic ductal adenocarcinoma 9 | 1,109
spina bifida 9 | 1,074
relapsing-remitting multiple sclerosis 8 | 18
Neurodegenerative disease 7 | 414
aldosterone-producing adenoma 7 | 665
nasopharyngeal carcinoma 7 | 1,058
Depressive disorder 6 | 409
Duchenne muscular dystrophy 6 | 601
Gaucher disease type 1 6 | 180
HIV Infections 6 | 102
Neurogenic Muscular Atrophy 6 | 139
Neurogenic muscle atrophy, especially in the lower limbs 6 | 139
Skeletal muscle atrophy 6 | 139
Spinal muscular atrophy 6 | 34
adrenocortical carcinoma 6 | 1,428
cystic fibrosis 6 | 1,696
muscle degeneration 6 | 139
ulcerative colitis 6 | 1,819
Dull intelligence 5 | 645
Hypogonadism 5 | 173
Low intelligence 5 | 645
Melanoma 5 | 711
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Microcephaly 5 | 166
Muscular atrophy 5 | 71
Poor school performance 5 | 645
atypical teratoid/rhabdoid tumor 5 | 357
gastric carcinoma 5 | 807
Anteverted nostril 4 | 191
Atherosclerosis 4 | 291
Cognitive delay 4 | 608
Down syndrome 4 | 499
Epilepsy 4 | 792
Global developmental delay 4 | 608
Huntington's disease 4 | 76
Liver Cirrhosis, Experimental 4 | 769
Liver cancer 4 | 604
Mental and motor retardation 4 | 608
Muscle Spasticity 4 | 195
Polycystic ovary syndrome 4 | 360
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
ductal carcinoma in situ 4 | 1,745
medulloblastoma 4 | 720
pancreatic carcinoma 4 | 562
posterior fossa group B ependymoma 4 | 416
primary Sjogren syndrome 4 | 735
sonic hedgehog group medulloblastoma 4 | 467

Tissue

Endocrine System 166 | 18,159
Digestive Tract 162 | 17,369
Female tissues 162 | 17,400
Skin and soft tissues 161 | 17,230
Male tissues 160 | 17,142
Nervous System 159 | 16,725
Respiratory system 158 | 16,393
Liver and Pancreas 157 | 16,750
Urinary Tract 157 | 16,678
Blood and immune system 156 | 16,909
Cardiovascular System 153 | 15,192

Target Family

Non-IDG 125 | 12,091
Enzyme 32 | 4,145
Kinase 5 | 634
Epigenetic 3 | 242
Transcription Factor 3 | 1,400

GO Process

mRNA processing 168 | 168
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DBIRD complex subunit ZNF326 ZNF326 Tbio Non-IDG -0.42207 3.94 120
RNA-binding protein 39 RBM39 Tbio Non-IDG -0.95639 9.80 199
Heterogeneous nuclear ribonucleoprotein A0 HNRNPA0 Tbio Non-IDG -0.86935 6.45 110
U6 snRNA-associated Sm-like protein LSm5 LSM5 Tdark Non-IDG -0.98876 8.80 46
Nocturnin NOCT Tbio Non-IDG -1.84562 69.3 92
RNA binding protein fox-1 homolog 1 RBFOX1 Tbio Non-IDG -2.00815 99.2 207
Protein ecdysoneless homolog ECD Tbio Non-IDG -0.72245 9.93 113
Mitochondrial mRNA pseudouridine synthase TRUB2 TRUB2 Tdark Enzyme 0.08 0.76 124
Corepressor interacting with RBPJ 1 CIR1 Tdark Non-IDG -0.30821 2.08 91
Serine/threonine-protein phosphatase 4 regulatory subunit 2 PPP4R2 Tbio Enzyme -0.78829 5.38 130