Development Level

Tbio 107 | 10,625
Tdark 41 | 7,003
Tchem 14 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 11 | 633
embryonic lethality prior to o... 4 | 148
embryonic lethality prior to t... 4 | 187
decreased grip strength 3 | 123
abnormal behavior 2 | 226
abnormal coat/hair pigmentatio... 2 | 54
hyperactivity 2 | 108
increased circulating HDL chol... 2 | 63
increased or absent threshold ... 2 | 128
preweaning lethality, incomple... 2 | 260
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal neural tube closure 1 | 37
abnormal neural tube morpholog... 1 | 8
abnormal placenta size 1 | 10
abnormal retinal outer nuclear... 1 | 5
abnormal sleep behavior 1 | 63
abnormal vocalization 1 | 21
absent startle reflex 1 | 15
aorta dilation 1 | 3
decreased IgG2b level 1 | 1
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating alkaline... 1 | 41
decreased circulating fructosa... 1 | 31
decreased heart left ventricle... 1 | 2
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased lymphocyte cell numb... 1 | 9
decreased memory-marker CD4-ne... 1 | 4
decreased neutrophil cell numb... 1 | 37
immune system phenotype 1 | 17
improved glucose tolerance 1 | 56
increased CD4-negative NK T ce... 1 | 4
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
pale yolk sac 1 | 12
pallor 1 | 13
thrombocytosis 1 | 23

Disease

ovarian cancer 107 | 8,484
osteosarcoma 83 | 7,933
medulloblastoma, large-cell 63 | 6,234
psoriasis 54 | 6,685
glioblastoma 52 | 5,572
atypical teratoid / rhabdoid tumor 45 | 4,369
lung cancer 45 | 4,466
oligodendroglioma 41 | 2,849
ependymoma 40 | 2,514
group 3 medulloblastoma 36 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 36 | 2,988
primitive neuroectodermal tumor 35 | 3,031
acute quadriplegic myopathy 34 | 1,157
intraductal papillary-mucinous adenoma (IPMA) 32 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,289
Pick disease 29 | 1,893
astrocytoma 28 | 1,493
pancreatic ductal adenocarcinoma liver metastasis 27 | 1,795
astrocytic glioma 26 | 2,241
Breast cancer 24 | 3,094
Multiple myeloma 24 | 1,327
adult high grade glioma 24 | 2,148
dermatomyositis 24 | 933
juvenile dermatomyositis 24 | 1,189
lung adenocarcinoma 23 | 2,713
Carcinoma 22 | 2,147
malignant mesothelioma 22 | 3,162
pediatric high grade glioma 21 | 2,712
pilocytic astrocytoma 21 | 3,086
subependymal giant cell astrocytoma 21 | 2,287
progressive supranuclear palsy 20 | 674
non-small cell lung cancer 19 | 2,798
Waldenstrons macroglobulinemia 18 | 765
diabetes mellitus 17 | 1,663
group 4 medulloblastoma 17 | 1,875
pancreatic cancer 17 | 2,300
Cancer 15 | 2,346
atypical teratoid/rhabdoid tumor 14 | 1,095
invasive ductal carcinoma 13 | 2,950
tuberculosis and treatment for 6 months 13 | 686
colon cancer 12 | 1,475
Rheumatoid Arthritis 11 | 1,160
lung carcinoma 11 | 2,844
pituitary cancer 11 | 1,972
sonic hedgehog group medulloblastoma 11 | 1,482
Amyotrophic Lateral Sclerosis 10 | 431
breast carcinoma 10 | 1,614
posterior fossa group B ependymoma 10 | 1,530
primary pancreatic ductal adenocarcinoma 10 | 1,271
Alzheimer's disease 9 | 644
Intellectual disability 9 | 573
acute myeloid leukemia 9 | 780
non primary Sjogren syndrome sicca 9 | 840
posterior fossa group A ependymoma 9 | 1,511
Neurodegenerative disease 8 | 383
nasopharyngeal carcinoma 8 | 1,056
spina bifida 8 | 1,064
relapsing-remitting multiple sclerosis 7 | 18
Duchenne muscular dystrophy 6 | 602
HIV Infections 6 | 100
Microcephaly 6 | 149
cystic fibrosis 6 | 1,665
ductal carcinoma in situ 6 | 1,745
tuberculosis 6 | 1,557
ulcerative colitis 6 | 2,087
Gaucher disease type 1 5 | 171
Muscular atrophy 5 | 67
Myotonic dystrophy type 1 5 | 16
Schizophrenia 5 | 501
adrenocortical carcinoma 5 | 1,427
aldosterone-producing adenoma 5 | 664
medulloblastoma 5 | 1,524
primary Sjogren syndrome 5 | 789
Azoospermia 4 | 89
Down syndrome 4 | 548
IGA Glomerulonephritis 4 | 454
Polycystic Ovary Syndrome 4 | 332
Pontocerebellar hypoplasia 4 | 29
Spinal muscular atrophy 4 | 24
active Crohn's disease 4 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 499
gastric carcinoma 4 | 832
hepatocellular carcinoma 4 | 532
pancreatic carcinoma 4 | 567
Animal Mammary Neoplasms 3 | 136
Atopic dermatitis 3 | 944
Epilepsy 3 | 346
Infertility 3 | 163
Mammary Neoplasms, Experimental 3 | 150
Movement Disorders 3 | 21
Obesity 3 | 616
Peripheral Neuropathy 3 | 303
Vision Disorders 3 | 5
active ulcerative colitis 3 | 477
gastric cancer 3 | 430
glioblastoma multiforme 3 | 347
hereditary spastic paraplegia 3 | 313
interstitial cystitis 3 | 2,299
mucosa-associated lymphoid tissue lymphoma 3 | 480
tuberculosis and treatment for 3 months 3 | 327

Tissue

Female tissues 161 | 18,647
Male tissues 160 | 17,969
Blood and immune system 159 | 17,995
Endocrine System 158 | 18,512
Digestive Tract 155 | 18,473
Urinary Tract 155 | 18,444
Cardiovascular System 153 | 17,958
Liver and Pancreas 153 | 18,136
Nervous System 153 | 18,561
Respiratory system 153 | 17,484
Skin and soft tissues 151 | 18,115

Target Family

Non-IDG 123 | 11,971
Enzyme 27 | 4,146
Kinase 6 | 634
Epigenetic 4 | 242
Transcription Factor 2 | 1,400

GO Process

mRNA processing 162 | 162
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 368 | 368
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
MAPK cascade 238 | 238
chemical synaptic transmission 238 | 238
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 200 | 200
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 181 | 181
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 176 | 176
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
negative regulation of canonic... 162 | 162
protein folding 162 | 162
T cell receptor signaling path... 161 | 161
response to lipopolysaccharide 161 | 161
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2/M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
antigen processing and present... 130 | 130
type I interferon signaling pa... 130 | 130

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Pre-mRNA-splicing factor 38A PRPF38A Tdark Non-IDG -0.69167 4.80 72
Putative RNA-binding protein 15B RBM15B Tbio Non-IDG -0.27107 2.59 18
SURP and G-patch domain-containing protein 2 SUGP2 Tdark Non-IDG 0.12 0.80 116
Complement component 1 Q subcomponent-binding protein, mitochondrial C1QBP Tbio Non-IDG -2.51978 332.6 298
Cleavage and polyadenylation specificity factor subunit 5 NUDT21 Tbio Non-IDG -1.49160 28.8 100
Pre-mRNA-processing-splicing factor 8 PRPF8 Tbio Non-IDG -1.76142 60.3 76
Splicing factor, proline- and glutamine-rich SFPQ Tbio Non-IDG -1.58414 31.4 210
Nuclear speckle splicing regulatory protein 1 NSRP1 Tbio Non-IDG -0.79239 6.65 77
5'-3' exoribonuclease 2 XRN2 Tbio Enzyme -1.48143 31.3 110