Development Level

Tbio 91 | 11,445
Tdark 8 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 16 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 34
decreased fasted circulating g... 1 | 65
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged heart 1 | 210
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 72 | 11,493
ovarian cancer 58 | 8,520
osteosarcoma 48 | 7,950
group 3 medulloblastoma 43 | 4,104
medulloblastoma, large-cell 42 | 6,241
lung cancer 41 | 4,740
glioblastoma 30 | 5,792
psoriasis 28 | 6,694
atypical teratoid / rhabdoid tumor 26 | 5,112
Breast cancer 23 | 3,578
Kidney cancer 22 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
primitive neuroectodermal tumor 21 | 3,035
ependymoma 19 | 4,679
Multiple myeloma 18 | 1,332
acute quadriplegic myopathy 18 | 1,158
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
malignant mesothelioma 18 | 3,232
non-small cell lung cancer 17 | 2,890
oligodendroglioma 17 | 2,850
Waldenstrons macroglobulinemia 15 | 765
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
adult high grade glioma 14 | 3,801
astrocytic glioma 14 | 2,597
Pick disease 13 | 1,894
dermatomyositis 13 | 966
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
invasive ductal carcinoma 11 | 2,951
Cancer 10 | 2,499
lung adenocarcinoma 10 | 2,716
subependymal giant cell astrocytoma 10 | 2,287
astrocytoma 9 | 1,146
Astrocytoma, Pilocytic 8 | 3,081
pancreatic cancer 8 | 2,398
progressive supranuclear palsy 8 | 676
Amyotrophic lateral sclerosis 7 | 451
Intellectual disability 7 | 1,016
breast carcinoma 7 | 1,638
colon cancer 7 | 1,478
group 4 medulloblastoma 7 | 1,855
tuberculosis 7 | 2,010
tuberculosis and treatment for 6 months 7 | 409
Autosomal recessive predisposition 6 | 1,442
Rheumatoid arthritis 6 | 1,191
acute myeloid leukemia 6 | 783
diabetes mellitus 6 | 1,728
juvenile dermatomyositis 6 | 1,187
nasopharyngeal carcinoma 6 | 1,058
pediatric high grade glioma 6 | 1,064
spina bifida 6 | 1,074
Gaucher disease type 1 5 | 180
HIV Infections 5 | 102
adrenocortical carcinoma 5 | 1,428
aldosterone-producing adenoma 5 | 665
hepatocellular carcinoma 5 | 547
pancreatic carcinoma 5 | 562
Atopic dermatitis 4 | 952
Polycystic ovary syndrome 4 | 360
gastric cancer 4 | 459
interstitial cystitis 4 | 2,312
lung carcinoma 4 | 2,843
non primary Sjogren syndrome sicca 4 | 891
posterior fossa group B ependymoma 4 | 416
primary pancreatic ductal adenocarcinoma 4 | 1,109
sonic hedgehog group medulloblastoma 4 | 467
ulcerative colitis 4 | 1,819
Acquired immunodeficiency syndrome 3 | 197
Dull intelligence 3 | 645
Endometrial cancer 3 | 311
Leukemia 3 | 104
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Microcephaly 3 | 166
Osteoporosis 3 | 363
Poor school performance 3 | 645
Schizophrenia 3 | 1,160
Short stature 3 | 531
Anemia 2 | 365
Autistic Disorder 2 | 364
Bilateral fifth finger clinodactyly 2 | 110
Bipolar Disorder 2 | 666
Curvature of little finger 2 | 110
Disease Progression 2 | 136
Epilepsy 2 | 792
Hepatitis B 2 | 108
Liver cancer 2 | 604
Male infertility 2 | 206
Mastocytosis 2 | 27
Seizures 2 | 596
Stomach Neoplasms 2 | 300
active ulcerative colitis 2 | 764
atypical teratoid/rhabdoid tumor 2 | 357
cutaneous lupus erythematosus 2 | 1,057
hereditary spastic paraplegia 2 | 318
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
muscle degeneration 2 | 139
pituitary cancer 2 | 1,972
tuberculosis and treatment for 3 months 2 | 179

Tissue

Male tissues 99 | 17,142
Blood and immune system 98 | 16,909
Digestive Tract 98 | 17,369
Endocrine System 98 | 18,159
Female tissues 98 | 17,400
Nervous System 98 | 16,725
Respiratory system 98 | 16,393
Liver and Pancreas 97 | 16,750
Skin and soft tissues 97 | 17,230
Urinary Tract 97 | 16,678
Cardiovascular System 96 | 15,192

Target Family

Non-IDG 89 | 12,091
Enzyme 10 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

mRNA export from nucleus 101 | 101
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NTF2-related export protein 1 NXT1 Tbio Non-IDG -1.49831 29.4 91
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
THO complex subunit 7 homolog THOC7 Tbio Non-IDG -0.34772 2.04 61
THO complex subunit 5 homolog THOC5 Tbio Non-IDG -1.14189 16.8 116
Serine/threonine-protein kinase SMG1 SMG1 Tchem Kinase -1.61615 60.9 195
Cleavage and polyadenylation specificity factor subunit 3 CPSF3 Tbio Non-IDG -1.47182 27.3 190
THO complex subunit 6 homolog THOC6 Tbio Non-IDG -1.77416 57.9 131
Telomerase-binding protein EST1A SMG6 Tbio Enzyme -1.48788 32.6 37
Splicing factor U2AF 26 kDa subunit U2AF1L4 Tbio Non-IDG -0.17609 1.86 61