Development Level

Tbio 16 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal rib morphology 1 | 10
abnormal vitreous body morphol... 1 | 10
decreased bone mineral density 1 | 126
decreased mean corpuscular vol... 1 | 79
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
female infertility 1 | 60
increased bone mineral content 1 | 108
increased grip strength 1 | 41
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
male infertility 1 | 123

Disease

osteosarcoma 13 | 7,950
Carcinoma 11 | 11,493
ovarian cancer 10 | 8,520
psoriasis 8 | 6,694
group 3 medulloblastoma 7 | 4,104
medulloblastoma, large-cell 7 | 6,241
atypical teratoid / rhabdoid tumor 6 | 5,112
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung cancer 5 | 4,740
oligodendroglioma 5 | 2,850
pituitary cancer 5 | 1,972
Pick disease 4 | 1,894
Waldenstrons macroglobulinemia 4 | 765
adrenocortical carcinoma 4 | 1,428
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
pancreatic cancer 4 | 2,398
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Rheumatoid arthritis 3 | 1,191
astrocytoma 3 | 1,146
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Amyotrophic lateral sclerosis 2 | 451
Dental pulp necrosis 2 | 10
acute quadriplegic myopathy 2 | 1,158
aldosterone-producing adenoma 2 | 665
cystic fibrosis and chronic rhinosinusitis 2 | 214
dermatomyositis 2 | 966
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
non-small cell lung cancer 2 | 2,890
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
Alopecia 1 | 115
Arsenic Poisoning 1 | 62
Arthritis 1 | 290
Atherosclerosis 1 | 291
Breast Neoplasms 1 | 445
Burning mouth syndrome 1 | 7
Carcinoma, Hepatocellular 1 | 228
Colorectal Neoplasms 1 | 243
Coronary artery disease 1 | 268
Dermatitis 1 | 157
Dermatologic disorders 1 | 93
Down syndrome 1 | 499
Endometriosis 1 | 540
Epilepsy 1 | 792
Gyrate atrophy 1 | 7
Hyperplasia 1 | 27
Infertility 1 | 188
Infertility, Male 1 | 46
Inflammation 1 | 120
Liver Cirrhosis, Experimental 1 | 769
Liver carcinoma 1 | 240
Major Depressive Disorder 1 | 301
Male infertility 1 | 206
Mammary Neoplasms 1 | 425
Myocardial Ischemia 1 | 169
Neoplasm Invasiveness 1 | 161
Neutropenia 1 | 72
Nonsyndromic deafness 1 | 142
Skin Diseases 1 | 71
Thrombocytopenia 1 | 197
Trichorhinophalangeal syndrome type II 1 | 15
Unipolar Depression 1 | 250
X-linked cerebral adrenoleukodystrophy 1 | 116
Yellow fever 1 | 16
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adrenocortical adenoma 1 | 131
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
breast carcinoma 1 | 1,638
chronic lymphosyte leukemia 1 | 204
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
cystic fibrosis 1 | 1,696
esophageal adenocarcinoma 1 | 737
fascioscapulohumeral muscular dystrophy 1 | 100
fibroadenoma 1 | 559
hepatocellular carcinoma 1 | 547
hereditary spastic paraplegia 1 | 318
interstitial lung disease 1 | 298
nasopharyngeal carcinoma 1 | 1,058
nephrosclerosis 1 | 333
pancreatic carcinoma 1 | 562
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
sarcoidosis 1 | 370
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis and treatment for 6 months 1 | 409
urothelial carcinoma 1 | 318

Tissue

Endocrine System 18 | 18,159
Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Female tissues 17 | 17,400
Male tissues 17 | 17,142
Respiratory system 17 | 16,393
Cardiovascular System 16 | 15,192
Liver and Pancreas 16 | 16,750
Nervous System 16 | 16,725
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Non-IDG 10 | 12,091
Enzyme 6 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

GO Process

mRNA catabolic process 18 | 18
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein argonaute-4 AGO4 Tbio Non-IDG -1.42077 23.0 121
N6-adenosine-methyltransferase catalytic subunit METTL3 Tbio Enzyme -1.76174 60.5 94
Heat shock 70 kDa protein 1A HSPA1B Tchem Non-IDG -3.10995 0.00000 1174
Heat shock 70 kDa protein 1B HSPA1B Tbio Non-IDG -1.61862 0.00000 60
Zinc fingers and homeoboxes protein 2 ZHX2 Tbio Transcription Factor -1.64146 42.7 460
mRNA decay activator protein ZFP36L2 ZFP36L2 Tbio Non-IDG -1.54477 30.6 140
Protein SLFN14 SLFN14 Tbio Non-IDG -0.61542 3.98 53
N6-adenosine-methyltransferase non-catalytic subunit METTL14 Tbio Enzyme -1.17650 11.6 45
Ribonuclease inhibitor RNH1 Tbio Enzyme -2.84047 653.3 276
Nanos homolog 2 NANOS2 Tbio Non-IDG -1.57901 37.3 196