Development Level

Tbio 52 | 11,445
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 34
decreased fasted circulating g... 1 | 65
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 37 | 11,493
ovarian cancer 36 | 8,520
osteosarcoma 24 | 7,950
lung cancer 22 | 4,740
group 3 medulloblastoma 21 | 4,104
medulloblastoma, large-cell 19 | 6,241
psoriasis 17 | 6,694
glioblastoma 15 | 5,792
Breast cancer 13 | 3,578
ependymoma 13 | 4,679
Multiple myeloma 12 | 1,332
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
malignant mesothelioma 12 | 3,232
acute quadriplegic myopathy 11 | 1,158
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
non-small cell lung cancer 11 | 2,890
Kidney cancer 9 | 2,613
primitive neuroectodermal tumor 9 | 3,035
Waldenstrons macroglobulinemia 8 | 765
atypical teratoid / rhabdoid tumor 8 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
oligodendroglioma 8 | 2,850
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
lung adenocarcinoma 7 | 2,716
tuberculosis and treatment for 6 months 7 | 409
Gaucher disease type 1 6 | 180
Pick disease 6 | 1,894
invasive ductal carcinoma 6 | 2,951
subependymal giant cell astrocytoma 6 | 2,287
dermatomyositis 5 | 966
group 4 medulloblastoma 5 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
progressive supranuclear palsy 5 | 676
HIV Infections 4 | 102
Intellectual disability 4 | 1,016
adult high grade glioma 4 | 3,801
aldosterone-producing adenoma 4 | 665
diabetes mellitus 4 | 1,728
juvenile dermatomyositis 4 | 1,187
nasopharyngeal carcinoma 4 | 1,058
pediatric high grade glioma 4 | 1,064
Autosomal recessive predisposition 3 | 1,442
Cancer 3 | 2,499
Microcephaly 3 | 166
acute myeloid leukemia 3 | 783
adrenocortical carcinoma 3 | 1,428
atypical teratoid/rhabdoid tumor 3 | 357
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
hepatocellular carcinoma 3 | 547
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
posterior fossa group B ependymoma 3 | 416
spina bifida 3 | 1,074
Acquired immunodeficiency syndrome 2 | 197
Acrofacial dysostosis 2 | 8
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Bilateral fifth finger clinodactyly 2 | 110
Bipolar Disorder 2 | 666
Byzanthine arch palate 2 | 194
Cognitive delay 2 | 608
Cryptorchidism 2 | 296
Curvature of little finger 2 | 110
Disease Progression 2 | 136
Global developmental delay 2 | 608
Hematologic cancer 2 | 12
Immune system cancer 2 | 140
Male infertility 2 | 206
Mastocytosis 2 | 27
Mental and motor retardation 2 | 608
Neuronal ceroid lipofuscinosis 1 2 | 15
Polycystic ovary syndrome 2 | 360
Polycythemia vera 2 | 27
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Spinocerebellar ataxia type 31 2 | 8
Stomach Neoplasms 2 | 300
interstitial cystitis 2 | 2,312
non primary Sjogren syndrome sicca 2 | 891
pancreatic carcinoma 2 | 562
primary pancreatic ductal adenocarcinoma 2 | 1,109
relapsing-remitting multiple sclerosis 2 | 18
tuberculosis and treatment for 3 months 2 | 179
Abnormality of the pharynx 1 | 19
Acute Promyelocytic Leukemia 1 | 40
Amebiasis 1 | 21
Aortic Valve Insufficiency 1 | 40
Deglutition Disorders 1 | 132
Dyspepsia 1 | 33
Esotropia 1 | 31
Hypobetalipoproteinemia 1 | 3
Kaposi's sarcoma 1 | 22
Muscle weakness of limb 1 | 21
Myelodysplastic Syndromes 1 | 26
Rectal prolapse 1 | 19
Rift Valley fever 1 | 14
Spinocerebellar ataxia type 1 1 | 16
West Nile encephalitis 1 | 9

Tissue

Blood and immune system 55 | 16,909
Cardiovascular System 55 | 15,192
Digestive Tract 55 | 17,369
Endocrine System 55 | 18,159
Female tissues 55 | 17,400
Liver and Pancreas 55 | 16,750
Male tissues 55 | 17,142
Nervous System 55 | 16,725
Respiratory system 55 | 16,393
Skin and soft tissues 55 | 17,230
Urinary Tract 55 | 16,678

Target Family

Non-IDG 49 | 12,091
Enzyme 6 | 4,145

GO Process

mRNA 3'-end processing 55 | 55
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
THO complex subunit 7 homolog THOC7 Tbio Non-IDG -0.34772 2.04 61
THO complex subunit 5 homolog THOC5 Tbio Non-IDG -1.14189 16.8 116
Cleavage and polyadenylation specificity factor subunit 3 CPSF3 Tbio Non-IDG -1.47182 27.3 190
THO complex subunit 6 homolog THOC6 Tbio Non-IDG -1.77416 57.9 131
Splicing factor U2AF 26 kDa subunit U2AF1L4 Tbio Non-IDG -0.17609 1.86 61
Polyadenylate-binding protein 2 PABPN1 Tbio Non-IDG -2.48757 316.4 120
Cleavage and polyadenylation specificity factor subunit 1 CPSF1 Tbio Non-IDG -1.00806 8.79 51
Pre-mRNA cleavage complex 2 protein Pcf11 PCF11 Tbio Non-IDG -1.38684 23.0 33
Spliceosome RNA helicase DDX39B DDX39B Tbio Enzyme -1.74494 60.6 182