Development Level

Tbio 27 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal behavior 6 | 298
abnormal bone structure 5 | 187
decreased bone mineral density 4 | 126
preweaning lethality, complete... 4 | 979
abnormal bone mineralization 2 | 38
abnormal retina morphology 2 | 71
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal iris morphology 1 | 13
abnormal locomotor activation 1 | 16
abnormal lung morphology 1 | 26
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating lactate ... 1 | 3
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
impaired righting response 1 | 26
increased B cell number 1 | 9
increased blood urea nitrogen ... 1 | 48
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
persistence of hyaloid vascula... 1 | 33
short tibia 1 | 97
stereotypic behavior 1 | 3
trunk curl 1 | 16

Disease

Carcinoma 24 | 11,493
ovarian cancer 19 | 8,520
osteosarcoma 16 | 7,950
glioblastoma 11 | 5,792
medulloblastoma, large-cell 11 | 6,241
Autosomal recessive predisposition 10 | 1,442
Neurodegenerative disease 9 | 414
atypical teratoid / rhabdoid tumor 9 | 5,112
Astrocytoma, Pilocytic 8 | 3,081
group 3 medulloblastoma 8 | 4,104
Schizophrenia 7 | 1,160
adult high grade glioma 7 | 3,801
ependymoma 7 | 4,679
psoriasis 7 | 6,694
subependymal giant cell astrocytoma 7 | 2,287
Kidney cancer 6 | 2,613
Pick disease 6 | 1,894
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
primitive neuroectodermal tumor 6 | 3,035
tuberculosis 6 | 2,010
Alzheimer's disease 5 | 658
Hepatomegaly 5 | 285
Splenomegaly 5 | 190
acute quadriplegic myopathy 5 | 1,158
astrocytic glioma 5 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
non primary Sjogren syndrome sicca 5 | 891
Dull intelligence 4 | 645
Epilepsy 4 | 792
Intellectual disability 4 | 1,016
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
Seizures 4 | 596
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
oligodendroglioma 4 | 2,850
pediatric high grade glioma 4 | 1,064
spina bifida 4 | 1,074
Batten disease 3 | 13
Breast cancer 3 | 3,578
Cardiomegaly 3 | 116
Cerebellar Ataxia 3 | 304
Coarse facial features 3 | 108
Congenital deafness 3 | 185
Crohn's disease 3 | 321
Deafness 3 | 198
Decreased tendon reflex 3 | 122
Dementia 3 | 175
Extinguished electroretinogram 3 | 15
Hearing Loss, Partial 3 | 185
Hermansky-Pudlak syndrome 3 | 42
Macroglossia 3 | 65
Mucopolysaccharidosis 3 | 26
Neuropathy 3 | 261
Prostatic Neoplasms 3 | 495
Thickened facial skin with coarse facial features 3 | 108
dermatomyositis 3 | 966
group 4 medulloblastoma 3 | 1,855
hearing impairment 3 | 199
inclusion-cell disease 3 | 16
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
juvenile dermatomyositis 3 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Amyotrophic lateral sclerosis 2 | 451
Anemia 2 | 365
Big calvaria 2 | 147
Blind Vision 2 | 111
Blindness 2 | 88
Blindness, Legal 2 | 110
Cardiomyopathies 2 | 110
Cerebral atrophy 2 | 178
Degenerative brain disorder 2 | 100
Dysarthria 2 | 192
Fever 2 | 138
Hemoglobin low 2 | 124
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Liver cancer 2 | 604
Low Vision 2 | 174
Melanoma 2 | 711
Multiple Sclerosis 2 | 540
Parkinson Disease 2 | 64
Parkinson's disease 2 | 392
Polycystic ovary syndrome 2 | 360
Recurrent respiratory infections 2 | 141
Reflex, Deep Tendon, Absent 2 | 92
Retinal Degeneration 2 | 106
Supratentorial atrophy 2 | 94
Toxic encephalopathy 2 | 141
Visual Impairment 2 | 174
active ulcerative colitis 2 | 764
medulloblastoma 2 | 720

Tissue

Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Skin and soft tissues 33 | 17,230
Blood and immune system 32 | 16,909
Cardiovascular System 32 | 15,192
Liver and Pancreas 32 | 16,750
Respiratory system 32 | 16,393
Urinary Tract 32 | 16,678

Target Family

Non-IDG 19 | 12,091
Enzyme 9 | 4,145
Transcription Factor 2 | 1,400
Ion Channel 1 | 344
Kinase 1 | 634
Transporter 1 | 473

GO Process

lysosome organization 33 | 33
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysosomal-trafficking regulator LYST Tbio Non-IDG -1.96473 92.5 15
Protein Hook homolog 1 HOOK1 Tbio Non-IDG -1.16190 13.1 187
Zinc finger protein with KRAB and SCAN domains 3 ZKSCAN3 Tbio Transcription Factor -0.90118 10.2 101
Alpha-N-acetylglucosaminidase NAGLU Tbio Enzyme -2.18649 159.9 64
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Transmembrane protein 106B TMEM106B Tbio Non-IDG -1.54017 36.2 87
Lysosomal acid phosphatase ACP2 Tbio Enzyme -2.38317 237.0 83
Arylsulfatase B ARSB Tbio Enzyme -2.51626 314.5 216
Clavesin-1 CLVS1 Tbio Non-IDG -0.31702 2.43 61
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta GNPTAB Tbio Enzyme -2.17166 147.1 57