Development Level

Tbio 15 | 11,445
Tdark 6 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 6 | 979
hemorrhage 4 | 23
abnormal craniofacial morpholo... 2 | 33
abnormal embryo size 2 | 220
abnormal facial morphology 2 | 17
abnormal limb bud morphology 2 | 17
abnormal limb morphology 2 | 13
edema 2 | 59
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal body wall morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal head shape 1 | 10
abnormal optic disc morphology 1 | 10
abnormal outer ear morphology 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal tail morphology 1 | 25
abnormal thoracic cage shape 1 | 3
abnormal vertebrae morphology 1 | 18
anophthalmia 1 | 33
cleft palate 1 | 8
convulsive seizures 1 | 13
cyanosis 1 | 7
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
facial cleft 1 | 3
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
pale liver 1 | 6
polycystic kidney 1 | 15
polydactyly 1 | 7
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 11 | 11,493
ovarian cancer 9 | 8,520
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
glioblastoma 7 | 5,792
atypical teratoid / rhabdoid tumor 6 | 5,112
lung cancer 6 | 4,740
Astrocytoma, Pilocytic 5 | 3,081
Hermansky-Pudlak syndrome 5 | 42
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
primitive neuroectodermal tumor 5 | 3,035
Multiple myeloma 4 | 1,332
oligodendroglioma 4 | 2,850
psoriasis 4 | 6,694
Neurodegenerative disease 3 | 414
Pick disease 3 | 1,894
Platelet storage pool deficiency 3 | 21
Schizophrenia 3 | 1,160
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
group 4 medulloblastoma 3 | 1,855
medulloblastoma 3 | 720
non primary Sjogren syndrome sicca 3 | 891
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
ARC syndrome 2 | 13
Amyotrophic lateral sclerosis 2 | 451
Autosomal recessive predisposition 2 | 1,442
Death in early childhood 2 | 82
Death in infancy 2 | 82
Low set ears 2 | 181
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
primary pancreatic ductal adenocarcinoma 2 | 1,109
Amyotrophic neuralgia 1 | 13
Birthmark 1 | 35
Brain cancer 1 | 30
Brain hemorrhage 1 | 14
Cafe-au-Lait Spots 1 | 37
Cellulitis 1 | 20
Cerebral Hemorrhage 1 | 42
Cervical cancer 1 | 24
Charcot-Marie-Tooth disease 1 | 62
Conjugated hyperbilirubinemia 1 | 14
Cutaneous fibrous histiocytoma 1 | 17
Decreased motor NCV 1 | 22
Dehydration 1 | 40
Elevated heart rate 1 | 25
Elevated urinary norepinephrine 1 | 5
Fibrous histiocytoma 1 | 7
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gait, Drop Foot 1 | 24
Griscelli syndrome 1 | 24
Hemangioma 1 | 69
Hermanski-Pudlak Syndrome 1 | 8
Hyperactive behavior 1 | 91
Hypercalcemia 1 | 59
Hyperkinesis 1 | 32
Hypertension, episodic 1 | 5
Hypertensive Retinopathy 1 | 14
Hypomyelinating leukodystrophy 1 | 9
Hypoplastic feet 1 | 66
Increased calcium level in kidney 1 | 21
Juvenile xanthogranuloma 1 | 7
Kidney damage 1 | 25
Klippel-Trenaunay syndrome 1 | 13
Left ventricular noncompaction 1 | 26
Metabolic acidosis 1 | 90
Mild Mental Retardation 1 | 70
Mood swings 1 | 77
Nonorganic psychosis 1 | 84
Onion bulb formation 1 | 19
Ornithosis 1 | 9
Osteopetrosis 1 | 43
Ovarian Neoplasms 1 | 102
Paraganglioma 1 | 15
Pheochromocytoma 1 | 24
Platyspondyly 1 | 56
Polyneuropathy 1 | 64
Positive regitine blocking test 1 | 5
Pulmonary Fibrosis 1 | 106
Renal Artery Stenosis 1 | 9
Renal tubular acidosis 1 | 24
Rhizomelia 1 | 25
Short hands 1 | 50
Varicose veins 1 | 20
Venous insufficiency 1 | 9
X-linked dominant 1 | 57
ovarian neoplasm 1 | 99

Tissue

Blood and immune system 21 | 16,909
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678

Target Family

Non-IDG 19 | 12,091
Enzyme 2 | 4,145
Epigenetic 1 | 242

GO Process

lysosome localization 22 | 22
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pleckstrin homology domain-containing family M member 1 PLEKHM1 Tbio Non-IDG -1.44998 27.9 116
Transmembrane protein 106B TMEM106B Tbio Non-IDG -1.54017 36.2 87
ADP-ribosylation factor-like protein 8B ARL8B Tbio Enzyme -0.99083 12.0 99
Biogenesis of lysosome-related organelles complex 1 subunit 2 BLOC1S2 Tbio Non-IDG -2.89123 759.6 79
Biogenesis of lysosome-related organelles complex 1 subunit 1 BLOC1S1 Tbio Non-IDG -1.17005 16.2 49
Pleckstrin homology domain-containing family M member 2 PLEKHM2 Tbio Non-IDG -0.32760 3.56 65
Ras-related protein Rab-34 RAB34 Tbio Enzyme -1.77250 102.9 72
Vacuolar protein sorting-associated protein 33A VPS33A Tbio Non-IDG -0.94266 9.42 45
BLOC-1-related complex subunit 5 BORCS5 Tdark Non-IDG 0.46 0.30 95
SNARE-associated protein Snapin SNAPIN Tbio Non-IDG -1.65821 50.9 69