Development Level

Tbio 10 | 11,445
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

increased circulating alkaline... 3 | 122
preweaning lethality, complete... 3 | 979
abnormal bone structure 2 | 187
hypoactivity 2 | 132
abnormal epididymis morphology 1 | 42
abnormal lung morphology 1 | 26
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased total body fat amoun... 1 | 207
enlarged epididymis 1 | 31
enlarged lymph nodes 1 | 37
enlarged urinary bladder 1 | 8
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 10 | 11,493
ovarian cancer 7 | 8,520
osteosarcoma 6 | 7,950
psoriasis 5 | 6,694
glioblastoma 4 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
non primary Sjogren syndrome sicca 4 | 891
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Hypomyelinating leukodystrophy 6 3 | 26
Kidney cancer 3 | 2,613
Neurodegenerative disease 3 | 414
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
tuberculosis 3 | 2,010
Amyotrophic lateral sclerosis 2 | 451
Atherosclerosis 2 | 291
Autosomal dominant Robinow syndrome 2 2 | 22
Cognitive delay 2 | 608
Coronary artery disease 2 | 268
Dementia 2 | 175
Dull intelligence 2 | 645
Epilepsy 2 | 792
Global developmental delay 2 | 608
Hepatomegaly 2 | 285
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Monkeypox 2 | 12
Mucopolysaccharidosis 2 | 26
Multiple myeloma 2 | 1,332
Poor school performance 2 | 645
Seizures 2 | 596
Splenomegaly 2 | 190
active Crohn's disease 2 | 922
lung adenocarcinoma 2 | 2,716
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
Abetalipoproteinemia 1 | 7
Adenocarcinoma 1 | 122
Ataxia 1 | 15
Brucellosis 1 | 24
Cardiomyopathies 1 | 110
Claw hand 1 | 26
Cloudy cornea 1 | 33
Congenital deafness 1 | 185
Corneal stromal opacities 1 | 33
D-2-hydroxyglutaric aciduria 1 | 9
Degenerative brain disorder 1 | 100
Deglutition Disorders 1 | 132
Ebola hemorrhagic fever 1 | 13
Flared iliac wings 1 | 13
Gangliosidosis 1 | 20
Gastrointestinal Stromal Tumors 1 | 48
Gaucher disease type 1 1 | 180
Heart valve disease 1 | 39
Hemolytic-Uremic Syndrome 1 | 30
Hirsutism 1 | 47
Hodgkin's lymphoma 1 | 15
Hypomyelinating leukodystrophy 1 | 9
Iron metabolism disease 1 | 20
Irritation - emotion 1 | 68
Joint stiffness 1 | 84
Keloid 1 | 37
Kluver-Bucy syndrome 1 | 6
Knee joint valgus deformity 1 | 56
Leukodystrophy 1 | 55
Liddle syndrome 1 | 14
Loss of speech 1 | 16
Macular holes 1 | 11
Metachromatic leukodystrophy 1 | 14
Metaphyseal irregularity 1 | 23
Mucopolysaccharidosis III 1 | 7
Mucopolysaccharidosis VI 1 | 6
Mucosulfatidosis 1 | 5
Nasopharyngitis 1 | 11
Nephroblastoma 1 | 51
Nerve Degeneration 1 | 121
Neurofibrillary degeneration (morphologic abnormality) 1 | 9
Niemann-Pick disease, type C 1 | 5
ODONTOID HYPOPLASIA 1 | 16
Pfaundler-Hurler Syndrome 1 | 12
Progressive microcephaly 1 | 32
Pseudohypoaldosteronism 1 | 23
Recurrent upper respiratory tract infection 1 | 21
Retinitis pigmentosa 28 1 | 19
Short-trunked dwarfism 1 | 13
Skin disease 1 | 66
Spastic Quadriplegia 1 | 42
Stevens-Johnson syndrome 1 | 92
Supratentorial atrophy 1 | 94
hearing impairment 1 | 199
inflammatory breast cancer 1 | 286

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Cardiovascular System 11 | 15,192

Target Family

Non-IDG 8 | 12,091
Enzyme 4 | 4,145

GO Process

lysosomal transport 12 | 12
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 106B TMEM106B Tbio Non-IDG -1.54017 36.2 87
Niemann-Pick C1 protein NPC1 Tbio Non-IDG -2.71962 551.3 284
Arylsulfatase B ARSB Tbio Enzyme -2.51626 314.5 216
Vacuolar protein sorting-associated protein 54 VPS54 Tbio Non-IDG -1.18501 15.3 95
E3 ubiquitin-protein ligase NEDD4 NEDD4 Tchem Enzyme -2.44046 259.8 167
Heparan-alpha-glucosaminide N-acetyltransferase HGSNAT Tbio Enzyme -1.43006 29.3 31
Vacuolar protein sorting-associated protein 53 homolog VPS53 Tbio Non-IDG -0.81954 6.51 106
Vacuolar protein sorting-associated protein 51 homolog VPS51 Tbio Non-IDG -2.64126 419.3 58
Vesicle transport protein USE1 USE1 Tbio Non-IDG -2.63368 401.2 166
Proprotein convertase subtilisin/kexin type 9 PCSK9 Tclin Enzyme -3.23656 1735.1 468