Development Level

Tbio 2 | 11,651

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

Carcinoma 2 | 11,493
lung cancer 2 | 4,740
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
Andersen-Tawil syndrome 1 | 8
Anemia 1 | 365
Astrocytoma, Pilocytic 1 | 3,081
Autosomal recessive predisposition 1 | 1,442
Breast cancer 1 | 3,578
Cardiovascular system disease 1 | 246
Carpenter syndrome 1 | 10
Citrullinemia 1 | 14
Craniopharyngioma 1 | 16
Cystinuria 1 | 18
Delayed speech and language development 1 | 112
Disorder of the genitourinary system 1 | 6
Dull intelligence 1 | 645
Ectopia Lentis 1 | 17
Electroencephalogram abnormal 1 | 101
Epilepsy 1 | 792
Genitourinary dysplasia 1 | 6
Hemoglobin low 1 | 124
Highly variable clinical phenotype 1 | 150
Highly variable phenotype and severity 1 | 150
Highly variable phenotype, even within families 1 | 150
Histidinuria renal tubular defect 1 | 1
Hyperactive behavior 1 | 91
Hyperlysinemia 1 | 6
Hyperlysinemias 1 | 1
Hyperlysinuria 1 | 3
Impaired cognition 1 | 96
Infantile onset 1 | 238
Intellectual disability 1 | 1,016
Kidney cancer 1 | 2,613
Language Delay 1 | 112
Little's Disease 1 | 14
Low intelligence 1 | 645
Lysine Alpha-Ketoglutarate Reductase Deficiency Disease 1 | 1
Maxillary sinusitis 1 | 2
Mental Retardation 1 | 645
Mental deficiency 1 | 645
Mental impairment 1 | 95
Mild Mental Retardation 1 | 70
Multiple myeloma 1 | 1,332
Muscle hypotonia 1 | 571
Ornithine translocase deficiency 1 | 7
Orotic aciduria 1 | 18
Parkinson's disease 1 | 392
Phenotypic variability 1 | 150
Poor school performance 1 | 645
Reduced concentration span 1 | 9
Retinitis pigmentosa 24 1 | 15
Saccharopine dehydrogenase deficiency 1 | 1
Saccharopinuria 1 | 1
Seizures 1 | 596
Short stature 1 | 531
Speech Delay 1 | 112
Speech impairment 1 | 112
Urogenital Abnormalities 1 | 9
Waldenstrons macroglobulinemia 1 | 765
acute myeloid leukemia 1 | 783
astrocytic glioma 1 | 2,597
ductal carcinoma in situ 1 | 1,745
ependymoma 1 | 4,679
glioblastoma 1 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
invasive ductal carcinoma 1 | 2,951
malignant mesothelioma 1 | 3,232
oligodendroglioma 1 | 2,850
osteosarcoma 1 | 7,950
pituitary cancer 1 | 1,972
primitive neuroectodermal tumor 1 | 3,035
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Enzyme 2 | 4,145

GO Process

lysine biosynthetic process vi... 2 | 2
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..