Development Level

Tbio 46 | 10,625
Tchem 23 | 1,890
Tclin 4 | 602
Tdark 1 | 7,003

IMPC Phenotype

preweaning lethality, complete... 7 | 633
preweaning lethality, incomple... 4 | 260
abnormal embryo size 2 | 112
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased lean body mass 2 | 195
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
impaired glucose tolerance 2 | 52
prenatal lethality prior to he... 2 | 64
abnormal behavior 1 | 226
abnormal coat-hair pigmentatio... 1 | 54
abnormal eye morphology 1 | 38
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 2
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retinal pigmentation 1 | 61
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
absent heartbeat 1 | 6
absent vibrissae 1 | 14
cataract 1 | 26
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating chloride... 1 | 32
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 19
improved glucose tolerance 1 | 56
increased circulating creatini... 1 | 29
increased circulating free fat... 1 | 17
increased circulating glycerol... 1 | 11
increased startle reflex 1 | 38
limb grasping 1 | 35
pale yolk sac 1 | 12

Disease

osteosarcoma 40 | 7,933
ovarian cancer 40 | 8,491
Cancer 37 | 2,346
psoriasis 35 | 6,685
glioblastoma 33 | 5,572
medulloblastoma, large-cell 30 | 6,234
atypical teratoid / rhabdoid tumor 28 | 4,369
lung cancer 28 | 4,473
malignant mesothelioma 28 | 3,163
lung adenocarcinoma 25 | 2,714
lung carcinoma 24 | 2,844
primitive neuroectodermal tumor 24 | 3,031
pediatric high grade glioma 23 | 2,712
interstitial cystitis 21 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
non-small cell lung cancer 20 | 2,798
pilocytic astrocytoma 20 | 3,086
Breast cancer 19 | 3,098
pituitary cancer 18 | 1,972
Carcinoma 17 | 2,147
breast carcinoma 17 | 1,614
invasive ductal carcinoma 17 | 2,950
ductal carcinoma in situ 16 | 1,745
ependymoma 16 | 2,514
group 3 medulloblastoma 16 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
cystic fibrosis 15 | 1,670
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
pancreatic cancer 15 | 2,300
ulcerative colitis 15 | 2,087
Atopic dermatitis 14 | 944
adrenocortical carcinoma 14 | 1,427
oligodendroglioma 14 | 2,849
sonic hedgehog group medulloblastoma 14 | 1,482
subependymal giant cell astrocytoma 13 | 2,287
primary pancreatic ductal adenocarcinoma 12 | 1,271
Obesity 11 | 616
adult high grade glioma 11 | 2,148
posterior fossa group A ependymoma 11 | 1,511
acute quadriplegic myopathy 10 | 1,157
colon cancer 10 | 1,475
astrocytic glioma 9 | 2,241
astrocytoma 9 | 1,493
gastric carcinoma 9 | 832
group 4 medulloblastoma 9 | 1,875
Craniofacial Abnormalities 8 | 147
Heart disease 8 | 279
Hypertension 8 | 293
Pick disease 8 | 1,893
atypical teratoid/rhabdoid tumor 8 | 1,095
diabetes mellitus 8 | 1,663
juvenile dermatomyositis 8 | 1,189
nasopharyngeal carcinoma 8 | 1,056
non primary Sjogren syndrome sicca 8 | 840
non-small cell lung carcinoma 8 | 413
Atherosclerosis 7 | 275
Liver Cirrhosis 7 | 101
Mammary Neoplasms 7 | 410
Polycystic Ovary Syndrome 7 | 334
Rheumatoid Arthritis 7 | 1,170
aldosterone-producing adenoma 7 | 664
cutaneous lupus erythematosus 7 | 1,056
medulloblastoma 7 | 1,524
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
posterior fossa group B ependymoma 7 | 1,530
tuberculosis 7 | 1,563
Adenoma 6 | 165
Cleft palate 6 | 125
Congenital diaphragmatic hernia 6 | 44
Down syndrome 6 | 548
Holoprosencephaly 6 | 52
Liver disease 6 | 219
Lung Neoplasms 6 | 171
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 499
fibroadenoma 6 | 557
spina bifida 6 | 1,064
Alzheimer's disease 5 | 644
Arthritis 5 | 248
Cerebrovascular disease 5 | 231
Cleft Lip 5 | 91
Colonic Neoplasms 5 | 126
Diabetes Mellitus, Non-Insulin-Dependent 5 | 161
Duchenne muscular dystrophy 5 | 602
Intellectual disability 5 | 573
Kidney cancer 5 | 121
Kidney disease 5 | 397
Liver Cirrhosis, Experimental 5 | 108
Lung disease 5 | 136
Lung diseases 5 | 48
Multiple myeloma 5 | 1,327
Polydactyly 5 | 93
Situs Inversus 5 | 52
Stomach Neoplasms 5 | 282
Uterine Cervical Neoplasm 5 | 21
Waldenstrons macroglobulinemia 5 | 764
active Crohn's disease 5 | 918
active ulcerative colitis 5 | 477
chronic rhinosinusitis 5 | 512
inflammatory breast cancer 5 | 404
mucosa-associated lymphoid tissue lymphoma 5 | 480

Tissue

Cardiovascular System 74 | 17,957
Digestive Tract 74 | 18,472
Endocrine System 74 | 18,511
Female tissues 74 | 18,646
Male tissues 74 | 17,968
Nervous System 74 | 18,560
Skin and soft tissues 74 | 18,114
Liver and Pancreas 73 | 18,135
Respiratory system 73 | 17,483
Urinary Tract 73 | 18,443
Blood and immune system 72 | 17,994

Target Family

Non-IDG 35 | 11,969
Transcription Factor 18 | 1,400
Enzyme 14 | 4,146
Kinase 5 | 634
Epigenetic 1 | 242
Transporter 1 | 473

GO Process

lung development 74 | 74
transcription, DNA-templated 1,779 | 1,779
regulation of transcription, D... 1,170 | 1,170
signal transduction 969 | 969
positive regulation of transcr... 845 | 845
G-protein coupled receptor sig... 666 | 666
negative regulation of transcr... 620 | 620
apoptotic process 506 | 506
positive regulation of transcr... 504 | 504
negative regulation of transcr... 483 | 483
multicellular organism develop... 456 | 456
positive regulation of cell pr... 451 | 451
cell differentiation 442 | 442
negative regulation of apoptot... 440 | 440
innate immune response 410 | 410
cell adhesion 409 | 409
immune response 398 | 398
negative regulation of cell pr... 379 | 379
inflammatory response 371 | 371
viral process 367 | 367
spermatogenesis 365 | 365
cell proliferation 358 | 358
protein transport 356 | 356
intracellular signal transduct... 355 | 355
cell division 330 | 330
regulation of transcription fr... 324 | 324
protein phosphorylation 320 | 320
response to drug 297 | 297
positive regulation of apoptot... 292 | 292
nervous system development 275 | 275
transcription from RNA polymer... 272 | 272
cell surface receptor signalin... 267 | 267
protein ubiquitination 260 | 260
transport 257 | 257
cell-cell signaling 249 | 249
regulation of immune response 247 | 247
positive regulation of gene ex... 242 | 242
mitotic nuclear division 241 | 241
chemical synaptic transmission 238 | 238
MAPK cascade 237 | 237
mRNA splicing, via spliceosome 219 | 219
angiogenesis 218 | 218
small GTPase mediated signal t... 215 | 215
translation 215 | 215
rRNA processing 209 | 209
intracellular protein transpor... 205 | 205
cellular response to DNA damag... 201 | 201
cell cycle 200 | 200
proteasome-mediated ubiquitin-... 199 | 199
proteolysis 199 | 199
visual perception 198 | 198
DNA repair 196 | 196
extracellular matrix organizat... 193 | 193
regulation of apoptotic proces... 190 | 190
brain development 183 | 183
positive regulation of cell mi... 181 | 181
protein polyubiquitination 180 | 180
in utero embryonic development 178 | 178
Fc-epsilon receptor signaling ... 175 | 175
Wnt signaling pathway 175 | 175
ion transmembrane transport 174 | 174
protein homooligomerization 173 | 173
heart development 170 | 170
positive regulation of ERK1 an... 170 | 170
blood coagulation 169 | 169
cell migration 168 | 168
regulation of cell proliferati... 167 | 167
protein autophosphorylation 166 | 166
response to hypoxia 164 | 164
mRNA processing 162 | 162
protein folding 162 | 162
negative regulation of canonic... 161 | 161
response to lipopolysaccharide 161 | 161
T cell receptor signaling path... 160 | 160
defense response to virus 160 | 160
RNA splicing 158 | 158
aging 158 | 158
positive regulation of I-kappa... 158 | 158
axon guidance 157 | 157
homophilic cell adhesion via p... 155 | 155
sensory perception of smell 155 | 155
ER to Golgi vesicle-mediated t... 151 | 151
interferon-gamma-mediated sign... 150 | 150
protein ubiquitination involve... 150 | 150
transcription initiation from ... 150 | 150
ubiquitin-dependent protein ca... 149 | 149
DNA replication 144 | 144
adaptive immune response 139 | 139
cell cycle arrest 139 | 139
receptor-mediated endocytosis 139 | 139
skeletal system development 136 | 136
regulation of cell shape 135 | 135
regulation of small GTPase med... 134 | 134
G2-M transition of mitotic cel... 133 | 133
oxidation-reduction process 133 | 133
positive regulation of cytosol... 133 | 133
protein stabilization 133 | 133
sensory perception of sound 132 | 132
positive regulation of NF-kapp... 131 | 131
type I interferon signaling pa... 130 | 130
endocytosis 129 | 129

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Intraflagellar transport protein 25 homolog HSPB11 Tbio Non-IDG -1.36468 21.9 56
Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 Tclin Enzyme -2.88110 850.3 270
Protein timeless homolog TIMELESS Tbio Non-IDG -2.74942 550.7 135
Podoplanin PDPN Tbio Non-IDG -3.30677 1987.7 771
Stimulated by retinoic acid gene 6 protein homolog STRA6 Tbio Non-IDG -1.73885 61.1 134
Transcription factor Sp3 SP3 Tbio Transcription Factor -2.48548 281.9 319
Mothers against decapentaplegic homolog 2 SMAD2 Tbio Transcription Factor -3.22108 1085.0 1249
Cytochrome P450 1A2 CYP1A2 Tchem Non-IDG -3.31421 2022.5 420
Collagen and calcium-binding EGF domain-containing protein 1 CCBE1 Tbio Non-IDG -1.21092 17.1 137
Connective tissue growth factor CTGF Tchem Non-IDG -3.25038 1870.5 497