Development Level

Tbio 20 | 11,445
Tchem 4 | 1,598
Tclin 4 | 613
Tdark 3 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal testis morphology 1 | 43
absent vibrissae 1 | 12
decreased eosinophil cell numb... 1 | 24
edema 1 | 59
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
increased circulating calcium ... 1 | 34
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

Carcinoma 22 | 11,493
ovarian cancer 20 | 8,520
medulloblastoma, large-cell 15 | 6,241
atypical teratoid / rhabdoid tumor 14 | 5,112
glioblastoma 14 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
osteosarcoma 13 | 7,950
Breast cancer 12 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
lung cancer 12 | 4,740
malignant mesothelioma 12 | 3,232
Cancer 11 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
psoriasis 11 | 6,694
cystic fibrosis 10 | 1,696
lung adenocarcinoma 10 | 2,716
non-small cell lung cancer 10 | 2,890
pancreatic cancer 10 | 2,398
ulcerative colitis 10 | 1,819
adult high grade glioma 9 | 3,801
invasive ductal carcinoma 9 | 2,951
lung carcinoma 9 | 2,843
group 3 medulloblastoma 8 | 4,104
interstitial cystitis 8 | 2,312
Astrocytoma, Pilocytic 7 | 3,081
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
primary pancreatic ductal adenocarcinoma 7 | 1,109
Breast Neoplasms 6 | 445
Kidney cancer 6 | 2,613
Mammary Neoplasms 6 | 425
acute quadriplegic myopathy 6 | 1,158
cutaneous lupus erythematosus 6 | 1,057
ependymoma 6 | 4,679
oligodendroglioma 6 | 2,850
subependymal giant cell astrocytoma 6 | 2,287
Autosomal recessive predisposition 5 | 1,442
adrenocortical carcinoma 5 | 1,428
interstitial lung disease 5 | 298
juvenile dermatomyositis 5 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
Exophthalmos 4 | 112
Hypertensive disease 4 | 292
Increase in blood pressure 4 | 119
Osteoporosis 4 | 363
Pick disease 4 | 1,894
Prominent eyes 4 | 96
Prominent globes 4 | 96
Protruding eyes 4 | 96
Short stature 4 | 531
colon cancer 4 | 1,478
gastric carcinoma 4 | 807
group 4 medulloblastoma 4 | 1,855
primitive neuroectodermal tumor 4 | 3,035
tuberculosis 4 | 2,010
Amyotrophic lateral sclerosis 3 | 451
Asthma 3 | 385
Atopic dermatitis 3 | 952
Brachycephaly 3 | 88
Broad cranium shape 3 | 88
Byzanthine arch palate 3 | 194
Cardiomegaly 3 | 116
Cleft Lip 3 | 141
Cleft Palate 3 | 271
Cleft uvula 3 | 27
Craniofacial Abnormalities 3 | 151
Cryptorchidism 3 | 296
Depressive disorder 3 | 409
Diaphragmatic Hernia 3 | 40
Down syndrome 3 | 499
Dry skin 3 | 75
Endometrial cancer 3 | 311
Endometriosis 3 | 540
Hernia, Diaphragmatic 3 | 40
High forehead 3 | 102
Hydronephrosis 3 | 89
Hypertension 3 | 396
Hypoplastic mandible condyle 3 | 275
Intellectual disability 3 | 1,016
Liver Cirrhosis, Experimental 3 | 769
Lung Neoplasms 3 | 232
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Orbital separation excessive 3 | 244
Polycystic ovary syndrome 3 | 360
Pulmonary hypertension 3 | 85
Rheumatoid arthritis 3 | 1,191
Tall forehead 3 | 102
Wide skull shape 3 | 88
Xerosis 3 | 75
aldosterone-producing adenoma 3 | 665
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
chronic rhinosinusitis 3 | 512
dermatomyositis 3 | 966
fibroadenoma 3 | 559
inflammatory breast cancer 3 | 286
Thin, sparse hair 2 | 59

Tissue

Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Male tissues 31 | 17,142
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678
Liver and Pancreas 30 | 16,750
Respiratory system 30 | 16,393
Cardiovascular System 29 | 15,192
Nervous System 29 | 16,725

Target Family

Non-IDG 14 | 12,091
Enzyme 5 | 4,145
Kinase 5 | 634
Transcription Factor 4 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transporter 1 | 473

GO Process

lung alveolus development 31 | 31
transcription, DNA-templated 1,742 | 1,742
regulation of transcription, D... 1,135 | 1,135
G-protein coupled receptor sig... 1,053 | 1,053
signal transduction 1,005 | 1,005
positive regulation of transcr... 932 | 932
negative regulation of transcr... 683 | 683
positive regulation of transcr... 529 | 529
apoptotic process 511 | 511
cell differentiation 511 | 511
negative regulation of transcr... 492 | 492
neutrophil degranulation 484 | 484
negative regulation of apoptot... 479 | 479
positive regulation of cell pr... 470 | 470
innate immune response 469 | 469
multicellular organism develop... 460 | 460
cell adhesion 458 | 458
immune response 426 | 426
viral process 405 | 405
negative regulation of cell pr... 398 | 398
spermatogenesis 389 | 389
intracellular signal transduct... 376 | 376
inflammatory response 373 | 373
cell proliferation 366 | 366
post-translational protein mod... 356 | 356
protein transport 348 | 348
protein ubiquitination 347 | 347
cell division 345 | 345
regulation of transcription fr... 345 | 345
protein phosphorylation 334 | 334
nervous system development 321 | 321
positive regulation of apoptot... 320 | 320
response to drug 303 | 303
cell-cell signaling 300 | 300
positive regulation of gene ex... 297 | 297
transcription from RNA polymer... 286 | 286
protein deubiquitination 271 | 271
cell cycle 268 | 268
regulation of immune response 259 | 259
transport 255 | 255
regulation of apoptotic proces... 250 | 250
MAPK cascade 242 | 242
cell surface receptor signalin... 239 | 239
mRNA splicing, via spliceosome 236 | 236
protein polyubiquitination 222 | 222
angiogenesis 220 | 220
chemical synaptic transmission 219 | 219
cellular response to DNA damag... 217 | 217
proteolysis 217 | 217
proteasome-mediated ubiquitin-... 210 | 210
adaptive immune response 209 | 209
intracellular protein transpor... 209 | 209
DNA repair 206 | 206
leukocyte migration 206 | 206
protein homooligomerization 206 | 206
rRNA processing 204 | 204
extracellular matrix organizat... 198 | 198
visual perception 198 | 198
positive regulation of ERK1 an... 194 | 194
cellular protein metabolic pro... 192 | 192
brain development 188 | 188
axon guidance 186 | 186
Fc-epsilon receptor signaling ... 182 | 182
keratinization 182 | 182
cell migration 181 | 181
defense response to virus 181 | 181
positive regulation of cell mi... 179 | 179
regulation of cell proliferati... 177 | 177
in utero embryonic development 176 | 176
Wnt signaling pathway 175 | 175
cilium assembly 175 | 175
blood coagulation 170 | 170
RNA splicing 169 | 169
translation 169 | 169
mRNA processing 168 | 168
protein autophosphorylation 168 | 168
aging 167 | 167
response to hypoxia 166 | 166
T cell receptor signaling path... 164 | 164
heart development 164 | 164
negative regulation of canonic... 164 | 164
positive regulation of I-kappa... 164 | 164
ubiquitin-dependent protein ca... 164 | 164
ER to Golgi vesicle-mediated t... 162 | 162
protein stabilization 160 | 160
response to lipopolysaccharide 160 | 160
transcription initiation from ... 160 | 160
defense response to bacterium 159 | 159
protein folding 159 | 159
sensory perception of smell 157 | 157
homophilic cell adhesion via p... 156 | 156
transmembrane transport 154 | 154
negative regulation of gene ex... 151 | 151
interferon-gamma-mediated sign... 150 | 150
receptor-mediated endocytosis 150 | 150
ion transmembrane transport 148 | 148
peptidyl-serine phosphorylatio... 148 | 148
positive regulation of protein... 148 | 148
antigen processing and present... 143 | 143
DNA replication 142 | 142
cell cycle arrest 142 | 142

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 12 ABCA12 Tbio Transporter -2.05873 115.5 66
Bone morphogenetic protein receptor type-2 BMPR2 Tchem Kinase -2.66587 458.1 390
Receptor for retinol uptake STRA6 STRA6 Tbio Non-IDG -1.78205 67.9 157
Extracellular tyrosine-protein kinase PKDCC PKDCC Tbio Kinase -1.15951 16.2 51
ERBB receptor feedback inhibitor 1 ERRFI1 Tbio Non-IDG -1.86682 77.3 148
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
Myocardin MYOCD Tbio Non-IDG -2.37801 242.7 84
Insulin-like growth factor-binding protein 5 IGFBP5 Tchem Non-IDG -2.52721 351.8 278
Pulmonary surfactant-associated protein D SFTPD Tbio Non-IDG -2.81488 698.4 291
Forkhead box protein F1 FOXF1 Tbio Transcription Factor -1.96274 100.2 201